Clinical trials: Remifentanil
Shoulder Dislocation
Comparison of Sedation/Analgesia: Midazolam/Morphine Vs Propofol/Remifentanil
For reduction of dislocated shoulder, sedation with propofol and remifentanil should give satisfactory operating conditions and pain relief, and significantly reduce the time to full recovery, compared with morphine and midazolam
- Trial name
- NCT00326352
- Testing
- Sedation with propofol and remifentanil
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Pain
Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus
A standardized tetanic stimulation is applied to patients under propofol-remifentanil TCI, in a cross-over fashion, at two different levels of anesthesia monitored by the BIS: BIS 25 and BIS 55.
- Trial name
- NCT02595476
- Testing
- Remifentanil, propofol, TCI
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hôpital Armand Trousseau
Neurosurgical Patients
COMparative Performance of General Purpose Models
To compare the performance of the Eleveld models for propofol and remifentanil on neurosurgery patients admitted to intensive care with their intraoperative performance.
- Trial name
- NCT06584097
- Where
- 2 sites in Italy
- Volunteers
- 42 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Obstructive Sleep Apnea
Remifentanil in Children With Obstructive Sleep Apnea
This investigation tested the hypothesis that children with obstructive sleep apnea have an increased pharmacodynamic sensitivity to the miotic and respiratory depressant effects of the prototypic μ-opioid agonist remifentanil.
- Trial name
- ROSA (NCT03958396)
- Testing
- Remifentanil Infusion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Emergence Agitation
Emergence Agitation in Pediatric Strabismus Surgery
This study was performed to assess the effects of continuous remifentanil infusion and single bolus administration of fentanyl on the incidence of emergence agitation in pediatrics undergoing strabismus surgery.
- Trial name
- NCT03807011
- Testing
- fentanyl group, remifentanil group
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Patients Requiring Ambulatory Surgery Under General Anesthesia
Propofol for Supreme LMA Insertion With and Without Remifentanil
The aims of this study were to determine the clinically required concentration of propofol for LMA Supreme insertion, and to examine to what extent remifentanil reduces the dose of propofol and improves conditions for it's…
- Trial name
- SC50 (NCT01974648)
- Testing
- propofol, propofol and remifentanil
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Endotracheal Intubation
Remifentanil and Atropine for Intubation in Neonates
The investigators hypothesize that the use of a combination of Atropine and Remifentanil will safely facilitate non emergent intubation procedure as effectively as the protocol of Atropine, Fentanyl, and Succinylcholine.
- Trial name
- RAIN (NCT00815048)
- Testing
- Atropine/Remifentanil, Fentanyl/Atropine/Succinylcholine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- King Saud University
Anesthesia, Pain
Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia
The aim of this prospective randomized study is to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in pediatric anesthesia.
- Conditions
- Anesthesia, Pain, Child
- Trial name
- NCT02683837
- Testing
- Remifentanil, Pupillometry, Sevoflurane
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Urological Surgery
Echocardiographic Study of the Haemodynamic Effects of Remifentanil With and Without Glycopyrrolate in Healthy Children
Study to investigate the influence of remifentanil and glycopyrrolate on cardiac index and blood pressure in children.To differentiate between contractility and the effect of the circulating volume, some of the subjects will…
- Trial name
- NCT00315536
- Testing
- Administration of remifentanil and glycopyrrolate
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Anesthesia
A Study to Evaluate the Safety and Efficacy of Ultiva (Remifentanil Hydrochloride) in Pediatric Participants General Anesthetised
The purpose of this study is to evaluate the efficacy and safety of JNJ-268229 (Ultiva /Remifentanil Hydrochloride) in pediatric participants between 1 and 15 years of age during maintenance of general anesthesia.
- Trial name
- NCT01998165
- Testing
- Remifentanil
- Where
- 9 sites in Japan
- Volunteers
- 80 people
- Sponsor
- Janssen Pharmaceutical K.K.
Pediatric Rigid Bronchoscopy
Remifentanil Use in Pediatric Rigid Bronchoscopy
Purpose: In this study we wanted to compare bolus propofol and ketamine as an adjuvant to remifentanil-based total intravenous anesthesia for pediatric rigid bronchoscopy.
- Trial name
- NCT01947114
- Testing
- Propofol, Ketamine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Underdosing of Unspecified General Anesthetics
Remifentanil Minimum Effective Dose for Children Intubation Without Neuromuscular Blockade
Introduction: remifentanil's optimal dose for children intubation without neuromuscular blockade is unknown. Method: phase IV adaptative trial using Dixon's up-and-down method for modeling remifentanil's dose-response curve for…
- Trial name
- NCT02454868
- Testing
- Remifentanil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Traumatic Brain Injury
Remifentanil for Sedation of Patients With Traumatic Brain Injury (TBI)
This is a descriptive retrospective study designed to measure the efficacy of remifentanil sedation and the ability to perform frequent neurological examinations of patients with traumatic brain injuries.
- Trial name
- NCT02049320
- Testing
- Remifentanil
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Joseph D. Tobias
Anesthesia
Use of Closed-loop Anesthesia in Pediatric Patients
To compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during pediatric anesthesia
- Trial name
- LoopPed (NCT00778505)
- Testing
- Propofol, remifentanil
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Hopital Foch
Critical Illness, Pain
Population Pharmacokinetics of Remifentanil in Low-Weight Critically Ill Patients
The goal of this prospective clinical study is to learn about the population pharmacokinetics (PopPK), safety, and efficacy of remifentanil in low-body-weight patients in the Intensive Care Unit (ICU) who require mechanical…
- Trial name
- NCT07301970
- Testing
- Remifentanil
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Fudan University
Child, Only, Pain
Remifentanil Tapering and Post-adenotonsillectomy Pain in Children
Tonsillectomy is the commonest operation of childhood and results in considerable pain. Remifentanil is a potent, ultra short acting opioid with a long- established safety record in paediatric anaesthesia that is used to provide…
- Conditions
- Child, Only, Pain, Tonsillectomy, Remifentanil
- Trial name
- NCT03994146
- Testing
- Remifentanil, Sodium Chloride 9mg/mL
- Where
- 2 sites in Norway
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Analgesia
ULTIVA Post Marketing Surveillance
This study is a post-marketing surveillance to monitor safety and efficacy of remifentanil during various surgeries and identify SAEs, adverse drug reactions, and unexpected AEs not described as precautions or warnings and to…
- Trial name
- NCT01299584
- Testing
- Remifentanil
- Volunteers
- 775 people
- Sponsor
- GlaxoSmithKline
Pain Relief in Labour
A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour
Childbirth can be an extremely painful and the provision of pain relief during labour is a vital component of a positive maternal experience.
- Trial name
- RESPITE (NCT02179294)
- Testing
- Pethidine, Remifentanil
- Where
- United Kingdom
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Respiratory Distress Syndrome
Remifentanil Versus Morphine for Sedation of Premature Neonates With Respiratory Distress Syndrome
In this randomised controlled study we intended to compared intubation conditions and the continuous infusion of remifentanil (n=10) and morphine (n=10) in mechanically ventilated premature neonates (28-34wk) regarding the time…
- Trial name
- NCT00391105
- Testing
- Remifentanil
- Sponsor
- Federal University of Minas Gerais
Rhinoplasty Surgery
Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology.
- Trial name
- Effects of Dex (NCT06138574)
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital