Clinical trials: Reproductive Effects
Effects of Chemotherapy
The Longitudinal Ovarian Reserve Study
Postmenarchal female cancer patients scheduled to undergo cancer therapy may enroll in this study to assess changes in existing and novel surrogate measures of fertility potential before, during and after chemotherapy.
- Trial name
- NCT02395341
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Assisted Reproductive Technology
Effect of Assisted Reproductive Technology on Cardiac Development in Childhood Assessed by Echocardiography
Assisted reproductive technology (ART) has extensively allowed pregnancy for infertile couples. However, the long-term effect of ART exposure on cardiovascular development and potential association with ART procedure and parental…
- Trial name
- Heart and ART (NCT02190422)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Contraceptive Usage, Diffuse Noxious Inhibitory Control
Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women
The purpose of this study is tu assess the influence of oral contraceptives (OC) on diffuse noxious inhibitory control (DNIC) in healthy women, tested during high, low endogenous estrogens sessions and ovulatory period.
- Trial name
- NCT04365426
- Testing
- Mechanical stimulus, Thermal (cold) stimulus, Oral contraceptive (OC)
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Vina del Mar
Assisted Reproductive Treatments
Scenario-Based Hybrid Simulation for Patient Education in Assisted Reproductive Treatment
This study aims to evaluate the effect of a scenario-based hybrid simulation designed for patient education in assisted reproductive treatment on nursing students' anxiety, effective communication, self-efficacy, knowledge, and…
- Trial name
- NCT07851155
- Testing
- Scenario-Based Hybrid Simulation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duzce University
Epilepsy
Effect of Valproate Versus Levetiracetam Monotherapy on Reproductive Functions in Epileptic Males
Background: Different antiepileptic drugs are responsible for reproductive dysfunction in male epileptic patients. The aim of this study is to evaluate the effect of valproate versus levetiracetam as a monotherapy on males' sex…
- Trial name
- NCT03953781
- Testing
- Effect of valporate on Reproductive Functions in Newly Diagnosed Epileptic Males, Effect of levetiracetam on epileptic males reproductive function
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Adolescents, Anemia
Effect of Micronutrients and Life Skills Education on the Health and Nutrition of Adolescent and Young Women in Pakistan
The primary aims of this study are: 1) To evaluate the impact of supplementation with multiple micronutrients (MMN) from preconception and life skills education among women 15-18.9 years of age at enrolment on the prevalence of…
- Conditions
- Adolescents, Anemia, Pregnancy, Empowerment
- Trial name
- NCT03287882
- Testing
- Multiple micronutrients (UNIMMAP composition), Life skills based education
- Where
- Pakistan
- Volunteers
- 25,447 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Healthy, Deficiency Disease
Effects of Dietary Carbohydrate and Fat on Hormones
This study will try to determine if intake of dietary fats or carbohydrates influences the tendency to gain weight or accumulate body fat.
- Trial name
- NCT00016848
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy Malaria, Bacterial Vaginoses
The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract
Malaria in pregnancy has devastating consequences for mother and foetus. WHO recommends intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) for asymptomatic women, but high-level parasite…
- Conditions
- Pregnancy Malaria, Bacterial Vaginoses, Trichomonas Vaginitis
- Trial name
- NCT04189744
- Testing
- IPTp-sulphadoxine-pyrimethamine plus metronidazole, IPTp-dihydroartemisinin-piperaquine plus metronidazole, IPTp-sulphadoxine-pyrimethamine
- Where
- Zambia
- Volunteers
- 5,436 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Family Planning
Effects of Family Planning Education Given to Illiterate Women Via Visual Material Support
This study was conducted to determine the effects of family planning education given to married illiterate women of reproductive age via visual material support on their family planning attitudes and contraceptive preferences.in…
- Trial name
- NCT06755749
- Testing
- Family Planning Education
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Inonu University
Breast Cancer, Breast Self-Examination
Training On Self-Breast Examination Using Visual Breast Examination Materials For İlliterate Women.
Breast cancer is the most common malignancy among women and remains a major public health concern despite being largely preventable through early detection and regular screening practices.
- Trial name
- NCT07692464
- Testing
- Visual-based Breast Self-Examination (BSE) Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Inonu University
Sperm Count, Low, Reproductive Sterility
A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome
The investigators plan to retrospectively analyze clinical data from 14,189 fresh ICSI cycles in Reproductive and Genetic Hospital of CITIC-Xiangya from January 2016 to December 2017.The investigators will regard total…
- Trial name
- NCT03594201
- Testing
- semen pretreatment
- Where
- China
- Volunteers
- 12,215 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Adolescent Behavior, Sexual Behavior
Assessing the Preliminary Effects of a Multisectoral Agricultural Intervention on Adolescent Girls' Health
The goal of this study is to understand how the Shamba Maisha household agricultural and economic intervention impacts the sexual, reproductive, and nutritional health of adolescent girls.
- Conditions
- Adolescent Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- NCT03741634
- Testing
- Multi-sectoral agricultural intervention
- Where
- 16 sites in Kenya
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy
Michigan Contraceptive Access, Research, and Evaluation Study Children: Phase 1
This project builds on the Michigan Contraceptive Access Research and Evaluation Study (M-CARES) to evaluate the long-term effects of mothers' access to free contraceptives and reductions in unintended pregnancies on their…
- Trial name
- M-CARES-K (NCT04371900)
- Testing
- Mother receives voucher valued at 100% of cost of name-brand IUD (March 4, 2019-March 31, 2023), Mother receives voucher valued at 50% of cost of name-brand IUD (August 26, 2018-March 3, 2019)
- Where
- 9 sites in United States
- Volunteers
- 4,700 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sexually Transmitted Infection (STI), HIV
Assessing the Effects of a Multisectoral Agricultural Intervention on the Reproductive and Sexual Health of Adolescent Girls and Young Women
In Kenya, HIV incidence among adolescent girls and young women (AGYW) ages 15-24 years is 1-2 per 100 person-years and approximately 30% of AGYW have had at least one sexually transmitted infection (STI).
- Conditions
- Sexually Transmitted Infection (STI), HIV, Food Insecurity, Mental Health
- Trial name
- Vijana Shamba (NCT06953310)
- Where
- Kenya
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception, Contraceptive Usage
Advance Provision of Postpartum Emergency Contraception and Its Effects on Reproductive Autonomy
This study will entail provision of ulipristal acetate (UPA) for emergency contraception (EC) in the postpartum period for patients who have not chosen to initiate a highly effective form of contraception and study the use of EC…
- Conditions
- Contraception, Contraceptive Usage, Reproductive Issues
- Trial name
- NCT05285605
- Testing
- Ulipristal Acetate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Breast Cancer, Psychosocial Effects of Cancer and Its Treatment
Assessing Women's Attitudes About the Risk of Infertility Related to Adjuvant Therapy for Early Breast Cancer
RATIONALE: Adjuvant therapy given after surgery for early breast cancer may cause infertility. Assessing young women's attitudes and feelings about the risk of infertility may help improve the ability to plan effective treatment.
- Conditions
- Breast Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction and Infertility, Sexuality and Reproductive Issues
- Trial name
- NCT00062400
- Testing
- psychosocial assessment and care
- Where
- 27 sites in Belgium, Chile and 13 more
- Volunteers
- 385 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC