Clinical trials: Second Trimester Abortion
Induced Abortion
Comparison of Two Regimens of Misoprostol for Second Trimester Medical Termination of Pregnancy
The hypothesis of the study is that the induction abortion interval time will be significantly shorter in the group receiving vaginal misoprostol every six hours in comparison to the group who are receiving vaginal misoprostol…
- Trial name
- NCT00401440
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 185 people
- Sponsor
- Nilratan Sircar Medical College
Placenta, Retained, Postpartum Hemorrhage
Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption
Interruption of a pregnancy after 14 weeks gestation may be required when the fetus is dead, severely malformed or in cases of maternal illness.
- Trial name
- NCT00120042
- Testing
- Misoprostol, Oxytocin
- Where
- Australia
- Volunteers
- 251 people
- Sponsor
- The University of Western Australia
Labor Induction
Factors Influencing the Abortion Interval of Second-trimester Termination of Pregnancy Using Misoprostol
This study aims to analyze the factors influencing the abortion interval of second-trimester termination of pregnancy using misoprostol.
- Trial name
- NCT01927822
- Where
- Taiwan
- Volunteers
- 101 people
- Sponsor
- Far Eastern Memorial Hospital
Induced Abortion, Second Trimester Abortion
Midlevel Versus Physician-provided Medical Abortion in the Second Trimester
The purpose of the study is to determine the safety and effectiveness of second trimester medical abortion when provided by nurse midwives compared with physicians.
- Conditions
- Induced Abortion, Second Trimester Abortion, Medical Abortion, Health Personnel
- Trial name
- NCT04181541
- Testing
- Provider type: Physicians, Provider type: Midlevel Providers
- Where
- Ethiopia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Ipas
Pregnancy
Better Contraceptive Choices: Immediate or Delayed Insertion of IUC After Second Trimester Abortion
Hypothesis Intrauterine contraception placed immediately after a second trimester abortion will result in fewer pregnancies than current standard practice of intended placement at 4 weeks post-abortion.
- Trial name
- NCT00877344
- Testing
- Immediate insertion, Interval insertion
- Where
- 3 sites in Canada
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Incomplete Abortion
Misoprostol Treatment of Mid Trimester Incomplete Abortion by Midwives and Doctors in Uganda.
It is estimated that 47,000 women die every year due to consequences of unsafe abortion globally. The majority of pregnancy related deaths occur in low income countries where induced abortion is restricted, unmet need for…
- Trial name
- NCT03622073
- Testing
- Misoprostol treatment by Midwife, Misoprostol treatment by Doctor
- Where
- 14 sites in Uganda
- Volunteers
- 1,191 people
- Sponsor
- Makerere University
Second Trimester Abortion
Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion
the investigators aimed to study the efficacy and safety of nitric oxide donors when combined with prostaglandins in induction of second trimester abortion expecting that both drugs when used together will be of greater…
- Trial name
- NCT03407521
- Testing
- Misoprostol, isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
Analgesia for 2nd Trimester Termination of Pregnancy
There has been very little investigation into the management of pain from 2nd trimester termination of pregnancy or unexpected fetal loss.
- Trial name
- NCT01563835
- Testing
- bupivacaine, fentanyl, fentanyl
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Abortion, Induced, Labor Stage, Third/Drug Effects
Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention.
- Conditions
- Abortion, Induced, Labor Stage, Third/Drug Effects, Pregnancy Trimester, Second, Oxytocin/Administration & Dosage
- Trial name
- NCT02485444
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ataturk University
Abortion, Induced
Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions.
- Trial name
- NCT00383032
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Abortion in Second Trimester
Outpatient Service for Mid-trimester Termination of Pregnancy
This study seeks to evaluate the safety, acceptability and feasibility of an outpatient "day procedure" for medical abortion at 13-18 weeks gestation.
- Trial name
- NCT03346629
- Testing
- Mifepristone + Misoprostol
- Where
- 3 sites in Nepal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Second Trimester, Procedural Pain
Cervical Preparation for Same-Day Dilation & Evacuation
This is a noninferiority randomized control trial of two cervical preparation methods prior to same-day Dilation \& Evacuation (D\&E). Cervical preparation is a process that softens and dilates the cervix prior to a procedure.
- Conditions
- Abortion, Second Trimester, Procedural Pain, Procedural Complication
- Trial name
- NCT06799052
- Testing
- Transcervical single-balloon catheter, Synthetic osmotic dilators
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14 - 21 Weeks LMP): A Randomized-controlled Double-blinded Trial
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00784186
- Testing
- mifepristone+misoprostol, misoprostol
- Where
- 2 sites in Vietnam
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Miscarriage
Could Colour Dopper Improve the Diagnosis of Retained Placental Fragments After Second Trimester Miscarriage ?
Value of pelvi- abdominal ultrasound and Doppler in diagnosis of retained products of conception after second trimester miscarriage to select who will benefit from surgical evacuations or conservative management.
- Trial name
- NCT02419300
- Testing
- ultrasoungraphy
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Ain Shams University
Abortion in Second Trimester
Mifepristone and Misoprostol for Midtrimester Termination of Pregnancy in Uzbekistan
The primary goal is to examine the efficacy and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Uzbekistan.
- Trial name
- NCT02235155
- Where
- 3 sites in Uzbekistan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects