Clinical trials: Roux-en-y Gastric Bypass
Gastric Bypass Surgery
The Effects of Probiotic Supplementation on the Results of Gastric Bypass Surgery
In this study, patients undergoing the bariatric surgery will be assigned to take either probiotic capsules or placebos from 1 month before surgery to 3 months after the surgery.
- Trial name
- NCT02708589
- Testing
- probiotic
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- National Nutrition and Food Technology Institute
Severe Obesity
Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass
The purpose of this study is to examine the effects of bile acid and bile acids sequestrants on GLP-1 Secretion, during a meal, in patients after Roux-en-Y gastric bypass.
- Trial name
- NCT02876484
- Testing
- Colesevelam, Chenodeoxycholic Acid, Water
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Hvidovre University Hospital
Diabetes Mellitus, Type 2, Obesity
Effect of Roux-en-Y Gastric Bypass or Gastric Sleeve Surgery on Type 2 Diabetes
Roux-en-Y Gastric Bypass surgery (RYGB) ameliorates type 2 diabetes within days after surgery. Studies indicate that the gastric sleeve procedure has comparable effect on type 2 diabetes, but to what extent and how is not fully…
- Trial name
- NCT02713555
- Testing
- Roux-en-Y Gastric Bypass, Gastric Sleeve
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative
Antireflux Suture In One Anastomsis Gastric Bypass
To prevent refulx symptoms in a type of bariatric surgery, a suture is taken.there is no enough evidence in support of or against the suture.
- Trial name
- NCT07148492
- Testing
- Antireflux suture, No Antireflux suture
- Where
- Pakistan
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
Obesity, Morbid
4XL Study - Obesity Surgery in Adolescence
The purpose of this study on adolescents between 13 and 18 years of age with morbid obesity is to determine whether surgical treatment gives more health benefits than standard conservative treatment, and if laparoscopic gastric…
- Trial name
- 4XL (NCT00923819)
- Testing
- Laparoscopic gastric bypass, Standard conservative treatment
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset i Vestfold HF
Obesity and Obesity-related Medical Conditions, Weight Regain
The Application of Gastric Bypass Stents in Patients with Weight Regain After Laparoscopic Sleeve Gastrectomy：a Feasibility Study
This study is based on the National Center for Integrated Traditional Chinese and Western Medicine, utilizing the centralized advantages of our department and integrating multiple disciplines (general surgery, endocrinology…
- Trial name
- DJBL for LSG (NCT06801496)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Obese Adolescents
Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries
Determine the short and long term safety and efficacy of the Gastric bypass , laparoscopic sleeve gastrectomy, and Gastric banding (LAGB) on severely obese adolescents.
- Trial name
- NCT02004561
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Obesity
Adolescent Gastric By-pass and Diabetic Precursors
The purpose of this research study is to find out what effects (good and bad) gastric bypass has on metabolism, including pancreatic insulin secretion.
- Trial name
- NCT00360373
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Morbid Obesity Requiring Bariatric Surgery
Can Pre-operative Lean Mass Predict Weight Loss After Roux-en-Y Gastric Bypass?
The goal of this observational study is to evaluate whether preoperative fat-free mass predicts post-operative weight loss in patients undergoing Roux-En-Y gastric bypass.
- Trial name
- FLAG (NCT07565051)
- Where
- Switzerland
- Volunteers
- 91 people
- Sponsor
- University Hospital, Geneva
Small Intestine Length Measurement
Digital 3D Reconstruction Predicts Small Bowel Length
The prevalence of type 2 diabetes mellitus (T2DM) has been increasing annually worldwide, and the prevalence of diabetes has reached 11.6% in China.
- Trial name
- DTDRPSBL-BS (NCT05338567)
- Testing
- Small intestine length measurement method
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Morbid Obesity
Probiotics Improve Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass: A Prospective Randomized Trial
Obesity has been a global epidemic. Currently, bariatric surgery has been recognized as the only successful treatment for morbid obesity.
- Trial name
- NCT01431651
- Testing
- probiotics,digestive enzyme
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Min-Sheng General Hospital
Obesity, Weight Gain
Endoscopic Argon Plasma Coagulation Vs. Control For Weight Regain After Gastric Surgery
Bariatric surgery procedures have consistently been demonstrated to reduce long-term co-morbidities and mortality. Despite its benefits, weight regain is common, usually initiating around two years after the initial procedure…
- Trial name
- NCT03055754
- Testing
- Argon randomized arm, Control arm
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Kaiser Clinic and Hospital
Obesity, Morbid
Clinical Outcomes of Single Stage Versus Two-stage Treatment of Severe Obesity
Laparoscopic Roux-en-Y gastric bypass (LRYGB) in super obese patients (BMI≥50kg/m2) is a challenging operation. Weight reduction with intragastric balloon (IGB) prior to LRYGB may improve operative outcomes and improves weight…
- Trial name
- NCT05146011
- Testing
- Gatsric balloon insertion
- Volunteers
- 155 people
- Sponsor
- Imperial College London
Severe Obesity
Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass
The purpose of this study is to examine the efffects of bile acid and bile acids sequestrants on GLP-1 secretion, in patients after Roux-en-Y gastric bypass.
- Trial name
- NCT02952963
- Testing
- Chenodeoxycholic Acid, Colesevelam
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Hvidovre University Hospital
Gastric Emptying, Roux-en-Y Gastric Bypass
Bariatric Procedures and Changes Gastric Passage
Gastric emptying measured with scintigraphy in patients after standard Roux-en-Y Gastric Bypass (S-RYGB), Banded-RYGB (B-RYGB) or Extended pouch-RYGB (E-RYGB).
- Conditions
- Gastric Emptying, Roux-en-Y Gastric Bypass, Bariatric Surgery
- Trial name
- BIP (NCT04972357)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Rijnstate Hospital
Severe Obesity
Comorbidity After Gastric Bypass
To evaluate effect on comorbid disease and weight loss in the long-term (>five years) after Roux-en-Y gastric bypass (RYGB) surgery for severe obesity.
- Trial name
- NCT02710786
- Testing
- Gastric bypass
- Where
- Sweden
- Volunteers
- 25,000 people
- Sponsor
- Uppsala University
Marginal Ulcer
OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers
The goal of this clinical trial is to identify the most effective way to take acid-blocking medications to treat stomach ulcers in patients who have undergone gastric bypass surgery.
- Trial name
- OPEN-IT (NCT05799105)
- Testing
- Omeprazole 40 milligrams
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Stephen Firkins
Morbid Obesity
Long-term Adverse Effects After Bariatric Surgery on Bone Density
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.
- Trial name
- FUB-A (NCT03410459)
- Testing
- DEXA (= Dual-energy x-ray absorptiometry)
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Morbid Obesity
Sleeve Gastrectomy Versus One-anastomosis Gastric Bypass: Randomized Trial
Hormonal changes after SG and OAGB involve alterations in the levels of many enteric hormones, among these hormones are ghrelin and glucagon-like peptide-1 (GLP-1).
- Trial name
- NCT04134156
- Testing
- sleeve gastrectomy, one anastomosis gastric bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University