Clinical trials: Scabies
Scabies
Efficacy and Side Effects of Blacksoap® as Adjuvant Therapy of Scabies
Background: Scabies is a skin disease due to Sarcoptes scabiei. The transmission risk is high among communities living together, such as dormitories, boarding schools, nursing homes, and so on.
- Trial name
- NCT05025696
- Testing
- Blacksoap(R)
- Where
- Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Indonesia
Scabies
Veron Scabies Education and Eradication Program
The purpose of this project is to develop a community scabies eradication and education program for the highly endemic areas surrounding the Veron community on the eastern tip of the Dominican Republic.
- Trial name
- VSEEP (NCT00604084)
- Testing
- Ivermectin, Permethrin 5% lotion
- Where
- Dominican Republic
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Scabies
Sulfur vs. Different Regimes of Permethrin for Scabies
In 2017, the World Health Organization (WHO) labeled scabies as a neglected tropical disease. It is a serious health problem especially in poor developing countries like Syria, where overcrowding, poverty, and war consequences…
- Trial name
- NCT06396507
- Testing
- Permethrin Solution, Sulfur
- Where
- 3 sites in Syria
- Volunteers
- 250 people
- Sponsor
- Damascus University
Scabies
Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies
Study to Evaluate the Therapeutic Equivalence of Permethrin Cream 5%in the Treatment of Scabies.
- Trial name
- NCT03178942
- Testing
- Permethrin Cream, 5%, Elimite™ Cream (permethrin) 5%
- Where
- 15 sites in United States, El Salvador and 1 more
- Volunteers
- 254 people
- Sponsor
- Encube Ethicals Pvt. Ltd.
Scabies
Risk Factors for Treatment Failure of Scabies in Autochthonous Populations of French Guiana (GUYAGALE)
Scabies is a Neglected Tropical Disease, particularly important in autochthonous populations. Treatment failures could explain the high prevalence of this disease in Amerindian and Maroon populations of French Guiana.
- Trial name
- GUYAGALE (NCT04931680)
- Testing
- Data collection
- Where
- French Guiana
- Volunteers
- 276 people
- Sponsor
- Centre Hospitalier de Cayenne
Scabies
Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)
The ETSKABI study is a prospective, open-label, multicenter, initially single-armed and in case of treatment failure subsequently three-armed randomized clinical trial.
- Trial name
- ETSKABI (NCT04814511)
- Testing
- InfectoScab 5 % Creme, Permethrin 10 % Creme, Driponin 3 mg Tabletten
- Where
- 8 sites in Germany
- Volunteers
- 183 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Scabies
Comparison of Permethrin and Ivermectin in Children Greater Than 6 Yrs Age for Treatment of Scabies
Scabies is highly contagious,pruritic infestation of skin.Various treatment modalities have been used but search for ideal scabicide is ongoing.we wnt to coduct this study to compare the outcome of permethrin verses ivermectin in…
- Trial name
- not existed (NCT06896929)
- Testing
- Permethrin Cream, 5%, Ivermectin 200 µg/kg
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Scabies
Ivermectin Safety in Small Children
This trial will evaluate the safety, pharmacokinetics, and efficacy of ivermectin in scabies infected children weighing 5 to less than 15kg.
- Trial name
- ISSC (NCT04332068)
- Testing
- Oral ivermectin, Permethrin Cream
- Where
- 3 sites in Brazil, Kenya and 1 more
- Volunteers
- 240 people
- Sponsor
- University of Oxford
Scabies
Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies
Globally, Scabies infects 300m people each year. In children of developing countries, its prevalence is expected to be about 5 to 10%.In Pakistan, Scabies accounts for 38% of dermatological diseases.
- Trial name
- NCT05362513
- Testing
- Ivermectin Tablets, Permethrin Cream
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Combined Military Hospital Abbottabad
Lymphatic Filariasis, Scabies
Better Options for Lymphatic Filariasis Treatment
The goal of this clinical trial is to learn if mass drug administration with moxidectin in combination with diethylcarbamazine, and albendazole (MoxDA) can treat lymphatic filariasis, scabies and strongyloidiasis in children and…
- Conditions
- Lymphatic Filariasis, Scabies, Strongyloidiasis
- Trial name
- BOLT (NCT07159373)
- Testing
- MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole
- Where
- Fiji
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Medicines Development for Global Health
Group A Streptococcal Infection, Scabies
Streptococcus Pyogenes Carriage Acquisition and Transmission Study
Group A Streptococcus (GAS) is a bacteria which causes severe infections and leads to deadly diseases such as rheumatic heart disease which kills over 300,000 people a year globally, particularly in low-income countries.
- Conditions
- Group A Streptococcal Infection, Scabies, Microbial Colonization
- Trial name
- SpyCATS (NCT05117528)
- Where
- The Gambia
- Volunteers
- 441 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Scabies
National Study on the Epidemiology and Effectiveness of Therapies in the Treatment of Scabies
Multicentre retrospective, prospective, non-profit, national observational study
- Trial name
- SCAB-net (NCT07305961)
- Testing
- data collection
- Where
- 23 sites in Italy
- Volunteers
- 1,332 people
- Sponsor
- Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse
Scabies
A Study to Evaluate the Therapeutic Equivalence of Generic Permethrin Cream 5% to Elimite® in the Treatment of Scabies
Scabies is an infestation of the skin by the human itch mite (Sarcoptes scabiei). Diagnosis of scabies is made based on clinical symptoms, such as nocturnal itching, and appearance and distribution of the rash.
- Trial name
- NCT02572986
- Testing
- Permethrin
- Where
- 13 sites in United States, El Salvador and 1 more
- Volunteers
- 250 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Scabies
Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies.
This is a multi-center, double-blind, randomized, two arm parallel design study. This study is comprised of two phases: screening and treatment.
- Trial name
- NCT02978508
- Testing
- Permethrin Cream, 5%, Elimite
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- Mayne Pharma International Pty Ltd
Scabies
Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies
To assess the safety and efficacy of Natroba (spinosad) topical suspension versus placebo for the complete cure of scabies after a single treatment.
- Trial name
- NCT02485704
- Testing
- spinosad topical suspension, 0.9%
- Where
- 7 sites in United States
- Volunteers
- 280 people
- Sponsor
- ParaPRO LLC
Malaria,Falciparum, Neglected Tropical Diseases
Adjunctive Ivermectin Mass Drug Administration for Malaria Control
This is a cluster-randomized placebo-controlled clinical trial to evaluate the additive benefit of Ivermectin (IVM) (or Placebo) mass drug administration (MDA) to dihydroartemisinin-piperaquine (DP) MDA for malaria control in a…
- Conditions
- Malaria,Falciparum, Neglected Tropical Diseases, Strongyloidiasis, Lymphatic Filariasis
- Trial name
- MATAMAL (NCT04844905)
- Testing
- Ivermectin, Dihydroartemisinin-piperaquine
- Where
- Guinea-Bissau
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Scabies, Head Lice
Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands
This is a pilot study evaluating if treatment for scabies also treats headlice in the same community
- Trial name
- NCT03236168
- Testing
- Ivermectin, Permethrin 5%
- Where
- Solomon Islands
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Streptococcus Group A
Prevalence of RHD, Pyoderma and Scabies in Children in Fiji
The purpose of this study is to estimate the number of cases of rheumatic heart disease, pyoderma, and scabies in school age children in Fiji.
- Trial name
- NCT00284843
- Where
- Fiji
- Volunteers
- 5,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Scabies
Better Disease Control by Multidrug Regimen in Scabies
Scabies is associated with significant discomfort and social taboo. Existing treatment regimen frequently fails due to lack of patient compliance.
- Trial name
- NCT05198947
- Testing
- Permethrin Lotion 5%, Permethrin Lotion 5% and Oral Ivermectin 200 mcg/kg
- Volunteers
- 212 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Lymphatic Filariases, Scabies
Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
Lymphatic Filariasis (LF), scabies and soil transmitted helminths (STH) are common neglected tropical diseases affecting the people of Fiji.
- Conditions
- Lymphatic Filariases, Scabies, Impetigo, Soil Transmitted Helminths
- Trial name
- FIT (NCT03177993)
- Testing
- 3 drug dose - IDA, 3 drug dose - IDA with second dose of ivermectin, 2 drug dose - DA
- Where
- Fiji
- Volunteers
- 4,773 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine