Clinical trials: Schistosoma Haematobium
Malaria Transmission
Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity
Assessing the effect of neglected tropical diseases on Plasmodium falciparum transmission in an area of co endemicity.
- Trial name
- TRANSMAL (NCT02769013)
- Testing
- Pre-treatment follow up, S. haematobium treatment, Post treatment follow up
- Where
- 2 sites in Gabon, Ghana
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Malaria
Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT)
The purpose of this study is to evaluate the clinical performance of the one-step Fyodor Urine Malaria Test (UMT), to determine its accuracy (sensitivity and specificity) for the diagnosis of Plasmodium falciparum malaria in…
- Trial name
- NCT01921413
- Testing
- Urine Malaria Test
- Where
- Nigeria
- Volunteers
- 1,893 people, healthy volunteers welcome
- Sponsor
- Fyodor Biotechnologies Inc
Schistosomiasis, Anemia
Schistosomiasis Effect on Response to Vaccines, Anaemia and Nutritional Status of Children of Northern Senegal
SchistoVAN aims to study the role of schistosomiasis infection in the modulation of the immune response of children to childhood vaccine antigens, as well as the impact of this infection on their nutritional status and their…
- Conditions
- Schistosomiasis, Anemia, Underweight, Stunting
- Trial name
- SchistoVAN (NCT01553552)
- Where
- Senegal
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Biomedical Research Center EPLS
Schistosomiasis Haematobia
Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection
Open labelled, non randomized study to evaluate the effects of Artemisinin based Combined Therapies(ACTs) on schistosomiasis since Praziquantel (PZQ) which is presently the drug of choice for treating Schistosomiasis (STS), is…
- Trial name
- SACT (NCT04264130)
- Testing
- Artesunate-Pyronaridine, Artemether-Lumefantrine, Artefenomel-Ferroquine
- Where
- Gabon
- Volunteers
- 54 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Urinary Schistosomiases
Circulating Cathodic Antigen Test Compared to Microscopy for Diagnosis of Urinary Schistosomiasis in Sohag
Schistosomiasis is a chronic infection endemic in 74 tropical and sub-tropical countries. Sub-Saharan Africa carries the highest burden (90%) of schistosomiasis which caused by both Schistosoma mansoni and Schistosoma…
- Trial name
- NCT05276414
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Schistosoma Haematobium
Performance of Tests for Schistosoma Haematobium Diagnosis
Urogenital schistosomiasis caused by infection with the blood fluke Schistosoma haematobium is a debilitating disease. The World Health Organization (WHO) has set the goal to eliminate schistosomiasis as a public health problem…
- Trial name
- SchistoBreak-D (NCT06808750)
- Testing
- S. haematobium egg detection by single urine filtration, S. haematobium egg detection by quintuple urine filtration, S. haematobium egg detection by artificial intelligence (AI) microscopy
- Where
- Tanzania
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- Stefanie Knopp
Schistosoma Hematobium Infection, Schistosomiasis Mansoni
Safety and Efficacy of Mirazid for Schistosomiasis Treatment
Clinical Trial Phase:Phase III Primary Objectives: Compare Mirazid and Praziquantel cure rates for both Schistosoma species. Compare Mirazid and Praziquantel effect in lowering the intensity of infection for both Schistosoma…
- Trial name
- PHAR0211 (NCT01529710)
- Testing
- Myrrh
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Pharco Pharmaceuticals
Hematuria, Hydronephrosis
Influence of Transmission Season on Outcome of Treatment of Schistosoma Haematobium Infection in Mozambique
To assess the influence of seasonal variations in Schistosoma haematobium transmission on treatment outcome (morbidity and re-infection)
- Trial name
- NCT00231322
- Testing
- praziquantel
- Where
- Mozambique
- Volunteers
- 520 people
- Sponsor
- DBL -Institute for Health Research and Development
Malaria, Falciparum, Hookworm Infections
Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma
The aim of this study is to investigate the change in iron metabolism in relation to malaria and helminth infections using a stable isotope technique.
- Conditions
- Malaria, Falciparum, Hookworm Infections, Schistosoma Haematobium
- Trial name
- NCT01163877
- Testing
- Fe-57 orally, Fe-58 intravenously
- Where
- Côte d’Ivoire
- Volunteers
- 43 people
- Sponsor
- Swiss Federal Institute of Technology
Diseases of the Urinary System, Schistosomiasis Haematobia
Urinary Schistosomiasis Infection
The purpose of this study is to determine what causes some people to become sick, and others not, when they are infected with the parasite Schistosoma haematobium, also known as Bilharzia.
- Trial name
- NCT00138450
- Where
- Kenya
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Urinary Schistosomiasis, Schistosoma Haematobium
Efficacy of Bilhvax in Association With Praziquantel for Prevention of Clinical Recurrences of Schistosoma Haematobium
Objectives:To reduce the risk of S. haematobium pathology recurrences during the three years following vaccine administration and to control the safety of this therapeutic strategy in children exposed to urinary schistosomiasis.
- Trial name
- Bilhvax3 (NCT00870649)
- Testing
- Bilhvax vaccine (Sh28GST)
- Where
- Senegal
- Volunteers
- 250 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Schistosomiasis Haematobia
Nanobody-based Schistosomiasis Urine Test Kit Research
This study aims to develop and evaluate a nanobody-based urine diagnostic test for Schistosoma haematobium infection through IPSE antigen detection.
- Trial name
- NCT07500740
- Testing
- Because this is an observational study, participants are not assigned an intervention as part of the study.
- Where
- Tanzania
- Volunteers
- 2,500 people
- Sponsor
- Pemba Ministry of Health Zanzibar
Schistosoma Haematobium, Schistosoma Mansoni
Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children
The SchistoSAM study is an open label, two-arm, individually-randomized controlled trial with a non-inferiority design, conducted in northern Senegal.
- Trial name
- SchistoSAM (NCT03893097)
- Testing
- Praziquantel, Artesunate + Mefloquine
- Where
- Senegal
- Volunteers
- 726 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Schistosoma Haematobium
Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis
The purpose of this study is to evaluate the efficacy of praziquantel versus As+SMP (Co-Arinate FDC ®) in the treatment of Schistosoma haematobium in 6-15 year old Malian children.
- Trial name
- NCT00510159
- Testing
- Artesunate+Sulfamethoxypyrazine/pyrimethamin, Praziquantel
- Where
- Mali
- Volunteers
- 800 people
- Sponsor
- Dafra Pharma
Urinary Schistosomiasis
Activity of Mefloquine Against Urinary Schistosomiasis
Urinary schistosomiasis is a debilitating disease in Central Africa and pregnant women are frequently suffering from this condition.
- Trial name
- NCT01132248
- Testing
- Mefloquine, S/P
- Where
- 2 sites in Gabon
- Volunteers
- 65 people
- Sponsor
- Albert Schweitzer Hospital
Schistosomiasis Hematobium, Diagnostic
Schistosomiasis Diagnosis Using a CAA Antigen Test
Schistosomiasis is one of most important human parasitic diseases worldwide. Pregnant women and their infants are two vulnerable population groups, particularly in sub-Saharan Africa, where - amongst other infectious agents …
- Conditions
- Schistosomiasis Hematobium, Diagnostic, Drug Reaction, Pregnancy
- Trial name
- FreebiLyGAB (NCT03779347)
- Testing
- Praziquantel, UCP-LF CAA, composite diagnostic
- Where
- 2 sites in Gabon
- Volunteers
- 100 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Testing, Performance
Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections.
Malaria, schistosomiasis and ancylostomiasis are three parasitic diseases which affect hundreds of millions of people and are an important cause of global mortality and morbidity.
- Conditions
- Testing, Performance, Specificity, Sensitivity
- Trial name
- INSPiRED-WP3 (NCT04505046)
- Where
- Gabon
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Schistosomiasis Haematobia
The Chinese-made Praziquantel for Treatment of Schistosoma Haematobium
Schistosomiasis remains an important parasitic disease in the tropics, special in Africa including Zanzibar. The WHO-recommended strategy to eliminate schistosomiasis involves large-scale treatment of affected populations through…
- Trial name
- NCT03133832
- Testing
- Companion Tablet
- Where
- Tanzania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jiangsu Institute of Parasitic Diseases
Sexually Transmitted Infections, Schistosoma Haematobium
Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar
A cross-sectional study of urogenital schistosomiasis and sexually transmitted infections (STI) prevalence and associated morbidity in a rural community in Madagascar.
- Trial name
- FGS/MGS/STI (NCT00713999)
- Testing
- Treatment with anti-STI and anti-schistosoma regimens
- Where
- Madagascar
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Schistosomiasis
Schistosoma Haematobium Infections and Praziquantel
The purpose of this study is to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan.
- Trial name
- NCT01558336
- Testing
- praziquantel
- Where
- Sudan
- Volunteers
- 520 people
- Sponsor
- University of Khartoum