Clinical trials: Sars-CoV-2
Patient Safety
Non-COVID Patient-safety Incidents Reported by Primary Care Professionals in Time of Lockdown: Protocol for a Cross-sectional Descriptive Study
The COVID-19 epidemic is causing a global health crisis. In France, it has imposed a major reorganization of the healthcare system. This emergency reorganization is unprecedented. It involved first, second and third line care.
- Trial name
- PSI-RECORd-XP (NCT04348552)
- Testing
- Primary care professionals reports of potential patient safety incidents, non-COVID-19 related
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Covid19
Research & Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test
Evaluation of the agreement between fingerstick samples, venous blood, serum and plasma samples when using the LumiraDx SARS-CoV-2 Ab Test against the reference method, using standard qualitative comparison techniques.
- Trial name
- CAPTURE-2 (NCT04597047)
- Testing
- Capillary Collection & Testing, Venous Draw & Testing
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- LumiraDx UK Limited
SARS-CoV-2 Infection, COVID-19
Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Children
This is a Phase 1/2/3 study in healthy children. Dependent upon safety and/or immunogenicity data generated during the course of this study, and the resulting assessment of benefit-risk, the safety, tolerability, and…
- Trial name
- NCT04816643
- Testing
- Biological/Vaccine: BNT162b2 10mcg, BNT162b2 20mcg, BNT162b2 30mcg
- Where
- 128 sites in United States, Brazil and 4 more
- Volunteers
- 11,837 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
COVID
Ivermectin as a Novel Therapy in COVID-19 Treatment
Efficacy of Ivermectin in COVID-19 treatment
- Trial name
- NCT04403555
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Tanta University
Heathly Subjects Susceptible to SARS-CoV-2 Infection
Microbiome-Based Risk Prediction of SARS-CoV-2 in Children and Families (PREDICOL)
The goal of this observational cohort study is to evaluate the association between gut microbiota composition, dietary patterns, lifestyle-related factors, and neurodevelopmental outcomes, as well as susceptibility to SARS-CoV-2…
- Trial name
- PREDICOL (NCT07717008)
- Where
- Spain
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
COVID19, Coronavirus Infection
Convalescent Plasma Collection and Treatment in Pediatrics and Adults
This is a prospective study, using plasma to help fight off infections of those suffering from COVID-19 in accordance with collection guidelines for plasma and FDA IND requirements.
- Conditions
- COVID19, Coronavirus Infection, Coronavirus, Virus Diseases
- Trial name
- NCT04376034
- Testing
- Convalescent Plasma
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- West Virginia University
Fever
Timing of Surgery in Pediatric Patients Following Fever Recovery: a Prospective Cohort Study
Objectives: The timing of fever recovery may affect the risk of intra-operative hypoxemia in children undergoing elective surgery after SARS-CoV-2 infection.
- Trial name
- NCT06568809
- Testing
- Time interval between recovery of body temperature and operation
- Where
- China
- Volunteers
- 3,053 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Infection Viral
COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults (Dyn3CEA_Nosocor)
Unlike other respiratory viruses such as influenza and Respiratory Syncytial Virus (RSV) where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in…
- Trial name
- NCT04664296
- Testing
- Review of medical patient file, Phone call interview
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Hospices Civils de Lyon
COVID-19, SARS-CoV-2
Slovenian National COVID-19 Prevalence Study
The investigators are conducting a national COVID-19 prevalence survey on a sample of 3,000 inhabitants that were randomly selected from the Slovenian population.
- Trial name
- SLO-COVID-19 (NCT04376996)
- Testing
- NO intervention planned due to the observational study design - only a diagnostic testing
- Where
- Slovenia
- Volunteers
- 3,000 people
- Sponsor
- University of Ljubljana
Corona Virus Infection, SARS-CoV 2
Kidney in Coronavirus Disease 2019 Registry
The SARS-CoV-2 virus is a virus newly identified in January 2020. The WHO defined COVID-19 as a health emergency of international importance.
- Trial name
- KidneyCOVID19 (NCT04797091)
- Testing
- Retrospective data collection
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Cologne
COVID19
SARS-CoV-2 (COVID-19) Detection Using the Breath Analizer TeraSystem
The purpose of the study is to verify the sensibility and accuracy of a rapid detection test for SARS-CoV-2 in breath samples analyzed by the breath detector analyzer TeraSystem, comparing with PCR tests.
- Trial name
- NCT04497610
- Testing
- Breath sample
- Where
- Costa Rica
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Costarricense de Investigaciones Clínicas ICIC
COVID-19 Pandemic
A PhaseⅡ Study to Evaluate the Safety & Immunogenicity of SARS-CoV-2 Alpha/Beta/Delta/Omicron Variants COVID-19 Vaccine
This study is a randomized, double-blind, placebo-controlled Phase II clinical trial to evaluate the safety and immunogenicity of SCTV01E in population of different ages who have been vaccinated against COVID-19.
- Trial name
- SCTV01E (NCT05652543)
- Testing
- SCTV01E
- Where
- 4 sites in China
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Burn Out, Addiction, Smartphone
Burnout, Covid 19, Smarthphone Addiction
We investigate burnout syndrome and smartphone addiction in healthcare workers, including doctors, nurses, medical secretaries, security guards, and cleaning staff, who have been actively working from the beginning of the…
- Trial name
- NCT05248217
- Testing
- healthcare workers
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
COVID
The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment
Efficacy of Ivermectin in larger doses in COVID-19 treatment
- Trial name
- NCT04351347
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Tanta University
COVID-19
Newborns in Level III Services in Alsace From Mothers With COVID-19
Very little is known about the impact on the newborn of late pre-partum maternal SARS-CoV-2 infection. Care without separation of the mother and her newborn with continued breastfeeding has been advocated in France and by the WHO…
- Trial name
- COVID-Néo (NCT05079178)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19, Corona Virus Infection
Nasal Photodisinfection COVID-19 Proof of Concept Study
The study proposes to test photodisinfection (PDF) on SARS-CoV-2 in the nose. The study will use Health Canada approved Steriwave™ Nasal Decolonization (ND) in he nostril of patients infected with SARS-CoV-2.
- Conditions
- COVID-19, Corona Virus Infection, SARS-CoV 2
- Trial name
- NCT04615936
- Testing
- Methylene-Blue Photodisinfection
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Sunnybrook Health Sciences Centre
SARS-CoV-2, COVID-19
eVusheld Assessment reaL wORld Effectiveness at UPMC
An AstraZeneca-sponsored observational, electronic healthcare record (EHR)-embedded retrospective cohort study to assess the real-world effectiveness of EVUSHELD against SARS-CoV-2 infection, COVID-19-related hospitalization, and…
- Trial name
- VALOR-C19 UPMC (NCT05667116)
- Testing
- EVUSHELD
- Where
- United States
- Volunteers
- 4,232 people
- Sponsor
- AstraZeneca
Covid-19, SARS-CoV Infection
RT-PCR Database Analysis for COVID-19 Infections and Re-infection
The SARS-Cov2 pandemic remains associated with many concerns. One of the them is the real frequency of likely re-infection and subsequently the level of protection conferred by the acquired immunity following primary-infection.
- Trial name
- ReCOV (NCT04653844)
- Where
- France
- Volunteers
- 7,000,000 people
- Sponsor
- University Hospital, Montpellier
Incidence of CRRT With ECMO Therapy, Mortality
Outcome of ECMO and CRRT.
Background: Although acute kidney injury (AKI) is a frequent complication in patients receiving extracorporeal membrane oxygenation (ECMO), and the CRRT impact is widely studied.
- Conditions
- Incidence of CRRT With ECMO Therapy, Mortality, and Renal Recovery
- Trial name
- NCT05033509
- Testing
- supervision the Kidney fonction on ECMO
- Where
- Morocco
- Volunteers
- 30 people
- Sponsor
- Mohammed VI University Hospital
Psychological Adaptation, Psychology, Social
Psychological Impact of the Health Measures Generated by the COVID19 in Adolescents
The lockdown of the French population is a health measure put in place in response to the pandemic linked to a new coronavirus, SARS-CoV-2 (Covid-19).
- Trial name
- COVADO (NCT04406558)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil