Clinical trials: SARS CoV-2
SARS-CoV-2 (COVID-19)
Rapid Screening Circuit of COVID 19 in Schools, Pilot Study
The outbreak of coronavirus disease 2019 (COVID-19), caused by acute respiratory syndrome severe coronavirus 2 (SARS-CoV-2), emerged in Wuhan in December 2019 and has spread which poses a serious threat to public health.
- Trial name
- NCT04878809
- Testing
- Escola L'Horitzó, Escola John Talabot
- Where
- 2 sites in Spain
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Heathly Subjects Susceptible to SARS-CoV-2 Infection
Microbiome-Based Risk Prediction of SARS-CoV-2 in Children and Families (PREDICOL)
The goal of this observational cohort study is to evaluate the association between gut microbiota composition, dietary patterns, lifestyle-related factors, and neurodevelopmental outcomes, as well as susceptibility to SARS-CoV-2…
- Trial name
- PREDICOL (NCT07717008)
- Where
- Spain
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
rt PCR, COVID
SARS-CoV 2 in Personal Protective Equipment
SARS-CoV-2 transmission is frequently occurring in hospital settings, with numerous reported cases of nosocomial transmission highlighting the vulnerability of healthcare workers.
- Conditions
- rt PCR, COVID, Personal Protective Equipment PPE, SARS-CoV 2
- Trial name
- NCT04398043
- Volunteers
- 16 people
- Sponsor
- Hospital de Clinicas José de San Martín
COVID-19
Expanded Access Program of Ruxolitinib for the Emergency Treatment of Cytokine Storm From COVID-19 Infection
To provide ruxolitinib through an expanded access program for the treatment of cytokine storm due to COVID-19 in the United States to patients who are eligible but not able to be hospitalized or who are hospitalized with a…
- Trial name
- NCT04355793
- Testing
- Ruxolitinib
- Sponsor
- Incyte Corporation
Multisystem Inflammatory Syndrome in Children (MIS-C), SARS-CoV-2 Infection
Cardiovascular Assessment 5 Years After MIS-C
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication associated with SARS-CoV-2 infection that frequently affects the cardiovascular system.
- Trial name
- NCT07659847
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Coronavirus Infection
COVID-19: Epidemiological Study of the Spread of SARS-CoV-2 in the Household of a Person Who Has Had a COVID-19 Disease
Evaluating the rate of exposure to the virus in the close contact population who shared the home of a person infected with SARS-CoV-2 at the time of infection of the index case - adults or children - is a major factor in…
- Trial name
- FAMICOV (NCT04511949)
- Testing
- COVID-19 IgG / IgM rapid test (whole blood, serum, plasma)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida
SARS-CoV-2
A Study to Evaluate the Safety and Immunogenicity of the mRNA COVID-19 Vaccines in Healthy Children Between 6 Months to Less Than 6 Years of Age
This study will evaluate the safety and immunogenicity of the mRNA-1273.214 vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concerns (VOCs) in participants aged 6 months to <6 years, when…
- Trial name
- NCT05436834
- Testing
- mRNA-1273.214, mRNA-1273.815
- Where
- 74 sites in United States, Argentina and 5 more
- Volunteers
- 1,807 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Sars-CoV2, Chronic Inflammatory Rheumatism
Covid-19 in Patients With Chronic Inflammatory Rheumatism, Auto-immune or Auto-inflammatory Rare and Non-rare Diseases
Since December 2019, an international outbreak of respiratory illnesses caused by SARS-CoV-2 called covid-19 has become a global challenge.
- Conditions
- Sars-CoV2, Chronic Inflammatory Rheumatism, Autoimmune Diseases
- Trial name
- covid19 fai2r (NCT04353609)
- Where
- France
- Volunteers
- 13,770 people
- Sponsor
- University Hospital, Lille
COVID-19, COVID-19 Pandemic
Accelerating COVID-19 Clinical Recovery in the Outpatient Setting: Retrospective Analysis
The purpose of this retrospective study is to evaluate the effectiveness of CPM nasal spray as part of the treatment of COVID-19 and its impact on clinical symptoms. Two cohort groups will be compared (CPM vs. standard care).
- Conditions
- COVID-19, COVID-19 Pandemic, COVID-19 Respiratory Infection, SARS CoV 2 Infection
- Trial name
- ACCROS-R (NCT05520944)
- Testing
- ClorNovir® (Chlorpheniramine) 0.4% Nasal Spray
- Where
- Dominican Republic
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr. Ferrer BioPharma
COVID-19 SARS-CoV-2 Infection
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease.
- Trial name
- NCT06679140
- Testing
- ibuzatrelvir
- Where
- 256 sites in United States, Argentina and 17 more
- Volunteers
- 2,330 people
- Sponsor
- Pfizer
COVID-19
Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support
The COVID-19 pandemic has been spreading continuously, and in Brazil, until August 18, 2020, there have been more than 3,359,000 cases with more than 108,536 deaths, with daily increases.
- Trial name
- NCT04528368
- Testing
- Convalescent plasma
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- D'Or Institute for Research and Education
Covid-19, SARS-CoV-2
Performance of 3 Sampling Methods for the Detection of SARS-CoV-2 (COVID-19) With Real-time Reverse Transcriptase PCR
The performance of 3 different sampling methods (2 nasopharyngeal swabs, 1 oropharyngeal swab) for the detection of SARS-CoV-2 with real-time reverse transcriptase polymerase chain reaction will be compared.
- Conditions
- Covid-19, SARS-CoV-2, Diagnosis, Polymerase Chain Reaction
- Trial name
- NCT04361448
- Testing
- samling of oropharynx and nasopharynx
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Acute Kidney Injury, COVID
Pediatric Acute Kidney Injury in COVID-19
This study is an observational registry of children with or suspected to have SARS CoV2 (COVID-19) admitted to pediatric intensive care units (PICU).
- Trial name
- SPARC-1 (NCT04466306)
- Where
- 47 sites in United States, Canada and 5 more
- Volunteers
- 400 people
- Sponsor
- Children's Healthcare of Atlanta
SARS-CoV-2
Prognostic Factors of COVID19
COVID-19 is an emerging disease, for which no specific treatment options are currently available. Since the end of February 2020, and due to a SARS-CoV-2 superspreading event (religious meeting), the Strasbourg University…
- Trial name
- Covid-HUS (NCT04405726)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19 Virus Infection
Medical Herbs Inhibit Inflammation Directing T Cells to Kill the COVID-19 Virus (COVID)
The human immune system is designed to protect individuals from external sources of infection and internal cell mutation. It works effectively and efficiently until inflammation disturbs its functioning.
- Trial name
- COVID (NCT04790240)
- Testing
- Inflammation (I), Inflammation (II), Inflammation (III)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- All Natural Medicine Clinic, LLC
Covid19
the Impact of Covid-19 Pandemic Stress on Pregnancy Outcomes
This study is aiming to evaluate the effects of the COVID-19 pandemic stress on pregnancy outcomes including the sex ratio at birth.
- Trial name
- NCT04839068
- Testing
- covid 19 on pregnancy outcomes
- Where
- Egypt
- Volunteers
- 7,000 people
- Sponsor
- Assiut University
Health Behavior, Health Care Utilization
COVID-19: Healthy Oregon (Oregon Saludable): Together We Can (Juntos Podemos)
The global SARS-CoV-2 pandemic that causes the severe respiratory illness COVID-19 is the worst health crisis that the United States has faced in a century.
- Trial name
- OSJP (NCT04793464)
- Testing
- Promotores de Salud, Services as usual
- Where
- United States
- Volunteers
- 1,623 people
- Sponsor
- University of Oregon
COVID 19
Bio-reconfigurable Electronic Platform for Multiplex Detection of Viral Respiratory Pathogens
This project focuses on developing a cutting-edge electronic biosensor platform for highly sensitive and specific detection of target biomolecules, with initial applications targeting SARS-CoV-2 detection.
- Trial name
- BIOPLEX (NCT06702540)
- Testing
- Biosensor chip
- Where
- Italy
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
SARS-CoV-2 Infection, Covid19
Respiratory Aerosols in Patients With COVID-19 and Healthy Controls
The proposed study will investigate respiratory aerosols in SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) positive and negative children and adults with the Resp-Aer-Meter (Palas GmbH).
- Trial name
- NCT04739020
- Testing
- Resp-Aer-Meter, Spirometry, Qualitative and quantitative virus PCR of respiratory secretions in patients with high aerosol concentrations
- Where
- Germany
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital