Clinical trials: Seizures Disorders
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- NCT05096273
- Testing
- ReACT
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bronchiolitis, Gastroenteritis
Viral Respiratory and Gastrointestinal Infections in Children Under 6 Years of Age
With the use of molecular methods new viruses have been detected in respiratory and gastrointestinal tracts of both patients and asymptomatic subjects in recent years.
- Conditions
- Bronchiolitis, Gastroenteritis, Convulsion, Febrile
- Trial name
- NCT00987519
- Where
- 3 sites in Slovenia
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Plagiocephaly, Nonsynostotic
Observe the Effects of the Serkel Cranial Remolding Orthosis on Infants With Deformational Plagiocephaly
The purpose of this study is to determine the safety and effectiveness of a specific brand of cranial remolding orthosis (a custom made helmet), which is new to the United States market
- Trial name
- NCT06831513
- Testing
- Serkel 3D CRO
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Epilepsy
Ketogenic Diet Program for Epilepsy
This study will assess the effectiveness of the ketogenic diet (high-fat, low-carbohydrate, and moderate protein) in treating epilepsy.
- Trial name
- NCT02497105
- Testing
- Ketogenic Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Seizures Newborn, Brain Injuries
Newborn Brain Test (NBT)
The aim of the overall project is to develop the Newborn Brain Test (NBT), a novel platform to detect abnormal brain activity in infants at birth through an automated AI assessment.
- Trial name
- NBT (NCT06580834)
- Testing
- Cergenx Wave
- Where
- Ireland
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Professor Geraldine Boylan
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT) R33 Phase
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- ReACT (NCT06007053)
- Testing
- ReACT, Supportive Therapy
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Epilepsy, Status Epilepticus
Creation, Implementation, and Analysis of a Seizure Action Plan
Data strongly suggests that aggressive and early treatment of status epilepticus (SE) is crucial for seizure abortion and prevention of long-term neurologic sequelae.
- Trial name
- NCT02995759
- Testing
- Seizure Action Plan
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Childhood Absence Epilepsy, Petit Mal Epilepsy
Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study
The purpose of this study is to determine the best initial treatment for childhood absence epilepsy.
- Conditions
- Childhood Absence Epilepsy, Petit Mal Epilepsy, Epilepsy, Seizures
- Trial name
- NCT00088452
- Testing
- Ethosuximide, Lamotrigine, Valproic acid
- Where
- 31 sites in United States
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Epilepsy, Seizures
A Study of the Effectiveness of Risk Minimization Measures Related to Depakine® (Sodium Valproate) in Saudi Arabia
A cross-sectional, national, multicenter, survey-based study to assess the effectiveness of Risk Minimization Measures related to Depakine® (sodium valproate) in Saudi Arabia.
- Trial name
- DEPAKINE PASS (NCT06714448)
- Testing
- Sodium valporate
- Where
- France
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Sanofi
Childhood Absence Epilepsy, Absence Seizures
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
This study wants to make it easier to find kids with a type of epilepsy called childhood absence epilepsy (CAE) who might have problems with ongoing seizures and thinking.
- Conditions
- Childhood Absence Epilepsy, Absence Seizures, Epilepsy Comorbidities
- Trial name
- ACER (NCT06310772)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eysz, Inc.
SUDEP
Risk Factors for Sudden Unexplained Death in Epilepsy
The main purpose of this study is to develop a North American registry for SUDEP cases; requesting family members of epilepsy patients who died suddenly of unclear causes (SUDEP) to contact the study team.
- Trial name
- SUDEP (NCT01662453)
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Childhood Absence Epilepsy
Why Are Patients With Absence Seizures Absent? A Brain Imaging Study
Our study examines which different brain regions are involved in child absence seizures and how they are related to attention and cognition.
- Trial name
- NCT00393666
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Virtual Reality, Epilepsy
Effect of VR-ESMEPP on Parents' Seizure Management
Objective: This study aims to evaluate the knowledge, skills, and motivation of parents regarding management of epileptic seizures, by developing a "Virtual Reality Based Seizure Management Education Program for Parents…
- Conditions
- Virtual Reality, Epilepsy, Seizure, Child
- Trial name
- VR-ESMEPP (NCT05500638)
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Epilepsy
Herpes Virus-6 and Epilepsy
This study will explore whether the human herpes virus-6 is associated with epileptic seizures. The virus may be involved in brain scarring, called mesial temporal sclerosis, which is seen in some epilepsy patients.
- Trial name
- NCT00085683
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dehydration, Seizure
Point of Care Device Use in the Pediatric Emergency Department
To compare the effect of "point-of-care" (POC) analysis of blood work with traditional laboratory methods on length of stay in a pediatric emergency department (PED).
- Conditions
- Dehydration, Seizure, Gastroenteritis, Hyperglycemia
- Trial name
- NCT00285285
- Testing
- Point of Care Device; i-Stat Analyzer
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Febrile Seizure
A Cross-Sectional Study of Serum Levels of Adipocytokines in Children With Febrile Seizures
Febrile seizure (FS) is a common neurological condition in children, affecting 2 - 14% of children. FS is defined as seizures occurring in a child aged from six months to five years that is accompanied by a fever (≥38°C) without…
- Trial name
- NCT04967066
- Testing
- Serum Levels of Adipocytokines
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Healthy
Effect of Talampanel (an AMPA Receptor Blocker) on Brain Activity
This study will use transcranial magnetic stimulation (TMS) and electroencephalography (EEG) to test the safety of an experimental anti-epileptic drug called Talampanel and learn how it affects brain activity.
- Trial name
- NCT00057460
- Testing
- Talampanel
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Seizures
Seizure Identification on the Intensive Care Unit (ICU)
The aim of this project is to assess the ability of different groups of National Heath Service (NHS) professionals to correctly identify clinical seizures, and distinguish them from other movements commonly seen in the ICU…
- Trial name
- NCT07136298
- Testing
- Clinical Opinion
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Face, Newborn
Fitting of Commonly Available Face Masks for Late Preterm and Term Infants
Around ten percent of newborn infants require positive pressure ventilation (PPV) in the delivery room. This is most commonly delivered using a round or anatomically shaped face mask attached to a T-piece device, self-inflating…
- Conditions
- Face, Newborn, Preterm Infant
- Trial name
- CAFF (NCT03369028)
- Testing
- 2D and 3D image of infants´ faces
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen