Clinical trials: Scar Tissue
Atrophic Scar
Role of Stem Cells, Platelet Rich Plasma in Treatment of Scars
The Objectives of this randomized controlled trial aiming to establishing a protocol of post scar revision care and to Study the effect of PRP and/or Adipose derived Mesenchymal Stem cell injection in improvement of atrophic scar…
- Trial name
- NCT03264573
- Testing
- Stem cell, MSCs
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Heba Mohamed Saad Eldien
Adhesion
Dentin Treatments for Restorations of Cervical Lesions Non-Carious
The surface of non-carious cervical lesions (LCNC) is a challenge to adhesive systems, it presents a dentin layer sclera hypermineralized, presence of bacteria and lack of mechanical retention, so this study aimed to evaluate the…
- Trial name
- NCT02434601
- Testing
- Treatment of Dentin Surface, Dentin Surface, Treatment
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Cicatrix, Hypertrophic, Burns
Laser Therapy for Pediatric Burn Scars
A new era of outcomes for pediatric burn patients has begun as burn care continues to improve. Unfortunately, complete restoration of burn-injured skin may be limited by the development of hypertrophic scarring.
- Trial name
- NCT02707627
- Testing
- Laser Therapy
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Death; Neonatal, Death, Infant
Trial to Compare BCG-Bulgaria and BCG-Denmark
The trial will be a two-year outcome assessor-blinded RCT at the maternity ward of Hospital Simão Mendes (HNSM) in urban Bissau, Guinea-Bissau to compare vaccination with Bacillus Calmette-Guérin (BCG) Danish strain (AJ Vaccines…
- Conditions
- Death; Neonatal, Death, Infant, Morbidity;Newborn, Morbidity;Infant
- Trial name
- BCGSTRAIN IV (NCT05397678)
- Testing
- BCG-Denmark, BCG-Bulgaria
- Where
- Guinea-Bissau
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cesarean Wound; Dehiscence
Removal Versus Non Removal of Ceserean Section Scar .
EXCISION of cs section skin scar and subcutaneous release versus non removal in repeated cs .aRandomized controlled trial .
- Trial name
- cs (NCT05150678)
- Testing
- removal of ceserean section scar, non removal of cesearean section scar
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assiut University
CS Scar Defect(Niche) How to Avoid
Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection
Anatomically Uterine niche is an iatrogenic pouch-like defect at the site of previous caesarean scar due to defective tissue healing.
- Trial name
- NCT06503627
- Testing
- bladder flap dissection
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Fibrosis, Scarring
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.
- Conditions
- Fibrosis, Scarring, Scar, Wounds
- Trial name
- NCT02630303
- Testing
- LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jared Jagdeo, MD, MS
Previous Cesarean Section Scar
Clinical and Ultrasound Score for Evaluation of Previous Cesarean Section Scar
Cesarean delivery rates have increased dramatically worldwide. In the United States, cesarean section (CS) rates increased from 5% of all deliveries in 1970 to a high of 31.9% in 2016.Although efforts were made to reduce the…
- Trial name
- NCT04856254
- Testing
- Trial of labor after cesarean section
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Uterine Scar Remodeling
Cesarean-scar Thickness and Closure Technique
The aim of this trial is the surgical method in cesarean deliveries, especially the uterotomy closure technique.
- Trial name
- NCT02338388
- Testing
- cesarean section technique
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Christian Bamberg
Scar
Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"
Each year, millions of burn, trauma, or surgical patients worldwide suffer from scarring that severely affects their quality of life and social functioning.
- Trial name
- NCT06437912
- Testing
- Botulinum toxin type A
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dezhou Hospital Qilu Hospital of Shandong University
Scar Keloid
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars
Summary: Keloids and hypertrophic scars are benign fibrous growth, differing mainly by overgrowth beyond the initial defect in keloid whereas hypertrophic scar is confined to initial lesion and tends to regress over the years.
- Trial name
- NCT04812626
- Testing
- 5-Fluorouracil
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
BCG Vaccination Reaction
BCG Vaccination Scar Formation in Children Under Five Years :Factors Affecting Its Formation and Subsequent Adverse Effects .
Study of BCG Vaccination scars of under five years old children . Estimation of the frequency of children without BCG scar after BCG vaccine . Evaluation of factors which may affect scar formation .
- Trial name
- bcgscars (NCT03548233)
- Testing
- bcg vaccine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cryotherapy Effect, Burn Scar
Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective…
- Conditions
- Cryotherapy Effect, Burn Scar, Scar; Previous Cesarean Section
- Trial name
- NCT05555602
- Testing
- Cold-air cooling
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lv, MD-PhD
Cicatrix, Hypertrophic
Fractional CO2 Laser Treatment of Hypertrophic Scars
Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints.
- Trial name
- NCT04236167
- Testing
- Fractional CO2 laser treatment -
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Alopecia Scar
Treatment of Alopecic Scars by Follicular Unit Extraction Hair Transplantation
This study aim: is to completely hide the alopecic scars in a way that it will not be visible.
- Trial name
- NCT06145672
- Testing
- follicular unit extraction and implantaion
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Keloid
Epidemiology Study of Keloid
Although keloid is a very common condition; there are no statistics as to its true incidence and prevalence, neither in United States, nor elsewhere in the world.
- Trial name
- NCT01423383
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tirgan, Michael H., M.D.
Atrophic Scar
The Efficacy of Combination Therapy in Atrophic Scars
There are more than 100 million patients who develop scar formation caused by various factors, such as post-inflammatory acne and trauma (1). They often have physical, aesthetic, psychological, and social barriers.
- Trial name
- NCT06298591
- Testing
- co2 laser
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cutaneous Leishmaniasis, Scar
Cosmetic Outcome of Leishmaniasis Scar After WR279396 Application
Primary Objectives: Assess whether CL (caused by Leishmaniasis major) lesions treated with WR279396 improved the cosmetic outcome compared with no treatment (natural healing)
- Trial name
- SCAR (NCT00490230)
- Testing
- WR 279396
- Where
- Tunisia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Nasal Synechiae, Adhesions of Nasal Cavity
Study of Mitomycin C and Nasal Splint to Treat Nasal Synechiae
This study evaluates whether Mitomycin C is an effective alternative to septal splints in the treatment of nasal synechiae.
- Conditions
- Nasal Synechiae, Adhesions of Nasal Cavity, Nasal Adhesions, Tissue Adhesions
- Trial name
- NCT00966056
- Testing
- Mitomycin C, Teflon nasal septal splint
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karnataka Institute of Medical Sciences