Clinical trials: Respiratory Function
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study was to see if a brief delay in cord clamping for 30 to 45 seconds would result in higher hematocrit levels, fewer transfusions, healthier lungs, and better motor function at 40 wks and 7 months of age.
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis
- Trial name
- NCT00840983
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rhode Island
Hemoglobin SC Disease
Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease
Sickle cell disease (SCD), also known as sickle cell anemia, is an inherited blood disease that can cause intense pain episodes. Hemoglobin SCD (HbSC) is a form of SCD that is characterized by dense red blood cells.
- Trial name
- NCT00532883
- Testing
- Hydroxyurea, Magnesium Pidolate
- Where
- 19 sites in United States
- Volunteers
- 44 people
- Sponsor
- St. Jude Children's Research Hospital
Sleep Apnea
A Community Pharmacist-led Intervention to Improve Screening of Sleep Apnea in Primary Care
The purpose of this study is to evaluate the feasibility and the effectiveness of sleep apnea screening program for patients at risk in community pharmacies.
- Trial name
- NCT01552083
- Testing
- screening of sleep apnea
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Noninvasive Positive Pressure Ventilation;, Sedation;
Interventional Bronchoscopy Under Noninvasive Ventilation
To evaluate the effect and safety of noninvasive ventilation assisted interventional bronchoscopy for hypoxemia patients with central airway stenosis.
- Conditions
- Noninvasive Positive Pressure Ventilation;, Sedation;, Bronchoscopy；, Interventional；
- Trial name
- NCT02289586
- Testing
- invasive ventilation, interventional bronchoscopy, noninvasive ventilation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Futian People's Hospital
Cystic Fibrosis
Modeling of Chest Physiotherapy Using Impedance Measurements (PHYSIOMOD)
"The usefulness of respiratory physiotherapy and its execution modalities remains highly debated even though reviews of the literature show that respiratory physiotherapy is able to improve the drainage of bronchial secretions…
- Trial name
- PHYSIOMOD (NCT04094441)
- Testing
- chest physiotherapy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastrointestinal Disease, Esophageal Cancer
PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide
The goal of this clinical research study is to use a new breathing test that measures the amount of nitric oxide (NO) you exhale.
- Conditions
- Gastrointestinal Disease, Esophageal Cancer, Lung Cancer
- Trial name
- NCT00867477
- Testing
- Breathing Test, Respiratory Symptoms Questionnaire, Pet Scan
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- M.D. Anderson Cancer Center
Lysosomal Storage Disease, Lung Diseases
Biomarker for Maroteaux-Lamy Disease (BioMaroteaux)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Maroteaux-Lamy disease from blood
- Conditions
- Lysosomal Storage Disease, Lung Diseases, Obstructive Sleep Apnoea, Macroglossia
- Trial name
- BioMaroteaux (NCT01458613)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
Copd, COVID-19
Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19
The purpose of this research project is to study small airways physiological function in patients with chronic obstructive lung disease or COVID-19 and explore the relationship with in-vivo microanatomical small airway structure…
- Conditions
- Copd, COVID-19, Asthma, Small Airways Disease
- Trial name
- PASSPORT (NCT04716023)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Imperial College London
Moderate Respiratory Distress, Severe Respiratory Distress
High Flow Nasal Oxygen Therapy an Implementation Study in Pediatric Wards
The purpose of this study is to prospectively evaluate the process of implementing HFNO in several MSF projects, varying according to geographical and programmatic contexts, population, health structures, human resources, and…
- Trial name
- HFNO (NCT06715423)
- Where
- Afghanistan
- Volunteers
- 960 people
- Sponsor
- Epicentre
Respiratory Distress Syndrome, Adult, Lung Diseases
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
The purposes of this study are to assess rapidly innovative treatment methods in patients with adult respiratory distress syndrome (ARDS) as well as those at risk of developing ARDS and to create a network of interactive Critical…
- Trial name
- NCT00000579
- Testing
- Low Tidal Volume Ventilation, Positive End-Expiratory Pressure, Lysofylline
- Where
- 21 sites in United States, Canada
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Mechanical Ventilation for More Than 48 Hours.
Chlorhexidine Gluconate for Prevention of Ventilator Associated Pneumonia in Children.
To determine the efficacy of prophylaxis with 0.12% chlorhexidine gluconate compared with placebo to prevent ventilator associated pneumonia in children admitted to a pediatric critical care unit.
- Trial name
- NCT01883596
- Testing
- 0.12% chlorhexidine solution
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Sinaloa Pediatric Hospital
Lung Surgery
The Effect of Breathing Exercises on Pain, Anxiety, Dyspnea, and Insomnia in Patients Undergoing Lung Surgery.
Surgical treatment is performed with the aim of reducing, halting the progression of, or treating certain pathological conditions in the human body by removing some tissue or organs from the body.
- Trial name
- NCT06460259
- Testing
- Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- KTO Karatay University
Respiratory Disease, Children, Only
Kinshasa Lung Ultrasound Approach Validation
Study team will perform a prospective, observational study in two sites in the Democratic Republic of Congo (DRC) and Bangladesh in children aged 3 months to 14 years, admitted to hospital with acute respiratory symptoms.
- Trial name
- K-LUS (NCT06839963)
- Where
- 3 sites in Bangladesh, Democratic Republic of the Congo and 1 more
- Volunteers
- 178 people
- Sponsor
- University of Oxford
Lateral Sinus Thrombosis, Mastoiditis
Otogenic CSVT Retrospective Case Series and Associated Thrombophilia
The aim of this study is to report the clinical presentation, Microbiological, laboratory and imaging evaluation, prothrombotic factors analysis, medical and surgical management and outcomes in children with Otogenic Cerebral…
- Conditions
- Lateral Sinus Thrombosis, Mastoiditis, Otitis Media
- Trial name
- CSVT PCR (NCT03864055)
- Where
- Israel
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Vitamin D3 Deficiency, Prematurity
Vitamin D and Health Outcomes in Preterm Born Population
Improved survival of very preterm newborn population during the last decades has challenged us neonatologists to study and improve nutritional practices including vitamin D (VitD) supplementation.
- Conditions
- Vitamin D3 Deficiency, Prematurity, Lung Diseases, Heart Rate Variability
- Trial name
- ViDePrePop (NCT04342078)
- Testing
- Vitamin D
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Mechanical Ventilation Complication
Assessing Gas Exchange in Intensive Care Patients on a Ventilator
In an attempt to standardise the degree of impairment of gas exchange in the lungs of ICU patients a number of indices of oxygen exchange have been developed.
- Trial name
- NCT02599350
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Aberdeen
Asthma in Children
Safety and Feasibility of a Novel Device for Assessing Respiratory Function in Children
This is an early phase pilot study designed to test the safety and feasibility of using a novel, wireless, wearable device (Leo) for assessing respiratory parameters (lung volume, respiration rate, heart rate and indices related…
- Trial name
- NCT04873193
- Testing
- Leo device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- ResMed
Respiratory Distress Syndrome, Preterm Pregnancy
Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants
The aim of this study is to see if giving less invasive surfactant administration (LISA) during high-flow nasal cannula (HFNC) oxygen treatment reduces the need for invasive ventilation in babies with breathing problems born 2-6…
- Conditions
- Respiratory Distress Syndrome, Preterm Pregnancy, Surfactant Deficiency Syndrome Neonatal
- Trial name
- NCT06421506
- Testing
- Less invasive surfactant administration during high flow nasal cannula treatment
- Where
- United Kingdom
- Volunteers
- 245 people
- Sponsor
- King's College Hospital NHS Trust
Bronchiolitis Obliterans
Lung Function, LCI, Bronchial Inflammation and Epigenetics of Patients With BO
Bronchiolitis obliterans is a chronic disease in which a persistent inflammatory process leads to obliteration of the small airways.
- Trial name
- FRABO-03 (NCT02627833)
- Testing
- observation
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Volume-Controlled Ventilation, Pressure-Controlled Ventilation Volume Guaranteed
Volume-Controlled Ventilation and Pressure-Controlled Ventilation Volume Guaranteed in Obese Patients in Laparoscopic-Assisted Surgery
The aim of this study is to compare the efficacy of the pressure controlled ventilation volume-guaranteed (PCV-VG) versus volume-controlled ventilation (VCV) modes as regards lung compliance and oxygenation index in obese…
- Conditions
- Volume-Controlled Ventilation, Pressure-Controlled Ventilation Volume Guaranteed, Obese, Laparoscopy
- Trial name
- NCT06117748
- Testing
- Pressure controlled ventilation-volume guaranteed, Volume controlled ventilation
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
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