Clinical trials: Sedation Strategies
Intellectual Disability, Perceptual Disorders
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
The purpose of this study is to determine the relationships between sedative exposure during pediatric critical illness and long-term neurocognitive outcomes.
- Conditions
- Intellectual Disability, Perceptual Disorders, Memory Disorders
- Trial name
- RESTORE-cog (NCT02225041)
- Where
- 31 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Intensive Care Unit, Postoperative Care
Pharmacokinetics-pharmacodynamics and Safety of Dexmedetomidine in Children
This study evaluates pharmacokinetics and pharmacodynamics of dexmedetomidine for children under sedation at intensive care unit after surgery.
- Trial name
- NCT04027829
- Testing
- Dexmedetomidine Hydrochloride
- Where
- South Korea
- Volunteers
- 13 people
- Sponsor
- Seoul National University Hospital
Daily Sedative Interruption, Sedation Strategies
Pilot Study for Sedation Interruption in Children
The purpose of this study is to estimate the hypothesized benefit of sedation interruption protocol on mechanical ventilation duration and PICU length of stay.
- Conditions
- Daily Sedative Interruption, Sedation Strategies, Sedation Protocols, Mechanical Ventilation
- Trial name
- NCT02426320
- Testing
- Sedation Interruption Protocol, Standard Sedation Protocol
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Davinia Withington
Critical Illness
Development and Evaluation of Strategies to Improve Sedation Quality in InTensive Care
Intensive Care Units (ICUs) across Scotland are working with the Scottish Patient Safety Programme (SPSP) to reduce healthcare associated infections (HAls). This is being done through implementation of "care bundles".
- Trial name
- DESIST (NCT01634451)
- Testing
- Bespoke on-line sedation education package, Sedation specific outcome process feedback, Responsiveness monitoring; novel sedation monitor
- Where
- United Kingdom
- Volunteers
- 1,637 people
- Sponsor
- University of Edinburgh