Clinical trials: SNHL
Sudden Hearing Loss
Trans-round Window Membrane Intracochlear Steroid
Safety and efficacy of intracochlear injection of glucocorticoid through the round window membrane in patients with profound or complete sudden sensorineural hearing loss
- Trial name
- NCT07540728
- Testing
- Experimental: Group A: intracochlear triamcinolone acetonide injection, intracochlear injection of dexamethasone, intratympanic dexamethasone injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Sensorineural Hearing Loss
Role of Diffusion Tensor-magnetic Resonance Imaging in Investigating Sensorineural Hearing Loss
DTI and auditory tractography can be incorporated into the diagnostic toolkit for patients who are scheduled to undergo cochlear implantation and whose standard assessments have been unable to determine the functional integrity…
- Trial name
- NCT06434129
- Testing
- DTI
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University
Congenital CMV Infection
Evaluation of Long-term Efficacy of 4 to 6-month Course Antiviral Therapy for Neurodevelopmental Impairments Caused by Congenital Cytomegalovirus Infection
Title: Evaluation of Long-term Efficacy of 4-month versus 6-month Course Antiviral Therapy for Neurodevelopmental Impairment Caused by Congenital CMV Infection: A Multicenter, Randomized, Controlled, Non-inferiority Clinical…
- Trial name
- NCT07450365
- Testing
- Intravenous ganciclovir (6 mg/kg, twice daily) or oral valganciclovir (16 mg/kg, twice daily) was administered for a treatment course of 4 months., Patients received a 6-month course of anti-CMV therapy. The treatment regimen consisted of either intravenous ganciclovir (6 mg/kg, twice daily) or oral valganciclovir (16 mg/kg, twice daily).
- Volunteers
- 150 people
- Sponsor
- Hu Bofei
Neurofibromatosis Type 2, Severe Profound Sensorineural Hearing Loss
Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients
The Nucleus 24 Auditory Brainstem Implant (ABI) is the only FDA approved device for restoration of meaningful hearing in Neurofibromatosis Type 2 (NF2) patients.
- Trial name
- NCT02589912
- Testing
- Nucleus Profile ABI541 Auditory Brainstem Implant
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary
Neonatal Hearing Loss
Overview of Targeted Screening for Congenital Infection Guided by Neonatal Hearing Screening
Cytomegalovirus (CMV) infection is the most common congenital infection. It is the second leading cause of sensorineural hearing loss after genetic causes and the leading cause of motor delay.
- Trial name
- cCMV-DNS (NCT07335874)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Strasbourg, France
Sensorineural Hearing Loss, Bilateral
CI532 - Early Experience Study
To evaluate performance outcomes in patients implanted with the Cochlear Nucleus CI532 electrode array.
- Trial name
- NCT02755935
- Testing
- Cochlear Nucleus CI532
- Where
- 6 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cochlear
Sensorineural Hearing Loss
Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss
To determine if autologous human umbilical cord blood infusion in children with acquired hearing loss is safe, feasible, improves inner ear function, audition and language development.
- Trial name
- NCT02038972
- Testing
- Autologous Stem Cells
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- James Baumgartner, MD
Sensory Hearing Loss, Sensorineural Hearing Loss
The SeaSHeL National Prospective Cohort Study
Each year, approximately 15,000 people in the United Kingdom experience sudden loss of hearing that is sensorineural in nature. In the majority of cases, the cause is unknown despite investigation, and these cases are termed…
- Conditions
- Sensory Hearing Loss, Sensorineural Hearing Loss, Sensorineural Hearing Loss in Left Ear, Sensorineural Hearing Loss in Right Ear
- Trial name
- SeaSHeL (NCT04108598)
- Testing
- Quality of life questionnaire
- Where
- United Kingdom
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- University College, London
Alport Syndrome
Alport Syndrome Treatments and Outcomes Registry
ASTOR's primary purpose is to enroll families and patients with a history of Alport syndrome in a central registry. The information we gather will be used as a basis for studies designed to test potential treatments for Alport…
- Trial name
- ASTOR (NCT00481130)
- Where
- United States
- Volunteers
- 655 people
- Sponsor
- University of Minnesota
High Frequency Sensorineural Hearing Impairment, Hearing Disorders in Children
Outcomes in Children With Pre-operative Residual Hearing
Purpose: Routine clinical care and pilot study data has shown evidence of postoperative hearing preservation in pediatric cochlear implant (CI) recipients.
- Trial name
- NCT03379870
- Testing
- Electric Acoustic Speech Processor: Electric-acoustic stimulation fitting, Electric Acoustic Speech Processor: Full-electric stimulation fitting
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sensory Hearing Loss
Evaluation of N6 Sound Processor in Group of Freedom Users
Study of freedom sound processor users that upgrade to N6 sound processor CP900 series. To test speech understanding in each device and usability of upgrade.
- Trial name
- NCT02856659
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cochlear
Hearing Loss, Sensorineural Hearing Loss
Non-significant Risk Study of a Cochlear Implant Headpiece
This study aims to evaluate a cochlear implant headpiece.
- Trial name
- NCT05488535
- Testing
- cochlear implant headpiece
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Advanced Bionics
Congenital Sensorineural Hearing Loss
Analysis of Risk Factors of Neurodevelopmental Disorder in Deaf Infants Under Ten Months of Age.
Among risk factors of neurodevelopmental disorder is congenital hearing loss. However, congenital deafness is neither necessary nor sufficient for the occurrence of warning signs of neurodevelopmental disorder.
- Trial name
- EnTNDre (NCT05423548)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cochlear Implants, Sensory-Neural Hearing Loss
Balance in Children With Cochlear Implants
Cochlear implantation is performed in children with sensorineural hearing loss to restore hearing. Fifty percent of children with sensory neural hearing loss, who are candidates for cochlear implant, have vestibular (inner ear)…
- Conditions
- Cochlear Implants, Sensory-Neural Hearing Loss, Balance Disorder
- Trial name
- NCT03620500
- Testing
- Gross motor and developmental balance testing
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center