Clinical trials: Sedation and Analgesia
Moderate, Deep Sedation
Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children
There is a wide variation of published IV ketamine dosing regimens used for procedural sedation in children in the Emergency Department (ED).
- Trial name
- NCT02519595
- Testing
- Ketamine IV 1mg/kg, Ketamine IV 1.5mg/kg, Ketamine IV 2mg/kg
- Volunteers
- 182 people
- Sponsor
- Children's Hospital of Michigan
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
In the United States, the majority of first-trimester surgical abortions are performed in outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain control.
- Trial name
- NCT01011634
- Testing
- Intravenous moderate sedation versus oral medication
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Procedural Sedation and Analgesia
Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department
The purpose of this study is to compare the effectiveness of the co-administration of intravenous ketamine and propofol to intravenous ketamine as a single agent for procedural sedation in the pediatric emergency department.
- Trial name
- NCT01387139
- Testing
- Ketamine, Ketamine Co-administered with Propofol
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of Colorado, Denver
Conscious Sedation
Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies
The role of Adjunct therapies such as Child Life therapy and Music listening during Procedural Sedation and Analgesia(PSA) for children during painful procedures has not been studied in the Emergency Department (ED).
- Trial name
- NCT02518919
- Testing
- Child life intervention, Music listening
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's Hospital of Michigan
Laceration of Skin
IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair
Often, repair of the cuts (laceration repair) proves to be traumatic for the children and the parents. Nasal spray (Intranasal/IN) approaches for procedural pain reduction, such as during dental work, have been demonstrated to…
- Trial name
- NCT03528512
- Testing
- Ketamine, Midazolam and fentanyl
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Corewell Health East
Agitation
Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit
The purpose of this study is to determine whether acupuncture is effective at improving comfort in children on a ventilator in the intensive care unit.
- Trial name
- NCT01848158
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Seattle Children's Hospital
Otitis
Dexmedetomidine vs Fentanyl for BMT
A randomized controlled clinical trial to examine effects of intranasal dexmedetomidine, an α2-adrenorecptor agonist, on pain control and agitation in children undergoing BMT.
- Trial name
- DexBMT (NCT00654329)
- Testing
- Saline, Fentanyl, Dexmedetomidine
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Procedural Sedation and Analgesia
Combined Ketamine/Propofol for Emergency Department Procedural Sedation
Introduction Numerous drugs and combinations of drugs are used for procedural sedation and analgesia (PSA) in Emergency Departments, including propofol, ketamine, benzodiazepines, narcotics, barbiturates, and others, but propofol…
- Trial name
- NCT01126957
- Testing
- Ketamine, Fentanyl, Propofol
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia