Clinical trials: Safety, Psychological
Dementia
Safety and Efficacy of Electroconvulsive Therapy (ECT) for Behavioural and Psychological Symptoms of Dementia (BPSD)
This is a prospective, open-label, observational study of the efficacy and safety of ECT for BPSD. There is no control or comparison group.
- Trial name
- ECTBPSD (NCT02969499)
- Where
- 3 sites in Canada
- Volunteers
- 33 people
- Sponsor
- University of British Columbia
Autism Spectrum Disorder, Child Safety
ESCAPE Kits for Elopement Prevention in Children With Autism
This study will evaluate elopement prevention kits for children with autism spectrum disorder who exhibit elopement behavior such as dashing or wandering away from safe settings.
- Conditions
- Autism Spectrum Disorder, Child Safety, Caregiver Stress
- Trial name
- NCT07225907
- Testing
- Elopement Prevention Kits
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Substance Use Disorders, Post-Traumatic Stress Disorder
Evaluating the Integration of Indigenous Healing With Principals of Seeking Safety for Treatment of Indigenous Patients With a History of Trauma and Active Substance Use Disorder.
Background: The negative health outcomes experienced by Indigenous peoples may be understood as direct consequences of colonization.
- Conditions
- Substance Use Disorders, Post-Traumatic Stress Disorder, Intergenerational Trauma
- Trial name
- NCT04604574
- Testing
- Indigenous Healing and Seeking Safety
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- Health Sciences North Research Institute
Medical Education, Simulation, Crisis Resource Management, Simulation Training
Using Simulation-based Team Training to Improve Psychological Safety and Relational Coordination as Well as Conducting a Process Evaluation
Simulation-based team training is increasingly used in hospitals to support teamwork and communication, particularly in situations that are complex or time-critical.
- Conditions
- Medical Education, Simulation, Crisis Resource Management, Simulation Training, Simulation Based Medical Education, Culture
- Trial name
- InfecSIM (NCT07381270)
- Testing
- Simulation-based team training
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Rare Bone Disorders
Ready to Sail 2: A Pilot Study of Sail-Assisted Telerehabilitation in Rare Skeletal Diseases
"Ready to Sail 2 - EXTEND" is a pilot randomized interventional trial designed to assess the feasibility, safety, and preliminary impact of an innovative rehabilitation model combining sailing therapy (velatherapy) with a remote…
- Trial name
- PaS2-EXTEND (NCT07102875)
- Testing
- Sailing Intervention Plus Home-Based Telerehabilitation, Home-Based Telerehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Istituto Ortopedico Rizzoli
Neonatal Care, Burnout, Professional
Developing Competency Awareness and Clinical Coordination in a Neonatal Unit
In neonatal care, patient safety depends not only on individual clinical skills, but also on how teams recognize and use the competencies available during a shift.
- Conditions
- Neonatal Care, Burnout, Professional, Psychological Safety, Interprofessional Relations
- Trial name
- NeoSim (NCT07423468)
- Testing
- Competency Awareness and Simulation-Based Intervention
- Where
- Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neurodegenerative Diseases, Osteoarthritis
Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions
To evaluate for any adverse effects that may be related to the administration and reception of autologous adipose derived stromal vascular fraction (SVF).
- Conditions
- Neurodegenerative Diseases, Osteoarthritis, Erectile Dysfunction, Autoimmune Diseases
- Trial name
- NCT01953523
- Testing
- Administration of autologous adipose derived SVF
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Elliot Lander
None - Study is to Determine Safety in Healthy Participants
Serious Game-Based School Intervention to Enhance Socio-Emotional Competence and Well-Being in European Adolescents
The goal of this study is to evaluate whether a digital, game-based social-emotional education intervention (SEL4@ll) can improve socio-emotional competencies, well-being, and inclusion in primary and secondary school students…
- Trial name
- SEL4@ll (NCT07093645)
- Testing
- SEL4@ll
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Mental Health Outcomes, Adverse Childhood Experiences
School Violence Exposure as an Adverse Childhood Experience
This study hypothesize that school safety strategies may contribute to poor mental health and distress among various school populations and proposes the following research questions to be answered through this study: 1.
- Conditions
- Mental Health Outcomes, Adverse Childhood Experiences, Perceived School Safety, Educational Outcomes
- Trial name
- NCT06153316
- Testing
- School shooting incident
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Mental Health Issue, Depressive Symptoms
Piloting +Connection is Medicine / The Healing Spirits Program
This study aims to assess what benefit, if any, an individualized coping plan and facilitating connections to care through referral coordination in conjunction with culturally tailored caring messages, (herein called the…
- Conditions
- Mental Health Issue, Depressive Symptoms, Anxiety
- Trial name
- NCT05424679
- Testing
- Safety Planning Intervention, Caring Contacts
- Where
- 4 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Development; Delayed, Mental, Anxiety
Adaptive Care in the Perioperative Setting
The overall purpose for conducting this research is to improve the safety and efficacy of care for perioperative patients who have developmental delays and behavioral challenges.
- Conditions
- Development; Delayed, Mental, Anxiety, Situational Anxiety, Fear of Other Medical Care
- Trial name
- ACT (NCT03353129)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicide, Suicide, Attempted
Suicide Prevention Among Recipients of Care
Randomized controlled trial to determine the best brief suicide prevention intervention for adults and adolescents who screen positive for suicidal ideation or behavior in emergency departments or primary care clinics.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Social Support
- Trial name
- SPARC (NCT04893447)
- Testing
- SPI+, SP+CC (Caring Contacts)
- Where
- United States
- Volunteers
- 1,520 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Erectile Dysfunction
New Treatment in Erectile Dysfunction Patients.
Erectile dysfunction patients who are non responder to sildenafil will be treated with hyperbaric oxygen therapy with 100% concentration and at 2 ATM for 30 consecutive sessions each one 90 minutes and then will be reassessed.
- Trial name
- NCT05439486
- Testing
- hyperbaric oxygen therapy within hyperbaric oxygen therapy chamber.
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Major Depressive Disorder
Phase IV:Safety and Efficacy of EMSAM in Adolescents With Major Depression
The primary purpose of your participation in this study is to help answer the following research question: Whether 12-week administration of EMSAM (selegiline transdermal system) is safe and effective for the treatment of…
- Trial name
- NCT00531947
- Testing
- Selegiline Transdermal System
- Where
- 20 sites in United States
- Volunteers
- 308 people
- Sponsor
- Somerset Pharmaceuticals
Erectile Dysfunction, Prostate Cancer
A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy
The purpose of the study is to compare the safety and effectiveness of Prograf in the prevention of erectile dysfunction in men after a radical prostatectomy.
- Trial name
- NCT00106392
- Testing
- Tacrolimus
- Where
- 6 sites in United States
- Volunteers
- 131 people
- Sponsor
- Astellas Pharma Inc
Premature Ejaculation
Safety and Efficacy of Botulinum Toxin-A Injection Into Ischiocavernosus Muscle for Premature Ejaculation
The aim of this work is to assess the efficacy and safety of Botulinum toxin - A injection into ischiocavernosus muscle in treatment of primary premature ejaculation.
- Trial name
- NCT06851598
- Testing
- 25 units botox, 50 units Botox, 75 units Botox
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Abdallah Mohamed Abdallah Mohamed Elgendy
Child Behavior Disorders
Safer Use of Antipsychotics in Youth
This study tests the effectiveness of an intervention treatment algorithm vs. usual care control in a practical clinical trial. Control arm providers will receive a standard medication alert in the electronic medical record (EMR)…
- Trial name
- SUAY (NCT03448575)
- Testing
- Control - Provider Medication Alert Only, Intervention - Alert + CAP Review AND Enhanced BH Access
- Where
- 4 sites in United States
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Bipolar Disorder, Psychotic Disorders
Determining the Safety and Effectiveness of Olanzapine in Children and Adolescents
This study will examine the safety and effectiveness of the antipsychotic drug olanzapine in children and adolescents with bipolar disorder or psychosis.
- Trial name
- NCT00183612
- Testing
- Olanzapine
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Massachusetts General Hospital
Erectile Dysfunction, Peyronie's Disease
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis
This trial will study the safety and efficacy of intravenous and intracavernosal or interstitial delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Peyronie's disease…
- Conditions
- Erectile Dysfunction, Peyronie's Disease, Interstitial Cystitis
- Trial name
- NCT05147779
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Cerebrovascular Accident
Preliminary Study of Transcranial Magnetic Stimulation for Stroke Rehabilitation
This is a preliminary study to evaluate the possible use of transcranial magnetic stimulation (TMS), together with exercise, for rehabilitation of chronic stroke patients.
- Trial name
- NCT00050128
- Testing
- rTMS, Magstim
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)