Clinical trials: Second Degree Burn
Superficial Partial Thickness Burn, Skin Graft; Complications
Nitric Oxide Generating Gel Dressing in Patients With Superficial Partial Thickness Wounds
This is a study to assess the safety and efficacy of a nitric oxide (NOx) generating dressing on superficial partial thickness (SPT) wounds. Nitric oxide has a range of effects on the body including vasodilation and angiogenesis.
- Trial name
- ProNOx2 (NCT01983085)
- Testing
- NOx dressing, Standard of Care
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Edixomed Ltd
Burn Wound, Second- or Third-degree Burn
MSCs for the Treatment of Burn Wounds
The goal of this study is to evaluate the capacity of allogenic mesenchymal stromal cells form bone marrow (BM-MSC) or adipose tissue(Ad-MSC) to induce wound healing in patients with burn wounds.
- Trial name
- NCT06103409
- Testing
- Implantation of allogeneic MSCs on burn wounds
- Where
- Venezuela
- Volunteers
- 50 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Burns, Wound Healing
A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Approximately 55-65 subjects from 3-6 sites suffering from a burn injury covering 1-25% Total Body Surface Area (TBSA) will be evaluated providing they fulfill all inclusion and none of the exclusion criteria and have given a…
- Trial name
- NCT01636362
- Testing
- Mepitel Ag
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- Molnlycke Health Care AB
Burns, Electrical Burn
The Treatment Challenges and Limitation in High-Voltage Pediatric Electrical Burn at Rural Area
A case of high-voltage pediatric electrical burn involving a fully conscious 13-year old boy who was admitted to the emergency room after being electrocuted by high-voltage power cable, with superficial partial thickness burn…
- Conditions
- Burns, Electrical Burn, Burn Degree Second, Burn Scar
- Trial name
- NCT04772573
- Where
- Indonesia
- Volunteers
- 1 people
- Sponsor
- S.K. Lerik General Hospital
Second Degree Burns
Heparin for the Treatment of Burn Wound Pain
Pain Associated with partial thickness burns (PTB) is very severe and distressing for the patients.Topical conventional treatment of superficial PTB wounds includes application of polyfax skin ointment plus lignocain gel twice a…
- Trial name
- NCT02497326
- Testing
- Polyfax & Lignocain gel or silvazine cream, Topical Heparin, Tramadol
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- King Edward Medical University
Burns
Awbat Versus Biobrane in Partial Thickness Burns
To determine if AWBAT, used in treating partial-thickness burns, would provide better healing, pain control, control of infection, shorter length of hospital stay, lower costs, and improved scarring and long term recovery when…
- Trial name
- Awbat (NCT00847496)
- Testing
- AWBAT, Biobrane
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns Degree Second, Pediatric
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO).
- Trial name
- CHITAG (NCT06987981)
- Testing
- Chitosan-based dressing, Silver-based dressing
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Miloš Potkonjak
Burns Degree Second
Use of Platelet-rich Plasma in Second-degree Superficial Burns
Platelet-rich plasma (PRP) obtained from the patient's blood has been used in many clinical and experimental studies, primarily wound healing, and successful results have been achieved.
- Trial name
- NCT04276818
- Testing
- PRP group, conventional treatment group
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Second-degree Burn
Mepilex Ag vs. Xeroform in Pediatric Patients That Sustain Partial Thickness Burn Injury
Pediatric patients that sustain partial thickness burn injuries to their extremities require regular scheduled dressings and weekly appointments for better healing.
- Trial name
- NCT04149808
- Testing
- Mepilex Ag (burn dressing), Xeroform Dressing
- Where
- United States
- Sponsor
- Wayne State University
Burn, Partial Thickness
Using Santyl or Bacitracin on Second Degree Burns
Subjects who have minor, second degree burns may be enrolled in this study. Subjects will receive either Santyl ointment or bacitracin ointment to apply to the burn until it heals.
- Trial name
- NCT01516463
- Testing
- Collagenase Santyl, Bacitracin
- Sponsor
- Healthpoint
Deep Partial Thickness Burn
Efficacy and Safety Study of rhGM-CSF Gel to Treat Deep 2nd Thickness Burn
This was a multicenter, randomized, phase Ⅳ study, to investigate the extensive efficacy and safety of Recombinant Human Granulocyte/Macrophage Colony-stimulating Factor Hydro-gel for Topical Application (rhGM-CSF Gel) on deep…
- Trial name
- rhGM-CSF (NCT01785784)
- Testing
- rhGM-CSF Gel
- Volunteers
- 2,510 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Burns
Virtual Reality on Pain and Range of Motion on Burn
The Purpose of the study is to determine the effect of virtual reality exercise on pain and shoulder range of motion in pediatrics with 2nd-degree anterior shoulder burn injuries.
- Trial name
- NCT05352711
- Testing
- active assisted exercise and with fully immersive Head-Mounted Display virtual reality ( Oculus Quest virtual reality (VR) headset with hand con, active assisted range of motion exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Burns
ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
This is a randomized, within-subject controlled study to compare the clinical performance of the ReCell device when used as an adjunct to meshed skin graft in subjects requiring skin grafts for closure of burn injuries.
- Trial name
- NCT02380612
- Testing
- ReCell Treatment, Skin Graft
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Avita Medical
Burn Wounds - Partial Thickness (2nd Degree)
Bacterial Control in Partial Thickness Burns Using Silver-containing Wound Dressings
This study is to compare the treatment with two different silver-containing wound dressings: aquacel AG hydrofiber versus acticoat burn dressing.
- Trial name
- NCT00343824
- Testing
- aquacel AG hydrofiber versus acticoat burn dressing
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Partial-thickness Burn
Performance and Safety of Exufiber Ag+ and Exufiber on Partial Thickness Burns
This a multi-center, open label, non-comparative, study that will evaluate the clinical safety and performance of Exufiber Ag+ and Exufiber dressings, separately, when used as intended in moderate to high exuding partial…
- Trial name
- NCT04839523
- Testing
- Exufiber, Exufiber Ag+
- Where
- 6 sites in United States
- Volunteers
- 44 people
- Sponsor
- Molnlycke Health Care AB
Burn Injuries
Mepilex Ag Versus Silver Sulfadiazine in Children and Adults With Burn Injuries.
The purpose is to compare time to healing using absorbent foam silver dressing (Mepilex Ag) compared to a silver sulfadiazine (SSD) 1% cream in the treatment of partial thickness burn injuries.284 in-patients in 8-12 centres in…
- Trial name
- NCT01439074
- Testing
- Mepilex Ag, Silver Sulphadiazine Ag cream
- Where
- 9 sites in China
- Volunteers
- 162 people
- Sponsor
- Molnlycke Health Care AB
Partial-Thickness Burn, Thermal Burn
Silver Sulfadiazine With Hyaluronic Acid Versus Silver Sulfadiazine Alone in Partial-Thickness Burns
Partial-thickness burns are commonly treated with topical silver sulfadiazine; however, its use may delay epithelialization due to cytotoxic effects on regenerating cells.
- Trial name
- NCT07367087
- Testing
- Silver Sulfadiazine With Hyaluronic Acid, Silver Sulfadiazine
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dr Muhammad Naveed Shahzad
Partial-thickness Burn
PermeaDerm® vs. Mepilex-Ag® in Promoting Healing of Partial-thickness Burn Wounds
The purpose of this study is to compare the effectiveness of the wound dressings currently used at our institution for partial-thickness burn wounds: PermeaDerm® (PermeaDerm, Inc., Carlsbad, California, USA) and silver…
- Trial name
- NCT03613870
- Testing
- PermeaDerm, Mepilex Ag
- Sponsor
- The University of Texas Medical Branch, Galveston
Skin Burn Degree Second
Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.
- Trial name
- NCT01790763
- Testing
- Keramatrix, Mepilex
- Where
- United States
- Sponsor
- The University of Texas Medical Branch, Galveston
Superficial and Superficial Partial Thickness Burns
Effectiveness of Alovera Gel vs 1% Silver Sulfadiazine in Superficial Partial Thickness Burn Patients in Pediatric Population.
This prospective randomized controlled study aims to compare the effectiveness of Aloe vera gel versus 1% silver sulfadiazine in the treatment of superficial and superficial partial-thickness burns in the pediatric population.
- Trial name
- NCT07716605
- Testing
- Silver sulfadiazine 1%cream, Alovera gel
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore