Clinical trials: Respiratory Function
Obstructive Sleep Apnea of Child
Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.
Sleep disordered breathing (SDB) is a common disease in both adults and children and is caused by the obstruction of the upper airway during sleep.
- Trial name
- NCT02247167
- Testing
- adenotonsillectomy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Roma La Sapienza
Noninvasive Ventilation
NHFOV Vs NIPPV Post-extubation in Preterm Neonates
comparison between Noninvasive Intermittent Positive Pressure Ventilation (NIPPV) and Noninvasive High Frequency Oscillation Ventilation (NHFOV) post-extubation in preterm neonates as regards the efficacy and their possible…
- Trial name
- NCT06620107
- Testing
- noninvasive high frequency oscillation ventilation, noninvasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kafrelsheikh University
Cough, Upper Respiratory Tract Infection
Comparison of Efficacy and Tolerability of Two Cough Syrups in Cough Due to Cold in Children.
The purpose of this study is to determine if there is comparable efficacy between carbocisteine and a protective cough syrup from natural ingredients in children's cough due to upper respiratory tract infections (URTI) such as…
- Trial name
- URTI (NCT01968434)
- Testing
- protective cough syrup, carbocisteine cough syrup
- Where
- 4 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Clalit Health Services
Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes
A CFit Study - Baseline
A great medical success is the increase in the median survival age associated with cystic fibrosis (CF). However, this success has led to a new era of research with the aim to maximise the quality of life (QoL) of the aging CF…
- Trial name
- NCT03234387
- Testing
- No intervention - only assessments.
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Effect of Breastfeeding on Maternal and Child Health Outcomes
Promotion of Breastfeeding Intervention Trial
The overall goal of the PROBIT study is to investigate the influence of a randomized breastfeeding promotion intervention designed to increase the duration and exclusivity of breastfeeding ("the breastfeeding promotion…
- Trial name
- PROBIT (NCT01561612)
- Testing
- Breastfeeding promotion and support
- Where
- Belarus
- Volunteers
- 17,046 people
- Sponsor
- Harvard Pilgrim Health Care
Respiratory Failure
Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care
The purpose of this study is to determine whether a computer-driven system (Smartcare/PS) decreases weaning duration from mechanical ventilation when compared to usual care in children.
- Trial name
- NCT00678912
- Testing
- Smartcare/PS
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- St. Justine's Hospital
Chronic Obstructive Pulmonary Disease
The Effects of a Positive Expiratory Pressure (PEP) on Dyspnea and Dynamic Hyperinflation During Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients
From the relationship between pathophysiology of chronic obstructive pulmonary disease (COPD), dyspnea, and dynamic hyperinflation during ventilatory increasing, the investigators hypothesize that 1.
- Trial name
- NCT00741832
- Testing
- Conical Positive Expiratory Pressure Device (C-PEP), Control breathing
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Ventilator Associated Pneumonia (VAP)
Pulmonary Infections and Barotrauma Associated With MV IN PICU
This study aims to determine the incidence, risk factors and outcome of ventilation associated common complication in the PICUs at Assiut University Children Hospital in Egypt.
- Trial name
- NCT05792501
- Testing
- Mechanical ventilation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea
Rapid Maxillary Expansion for Residual Pediatric
Randomized Controlled Trial comparing Rapid Maxillary Expansion with Standard Clinical Practice in patients with residual pediatric Obstructive Sleep Apnea Syndrome after adenotonsillectomy.
- Trial name
- ERMES (NCT02947464)
- Testing
- Standard clinical practice, Standard clinical practice + Rapid Maxillary Expansion
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Pulmonary Arterial Hypertension
Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies
A surveillance of respiratory tract related adverse events in patients treated with Tyvaso®(treprostinil) Inhalation Solution versus other FDA approved therapies
- Trial name
- Aspire (NCT01266265)
- Testing
- inhaled prostacyclin, prostacyclin, subcutaneous and intravenous prostacyclin
- Where
- 88 sites in United States
- Volunteers
- 1,333 people
- Sponsor
- United Therapeutics
Accident Caused by Snow Avalanche
Physiological Values When Breathing in an Air-pocket. Mountain Lab 2019 (ML2019)
The literature describes and report neurologic intact patients surviving an avalanche several hours after they were buried. The most important factor for surviving more than 15-35 min of burial is considered to be the presence of…
- Trial name
- NCT03911011
- Testing
- Fresh air
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Cough, Acute
Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough
Cough is the most bothersome symptom for patients with the common cold. The objective of the study is to compare the phytotherapic "Bromelin", a compound preparation of honey from the bee apis mellifera with the extract of the…
- Trial name
- BROMETOSS (NCT01356693)
- Testing
- Bromelin
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- Universidade Federal de Pernambuco
Acute Respiratory Distress Syndrome
Dead Space and Inhaled Nitric Oxide in Pediatric Acute Respiratory Distress Syndrome
The goal of this observational study is to determine whether a marker of dead space (the end-tidal to alveolar dead space fraction [AVDSf]) is more strongly associated with mortality risk than markers of oxygenation abnormality…
- Trial name
- DiNO (NCT06690801)
- Where
- 10 sites in United States
- Volunteers
- 1,260 people
- Sponsor
- Children's Hospital Los Angeles
Sleep Apnea, Adenotonsillectomy
Pain at Home After Tonsillectomy With or Without Adenoidectomy
The study type is a prospective observational cohort study of children undergoing adenotonsillectomy (T\&A). The study will recruit the annual caseload of children undergoing T\&A at the Montreal Children's Hospital, QC, Canada…
- Conditions
- Sleep Apnea, Adenotonsillectomy, Pediatric ALL
- Trial name
- NCT03378830
- Where
- Canada
- Volunteers
- 319 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Acute Respiratory Distress Syndrome, Acute Lung Injury
Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS)
Study of the long term outcomes and economic impact of the pulmonary artery catheter in acute respiratory distress syndrome (ARDS/ALI) patients.
- Conditions
- Acute Respiratory Distress Syndrome, Acute Lung Injury, Lung Diseases
- Trial name
- NCT00234767
- Testing
- Pulmonary Artery Catheter, Protocolized Fluid Management
- Volunteers
- 650 people
- Sponsor
- University of Pittsburgh
Adolescent Idiopathic Scoliosis
Pilates-Based Exercises Practised by Hybrid Telerehabilitation in Adolescent Idiopathic Scoliosis
The aim of this study was to see the effect of pilates-based exercise training applied with hybrid telerehabilitation method on Cobb angle, trunk rotation angle (ATR), respiratory functions, respiratory muscle strength and…
- Trial name
- NCT05761236
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Bezmialem Vakif University
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Respiratory Failure
Impact of Cannulation Strategy on Neurologic Injury in Infants With Respiratory Failure
There has been increasing use of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for infants with respiratory failure, up to 92% of neonatal respiratory support in 2021.
- Trial name
- NCT06079034
- Testing
- Venovenous ECMO, Venoarterial ECMO
- Where
- United States
- Volunteers
- 5,058 people
- Sponsor
- University of Michigan
Patients With Suspected Non-small Cell Lung Cancer (NSCLC) at Clinical Stage T1
Anesthesia Comparison in Early-stage Small NSCLC: A Multicenter RCT
This study is a prospective, randomized, controlled study, which intends to enroll patients with suspected early-stage NSCLC (non-small cell lung cancer) with a diameter of ≤ 3 cm as research subjects.
- Trial name
- NCT07327736
- Testing
- Non-intubated video-assisted thoracic surgery with spontaneous breathing (NIVATS)
- Volunteers
- 410 people
- Sponsor
- Tang-Du Hospital
Trauma, Cardiac Arrest
Airway Management Study in Physician Manned Helicopter Emergency Medical Services
An international airway management expert group has recently developed an Utstein-style template for uniform reporting of data from prehospital advanced airway management.
- Conditions
- Trauma, Cardiac Arrest, Emergencies
- Trial name
- AIRPORT (NCT01502111)
- Where
- Norway
- Volunteers
- 2,333 people
- Sponsor
- Norwegian Air Ambulance Foundation