Clinical trials: Schistosomiasis
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Schistosomiasis Haematobia
The Chinese-made Praziquantel for Treatment of Schistosoma Haematobium
Schistosomiasis remains an important parasitic disease in the tropics, special in Africa including Zanzibar. The WHO-recommended strategy to eliminate schistosomiasis involves large-scale treatment of affected populations through…
- Trial name
- NCT03133832
- Testing
- Companion Tablet
- Where
- Tanzania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jiangsu Institute of Parasitic Diseases
Schistosomiasis
Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis
Previous research undertaken among adults in high endemic districts of Busia, Adjumani, Moyo and Nebbi reported unwillingness to take preventive treatment.
- Trial name
- ESIUPT (NCT01869465)
- Testing
- Pre-treatment snack, Education arm
- Where
- Uganda
- Volunteers
- 1,277 people
- Sponsor
- Makerere University
Schistosomiasis
Women and Children as the Focus for Control of Schistosomiasis Infections in the Irrigations Area of Burkina Faso
The purpose of this study is to examine the extent of schistosomasis infections in women and children, their daily activites that encumber contact with water and their knowledge and attitudes towards the prevention of…
- Trial name
- NCT00463528
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- DBL -Institute for Health Research and Development
Schistosomiasis, Schistosomiasis Mansoni
Praziquantel in Children Under Age 4
The overall goals of this proposal are to conduct a trial to address the significant gaps with respect to our understanding of best approaches to treatment of children ages 1-4 with intestinal schistosomiasis.
- Conditions
- Schistosomiasis, Schistosomiasis Mansoni, Schistosoma Japonicum Infection
- Trial name
- PIP (NCT03640377)
- Testing
- Praziquantel
- Where
- 2 sites in Uganda, United Kingdom
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Schistosomiasis, Liver Fibrosis
Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis
Liver fibrosis is the most serious complication of schistosomiasis mansoni. However only limited proportion of subjects with infection develop this pathology and there is limited knowledge on risk factors for the differential…
- Conditions
- Schistosomiasis, Liver Fibrosis, Periportal Fibrosis, Oxidative Stress
- Trial name
- NCT01260012
- Testing
- Praziquantel+antioxidant suppl, Praziquantel+antioxidant
- Where
- Ethiopia
- Volunteers
- 414 people
- Sponsor
- Addis Ababa University
Schistosomiasis
Monitoring Schistosome Hybrids Under Under Praziquantel Pressure
The overall objective of this project is to examine and quantify the potential existence and impact on Praziquantel (PZQ) efficacy, of naturally occurring S. haematobium and S. bovis hybrid populations in northern Senegal.
- Trial name
- Sen_hybrids (NCT04635553)
- Testing
- Praziquantel 600 milligram
- Where
- Senegal
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
Schistosomiasis, Schistosoma Mansoni
Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis
The goal of this clinical trial is to learn if treating individuals living in Uganda who have liver fibrosis (scarring) due to schistosomiasis would benefit from more frequent treatment with drug praziquantel.
- Conditions
- Schistosomiasis, Schistosoma Mansoni, Liver Fibrosis, Portal Hypertension
- Trial name
- SchiFT (NCT07754617)
- Testing
- Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year
- Where
- Uganda
- Volunteers
- 600 people
- Sponsor
- Rhode Island Hospital
Schistosomiasis, Bilharzia
Arachidonic Acid Treatment Against Schistosomiasis Infection in Children
Randomized Controlled Trial: The investigational materials used in this trial were administered to subjects each day by trained clinicians.
- Trial name
- NCT02144389
- Testing
- Praziquantel (PZQ), Arachidonic acid (ARA), PZQ+ARA
- Where
- 3 sites in Egypt
- Volunteers
- 335 people
- Sponsor
- dsm-firmenich Switzerland AG
Sexually Transmitted Infections, Schistosoma Haematobium
Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar
A cross-sectional study of urogenital schistosomiasis and sexually transmitted infections (STI) prevalence and associated morbidity in a rural community in Madagascar.
- Trial name
- FGS/MGS/STI (NCT00713999)
- Testing
- Treatment with anti-STI and anti-schistosoma regimens
- Where
- Madagascar
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Schistosomiasis
Schistosoma Haematobium Infections and Praziquantel
The purpose of this study is to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan.
- Trial name
- NCT01558336
- Testing
- praziquantel
- Where
- Sudan
- Volunteers
- 520 people
- Sponsor
- University of Khartoum
Schistosomiasis
Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment
Objective and Hypotheses: This project has the overall objective of implementing and evaluating new approaches to reducing the current and future burden of urinary schistosomiasis in young children using the antihelminthic drug…
- Trial name
- NCT02495909
- Where
- Zimbabwe
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension
cardiopulmonary exercise test evaluate patients with pulmonary hypertension before and after medical or balloon pulmonary angioplasty treatment
- Conditions
- Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)
- Trial name
- CPETPH (NCT02061787)
- Testing
- balloon pulmonary angioplasty
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group