Clinical trials: Restoration
Dental Caries in Children
Clinical and Radiographic Evaluation of Injectable Composite Versus Packable Composite in Restoring of Primary Molars
This randomized clinical trial aims to compare the clinical and radiographic performance of injectable composite versus packable composite in restoring cavitated primary molars in children aged 4 to 8 years.
- Trial name
- NCT07239154
- Testing
- packable composite, injectable composite
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Eslam samy abdel monaem kalboush
Dental Caries
Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars
This protocol aims to assess the cost-efficacy and applicability of the treatment of lesions moderate caries using sealants as an alternative to the restorations on occlusal surfaces of deciduous teeth.
- Trial name
- NCT03005405
- Testing
- Ionomer Restoration (control), Ionomer Sealant (test), Oral hygiene orientation and professional fluoride application
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- University of Sao Paulo
Oral Health
Clinical Study of Antibacterial Nanoparticles Incorporated in Composite Restorations
Resin composites withholding antibacterial properties may be useful in preventing recurrent caries. Covalently attached antibacterial polymers are a possible solution.This in vivo study would evaluated the antibacterial effect of…
- Trial name
- NCT00299598
- Testing
- alkylated polyethylenimine nanoparticles antibacterial evaluation
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries
Clinical Performance of Bioactive Highly Filled Injectable Flowable Composite for Direct Posterior Occlusal Conservative Restorations Using FDI Criteria: Two Year Randomized Clinical Trial
The aim of this study is to evaluate Clinical Performance of bioactive highly filled injectable flowable composite for direct posterior occlusal conservative restorations using FDI Criteria
- Trial name
- NCT06790511
- Testing
- bioactive highly filled injectable flowable composite, highly filled injectable flowable composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bite Force, Masseter Muscle
Postoperative Bite Force After Bioflx and Zirconia Crowns in Children
This randomized clinical trial aims to compare postoperative bite force following full-crown restoration with preformed Bioflx and zirconia crowns in children undergoing comprehensive dental treatment under general anesthesia.
- Conditions
- Bite Force, Masseter Muscle, Zirconia Crowns, Primary Molars
- Trial name
- NCT07825103
- Testing
- Preformed Bioflx Crown, Preformed Zirconia Crown
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dental Caries in Children
Aesthetic Restorations in Deciduous Anterior Teeth
This study proposes to conduct a randomized clinical trial (RCT), composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified ICDAS C+ score, with involvement of more than two…
- Trial name
- NCT05875064
- Testing
- Restoration with resin composite and polyvinyl crown, Restoration with conventional resin composite
- Volunteers
- 194 people
- Sponsor
- University of Nove de Julho
Molar Hypomineralization, Dental Restoration Failure of Marginal Integrity
CAD-CAM or Adhesive Approaches for MIH Treatment
Aim: This randomized controlled clinical study aimed to compare direct composite resin restorations and Computer Aided Design-Computer Aided Manufacturing (CAD-CAM) supported inlay or onlay restorations in young permanent molar…
- Trial name
- NCT06456619
- Testing
- Tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baskent University
Composite Resins
Clinical Evaluation of Posterior Direct Restoration in Adolescents
The present study aims to evaluate the performance of direct restorations with bulk fill resins in molars with great structural loss, with endodontic treatment.
- Trial name
- NCT03936855
- Testing
- Direct composite resin
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Renata Afonso da Silva Pereira
Partial Dentin Caries Removal
Radiographic Assessment of Glass Ionomer Restorations With and Without Prior Application of Nano Silver Fluoride in Occlusal Carious Molars Treated With Partial Caries Removal Technique
eligible teeth will be randomly divided into two groups to be treated with incomplete caries excavation (A), where (A1) represents teeth to be treated with application of Nano silver fluoride solution on remaining carious dentin…
- Trial name
- NCT03193606
- Testing
- nano silver fluoride solution
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Restoration of Permanent Molars Affected With (MIH) Using Composite Restorations or Preformed Metal Crowns
The aim of this study is to compare clinical outcome of using direct esthetic composite restorations in managing MIH cases and the use of preformed metal crowns.
- Trial name
- NCT04658602
- Testing
- Preformed stainless steal crown cemented by glass ionomer lutting cement (Ketac cem,3M Espe)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nada Mahmoud Abd El-Azim Mohamed
Dental Caries
Clinical Performance of Posterior Glass Ionomer Restorations in Adolescents (KETAC)
The purpose of this study is to determine whether two tooth-colored glass ionomer materials are effective for load-bearing dental fillings.
- Trial name
- NCT02705729
- Testing
- Ketac Universal, Ketac Molar Quick
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Caries; Dentin, Dental Restoration Failure of Marginal Integrity
Absence of Liner Following the Selective Caries Removal (ALFSCaRe)
This randomized, multi-centric, controlled clinical trial will assess the effectiveness of a simplified restorative protocol used after the selective carious tissue removal in posterior teeth presenting deep carious lesions.
- Trial name
- (ALFSCaRe) (NCT03933176)
- Testing
- Restoration of carious lesions
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dental Caries Extending Into Dentine
Digital Subtraction Radiography Evaluation of SMART Restoration With Partial Caries Removal in Primary Teeth
The objective of this study was to analyze the radiographic density of digital subtraction radiographs after SMART restoration with partial caries removal in primary molars at 6 and 12 months.
- Trial name
- DSR (NCT01749267)
- Testing
- partial caries removal only at enamel dentin junction.
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Junctional Epidermolysis Bullosa Non-Herlitz Type
Open-label, Pivotal Clinical Trial to Confirm Efficacy and Safety of Autologous Grafts Containing Stem Cells Genetically Modified for Epidermis Restoration in Patients With Junctional Epidermolysis Bullosa
Prospective, multicenter and multinational, open-label, uncontrolled clinical study to assess the safety and efficacy of autologous cultured epidermal grafts containing epidermal stem cells genetically modified transduced with a…
- Trial name
- HOLOGENE 5 (NCT05111600)
- Testing
- Transplantation
- Where
- 2 sites in France, Italy
- Volunteers
- 2 people
- Sponsor
- Holostem s.r.l.
Dental Carious, Dental Filling
Clinical Evaluation of Esthetic Restorations Placed in Primary Molars With Composite Resin Enriched With Insoluble Anti Bacterial Nano Particles
Composite resins are presently among the most popular esthetic restorative materials in dentistry. These materials offer excellent esthetic appearance, allow for conservative cavity preparation and are now becoming widely…
- Trial name
- IABN (NCT00389714)
- Testing
- dental restoration
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries, Tooth Decay
Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar Teeth
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary molar teeth. The two different materials of crowns are resin polymer and stainless steel crowns.
- Trial name
- NCT06354634
- Testing
- Resin polymer (NuSmile Bioflx) crown, Stainless steel crown
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Virginia Commonwealth University
Molar Incisor Hypomineralization
Comparing CAD/CAM vs Composite for Carious Hypomineralized Molars Evaluating Clinical Outcomes of Both Treatments.
Molar Incisor Hypomineralization (MIH) is enamel hypomineralization defined as qualitative defects caused by disruptions in either the calcification or maturation phases of amelogenesis affecting one or more first permanent…
- Trial name
- NCT07049016
- Testing
- restoring the MIH affected young permanent molars using Direct nanohybrid flowable composite, restoring the MIH affected young permanent molars using IPS e.max CAD
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous Local Anesthesia System in Children With Molar Incisor Hypomineralization
The goal of this clinical trial is to compare in effectiveness of intraosseous anesthesia and inferior alveolar block anesthesia in children with molar incisor hypomineralization (MIH).
- Conditions
- Molar Incisor Hypomineralization, Hypersensitivity, Composite Restoration
- Trial name
- NCT06461143
- Testing
- %4 articaine with 1:200 000 adrenaline
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University