Clinical trials: Renal Dysfunction
End Stage Renal Disease, Hemodialysis
Addition of Heparin to Taurolock-TM CLS in HD Patients With TCC Dose it Improve Catheter Patency Problems ?
Addition of Heparin to the Catheter Lock Solution (CLS): Taurolock-TM will improve the vascular patency compared to Taurolock-TM alone , in hemodialysis patients with Tunneled Cuffed Catheter(TCC) as vascular access.
- Trial name
- NCT00749619
- Testing
- Catheter Lock Solution Taurolidine and Citrate, Catheter Lock Solution :Taurolidine and Citrate and Heparin, Catheter Lock Solution : Heparin
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Fluid Overload
Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease
This study aims to verify if ethacrynic acid continuous infusion is superior to furosemide continuous infusion in total urine output production during the first 24 post operative hours.
- Trial name
- NCT01628731
- Testing
- furosemide, ethacrynic acid
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Acute Kidney Injury
Effect of Cumulative Chloride Dose on Development of Acute Kidney Injury in Critically Ill Children
The investigators would like to investigate the effect of chloride dosing on the development of acute kidney injury in critically ill patients.
- Trial name
- NCT02188602
- Where
- United States
- Sponsor
- Stanford University
Nutrition Disorders, Child
Nutritional Assessment of Children With Chronic Kidney Disease
Primary outcome is assessment of nutritional status of children with CKD. Secondary outcome is assessment STAMP screening tool for detection of malnutrition of CKD children.
- Trial name
- NCT04584905
- Testing
- dietary supplements for CKD patients
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Transplant
A Study of the Correlation Between Donor UDP-Glc and Transplanted Kidney Function
Kidney transplantation is the preferred treatment for end-stage renal disease (ESRD), however, organ shortage is the primary bottleneck restricting the progression of organ transplantation.1 Organs from Expanded Criteria Donors…
- Trial name
- NCT06707272
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qianghua Leng
Deceased Donor Kidney Transplant, Acute Kidney Injury
Deceased Donor Biomarkers and Recipient Outcomes
Compared to chronic dialysis, kidney transplantation provides recipients with longer survival and better quality of life at a lower cost.
- Conditions
- Deceased Donor Kidney Transplant, Acute Kidney Injury, Delayed Graft Function, End Stage Renal Disease
- Trial name
- DDS (NCT01848249)
- Where
- 17 sites in United States
- Volunteers
- 1,679 people
- Sponsor
- Yale University
Chronic Kidney Disease, Chronic Renal Insufficiency
Growth Hormone Treatment in Infants Aged 1 to 2 Years With Chronic Renal Insufficiency (CRI) and Growth Retardation.
This trial is conducted in Europe. Objective(s): To evaluate the effect of human growth hormone on infants aged 1 to 2 years with chronic renal insufficiency (CRI) and growth retardation despite an adequate dietary intake.
- Trial name
- NCT00184769
- Testing
- somatropin
- Where
- 20 sites in Portugal, Spain
- Volunteers
- 16 people
- Sponsor
- Novo Nordisk A/S
Pediatric Heart Transplantation, Immunosuppression
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
The TEAMMATE Trial will enroll 210 pediatric heart transplant patients from 25 centers at 6 months post-transplant and follow each patient for 2.5 years.
- Conditions
- Pediatric Heart Transplantation, Immunosuppression, Chronic Kidney Diseases, Cardiac Allograft Vasculopathy
- Trial name
- TEAMMATE (NCT03386539)
- Testing
- Everolimus, Tacrolimus, Mycophenolate Mofetil
- Where
- 25 sites in United States
- Volunteers
- 211 people
- Sponsor
- Boston Children's Hospital
RENAL INSUFFICIENCY, CHRONIC, LIVER FAILURE, ACUTE
Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant
A prospective, multisite study to evaluate the Impact of Measles, Mumps, Rubella and Varicella ProQuad® vaccination in pediatric patients 6-24 months of age who are being considered and/or evaluated for any solid organ transplant…
- Conditions
- RENAL INSUFFICIENCY, CHRONIC, LIVER FAILURE, ACUTE, HEART DISEASE
- Trial name
- ProQuad® (NCT02687763)
- Testing
- ProQuad
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
End Stage Renal Disease
Pilot Study of Taste Sensations in Patients With End-stage Renal Disease on Hemodialysis
Individuals on dialysis due to kidney failure have very prescriptive diets. These diets help increase dialysis effectiveness and help patients control blood levels of electrolytes including potassium and phosphate, acid-base…
- Trial name
- NCT03495271
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Purdue University
Acute Kidney Injury
Incidince of Acute Kidney Injury in Children With Community Acquired Pneumonia at Assiut University Children Hospital
Descriptive prospective observational study of Incidince of acute kidney injury in children with community acquired pneumonia at assiut university children hospital
- Trial name
- NCT06117826
- Volunteers
- 100 people
- Sponsor
- Assiut University
Renal Insufficiency, Acute Kidney Injury
Influence of Perioperative Kidney Function on Postoperative Outcome
This study investigates the influence of perioperative changes in serum creatinine on hospital length of stay and mortality.
- Trial name
- NEPHRANEST (NCT01522313)
- Where
- Germany
- Volunteers
- 39,369 people
- Sponsor
- Charite University, Berlin, Germany
Cardiovascular Diseases, Diabetes Mellitus
Determinants of Cardiovascular Disease, Kidney Disease and Diabetes
Cardiovascular disease (CVD), chronic kidney disease (CKD), diabetes mellitus (DM) and HIV infection are long-term conditions (LTC) with major health implications for people of African ancestry.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- NCT04646408
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Critical Illness, Acute Kidney Injury
Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure
The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Systemic Inflammatory Response Syndrome
- Trial name
- NCT04033224
- Testing
- Commercial membrane for Extracorporeal Blood Purification Therapy (EBPT)
- Where
- 15 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Careggi Hospital
Chronic Kidney Disease, Sarcopenia
Effect of Ketosteril on Sarcopenia in Patients With Chronic Kidney Disease
The investigators hypothesize that Ketosteril can improve sarcopenia in patients with renal disease without increasing the burden on the kidneys and causing deterioration of renal function.
- Trial name
- NCT06329622
- Testing
- low-protein diet + Ketosteril, low-protein diet
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Huashan Hospital
End-Stage Renal Disease
Once Daily Dosing to Improve Medication Adherence and Patient Satisfaction in Kidney Transplant Recipients
Patient failure to take medications as prescribed (medication non-adherence) is now identified as an important cause of kidney transplant failure.
- Trial name
- OnceDaily (NCT02426502)
- Testing
- Conversion to Advagraf, conversion of non-immunosuppressant drugs to once daily, Conversion to once daily MPA
- Where
- 3 sites in Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Kidney Disease(CKD)
Functional Capacity in Children with Chronic Kidney Disease
The aim of our study is to assess the functional capacity of children with chronic kidney disease using various tests.
- Trial name
- NCT06683339
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Acute Kidney Injury
The Effect of Renastart Formula Supplementation in Children With Acute Kidney Injury in Maintaining Normal Serum Electrolytes Levels
This clinical trial will evaluate Renastart formula effectiveness in children with acute kidney injury (AKI) and acute on top of chronic kidney disease (CKD), in maintaining normal serum electrolytes levels without using…
- Trial name
- NCT06218212
- Testing
- Renastart formula, calcium carbonate (phosphorus binder) with / or sodium polystyrene sulfonate (potassium binder) with dosage 0.5-1mg/kg/day orally.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Renal Failure
Caudal Epidural Catheterization in Pediatric Renal Transplant: Effect on Hemodynamics and Pain After Surgery
pain control in pediatric renal transplant is a major concern. the main goal during anesthesia of renal transplant in pediatrics is to maintain hemodynamics in a range close to that of the adult donor.
- Trial name
- NCT02037802
- Testing
- B-Braun, Perifix® ONE Paed, Germany, Pethidine, Propofol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Perspective of Healthcare Professionals Haemodialysis Needling, Dialysis
Behind the Needle: Healthcare Professionals' Perspectives on HD Needling
Haemodialysis is essential for patients with End-Stage Renal Disease (ESRD), requiring consistent vascular access through arteriovenous fistulas or grafts.
- Trial name
- NCT06845605
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- East and North Hertfordshire NHS Trust