Clinical trials: Remifentanil
Endotracheal Intubation
Remifentanil and Atropine for Intubation in Neonates
The investigators hypothesize that the use of a combination of Atropine and Remifentanil will safely facilitate non emergent intubation procedure as effectively as the protocol of Atropine, Fentanyl, and Succinylcholine.
- Trial name
- RAIN (NCT00815048)
- Testing
- Atropine/Remifentanil, Fentanyl/Atropine/Succinylcholine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- King Saud University
Traumatic Brain Injury
Remifentanil for Sedation of Patients With Traumatic Brain Injury (TBI)
This is a descriptive retrospective study designed to measure the efficacy of remifentanil sedation and the ability to perform frequent neurological examinations of patients with traumatic brain injuries.
- Trial name
- NCT02049320
- Testing
- Remifentanil
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Joseph D. Tobias
Anesthesia, Neurotoxicity
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
There is considerable evidence that most general anaesthetics modulate brain development in animal studies. The impact is greater with longer durations of exposure and in younger animals.
- Conditions
- Anesthesia, Neurotoxicity, Child Development
- Trial name
- TREX (NCT03089905)
- Testing
- Sevoflurane, Remifentanil, Dexmedetomidine
- Where
- 21 sites in United States, Australia and 2 more
- Volunteers
- 450 people
- Sponsor
- Murdoch Childrens Research Institute
Pediatric Rigid Bronchoscopy
Remifentanil Use in Pediatric Rigid Bronchoscopy
Purpose: In this study we wanted to compare bolus propofol and ketamine as an adjuvant to remifentanil-based total intravenous anesthesia for pediatric rigid bronchoscopy.
- Trial name
- NCT01947114
- Testing
- Propofol, Ketamine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
General Anesthesia, Children
Comparison of Two Regimens of Anesthesia for Children Undergoing Magnetic Resonance Imaging (MRI) in General Anesthesia
Comparison of two regimens (Sevorane/LMA ctr. Propofol/Remifentanil) for children undergoing MRI in general anesthesia.
- Conditions
- General Anesthesia, Children, MRI, Sevoflurane
- Trial name
- NCT00949507
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Niels Anker Pedersen
Respiratory Complication
the Effective Bolus Dose of Remifentanil for Laryngeal Mask Airway (LMA) Insertion in Children
This research attempts to find the optimum dose of remifentanil that can prevent the unnecessary responses such as coughing, gagging, and movement when LMA is inserted during sevoflurane induction in pediatric patients.
- Trial name
- NCT01919203
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Sangjin Park
Anesthesia, General
Use of Bispectral Index (BIS) for Monitoring of Total Intravenous Anaesthesia in Pediatric Patients
The objective of the study is to determine wether the use of the Bispectral Index Monitor (BIS) as a method to guide anaesthesia for children in different groups of age, undergoing ear nose and throat surgery anaesthetized with…
- Trial name
- NCT01043952
- Testing
- Propofol, Remifentanil, Bispectral Index Monitor
- Where
- Denmark
- Volunteers
- 157 people
- Sponsor
- Aalborg University Hospital
Critical Illness, Pain
Population Pharmacokinetics of Remifentanil in Low-Weight Critically Ill Patients
The goal of this prospective clinical study is to learn about the population pharmacokinetics (PopPK), safety, and efficacy of remifentanil in low-body-weight patients in the Intensive Care Unit (ICU) who require mechanical…
- Trial name
- NCT07301970
- Testing
- Remifentanil
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Fudan University
Scoliosis
Effect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis Surgery
The purpose of this study is to examine if morphine administered by bolus before initiating Remifentanil by infusion decreases the incidence of acute post-operative opioid tolerance as demonstrated by decreased post - operative…
- Trial name
- NCT00737997
- Testing
- Morphine, Saline
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Intubating Condition
Remifentanil Requirement for Acceptable Intubating Condition
Ketamine and opioid are known to improve the intubating condition, respectively. Combination of ketamine and opioid potentiate analgesic effect and give hemodynamic stability in complementary manner.
- Trial name
- NCT02655380
- Testing
- Ketamine 1, Ketamine 2, Remifentanil
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Ajou University School of Medicine
Children, Heart Diseases
Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia
What is the optimal maintenance dose of remifentanil to ensure apnoea, during breath hold episodes in children having cardiac MR imaging with general anaesthesia?
- Conditions
- Children, Heart Diseases, Anaesthesia, Magnetic Resonance Imaging
- Trial name
- NCT02481791
- Testing
- Remifentanil and/or propofol, propofol
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Endotracheal Intubation
Optimum Dose of Remifentanil for Intubation in Small Children
The routine medications to relax the muscles of the throat are an anesthetic drug, propofol, in combination with an ultra short acting pain medicine, remifentanil.
- Trial name
- NCT00474071
- Testing
- Remifentanil
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Spinal Puncture
Co-administration of Propofol and Remifentanil for Lumbar Puncture in Children
The objective of this study is to compare intraoperative and recovery parameters in patients who receive two different dose combinations of propofol and remifentanil in patients undergoing a lumbar puncture.
- Trial name
- NCT00405522
- Testing
- Propofol 2.0 mg/kg + Remifentanil 1.5 ug/kg, Propofol 4.0 mg/kg + Remifentanil 0.5 ug/kg
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- The Hospital for Sick Children
Acute Kidney Injury, Crush Injury
The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in Rats
The goal of this interventional preclinical study is to evaluate the potential protective effects of two intravenous anesthetic agents-dexmedetomidine and remifentanil-on kidney function in the context of muscle crush injury…
- Conditions
- Acute Kidney Injury, Crush Injury, Rhabdomyolysis
- Trial name
- NCT07094165
- Testing
- Dexmedetomidine, Remifentanil, Laparotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara City Hospital Bilkent
Emergence Agitation
Emergence Agitation in Pediatric Strabismus Surgery
This study was performed to assess the effects of continuous remifentanil infusion and single bolus administration of fentanyl on the incidence of emergence agitation in pediatrics undergoing strabismus surgery.
- Trial name
- NCT03807011
- Testing
- fentanyl group, remifentanil group
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Child, Only, Pain
Remifentanil Tapering and Post-adenotonsillectomy Pain in Children
Tonsillectomy is the commonest operation of childhood and results in considerable pain. Remifentanil is a potent, ultra short acting opioid with a long- established safety record in paediatric anaesthesia that is used to provide…
- Conditions
- Child, Only, Pain, Tonsillectomy, Remifentanil
- Trial name
- NCT03994146
- Testing
- Remifentanil, Sodium Chloride 9mg/mL
- Where
- 2 sites in Norway
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Pain Relief in Labour
A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour
Childbirth can be an extremely painful and the provision of pain relief during labour is a vital component of a positive maternal experience.
- Trial name
- RESPITE (NCT02179294)
- Testing
- Pethidine, Remifentanil
- Where
- United Kingdom
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Respiratory Distress Syndrome
Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome
In this randomised controlled study we intended to compared intubation conditions and the continuous infusion of remifentanil (n=10) and morphine (n=10) in mechanically ventilated premature neonates (28-34wk) regarding the time…
- Trial name
- NCT00391105
- Testing
- Remifentanil
- Sponsor
- Federal University of Minas Gerais
Respiratory Distress Syndrome
Propofol Versus Midazolam as Premedication for Preterm Neonates With Respiratory Distress Syndrome (RDS)
The aim of the study is to compare the intubation conditions among propofol and remifentanil versus midazolam and remifentanil in premature neonates with respiratory distress syndrome.
- Trial name
- NCT00797160
- Testing
- propofol
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Minas Gerais
Analgesia
ULTIVA Post Marketing Surveillance
This study is a post-marketing surveillance to monitor safety and efficacy of remifentanil during various surgeries and identify SAEs, adverse drug reactions, and unexpected AEs not described as precautions or warnings and to…
- Trial name
- NCT01299584
- Testing
- Remifentanil
- Volunteers
- 775 people
- Sponsor
- GlaxoSmithKline