Clinical trials: Self-harm Behavior
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Sleep Problems, Suicidal Ideation
Sleep Treatment for Teens (RCT Phase)
The purpose of this research study is to compare (vs. treatment as usual) a brief (6-session), empirically supported, and highly disseminable version of digital (i.e., smartphone or web-based) cognitive behavioral therapy for…
- Conditions
- Sleep Problems, Suicidal Ideation, Suicidal Behavior
- Trial name
- NCT07303959
- Testing
- Sleepio, Treatment as Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Problem Behavior, Aggression
Manualized Assessment and Treatment Model of Challenging Behavior
Despite decades of mounting single-case-design evidence for the efficacy of applied behavior analysis (ABA) and other approaches for the assessment and treatment of challenging behavior, an evidence-based comprehensive approach…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05928247
- Testing
- Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Suicide Prevention, Communication
Chatsafe Netherlands: Improving Safe Suicide Communication for Young People on Social Media
Suicide is the leading cause of death among young people (YP) aged 10 to 25 years in the Netherlands. In addition, YP report high rates of suicidal ideation (16%).
- Conditions
- Suicide Prevention, Communication, Social Media
- Trial name
- CSNL (NCT06364332)
- Testing
- Social Media campaign
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 113 Suicide Prevention
Suicide, Attempted
Evaluation of a Regional Post-discharge Monitoring System for Suicide Attempters
VigilanS is an innovative healthcare program. Participants of this program are all patients leaving in the Nord-Pas de Calais region who survived a suicide attempt.
- Trial name
- EVAL-VIGILANS (NCT03134885)
- Where
- 28 sites in France
- Volunteers
- 12,989 people
- Sponsor
- University Hospital, Lille
Suicide Ideation, Suicide Attempt
Plan and Protect: Safety Planning for Teens in Rural Emergency Departments
The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \& Protect (P\&P) within rural emergency departments can improve home safety and…
- Trial name
- NCT07325474
- Testing
- Plan & Protect safety planning intervention, Care as usual
- Where
- 6 sites in United States
- Volunteers
- 550 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Obsessions, Suicide
Obsessions and Suicidality in Youth With Bipolar 1 Disorder
Obsessive-compulsive disorder (OCD) is a common co-morbidity with bipolar I disorder, a comorbidity that is known to increase suicide risk.
- Conditions
- Obsessions, Suicide, Bipolar I Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05878808
- Testing
- Psychometric assessment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Self-Injurious Behavior, Mental Retardation
Self-Injury: Diagnosis and Treatment
Self-injurious behavior is behavior in which a person hurts or harms himself. This behavior sometimes occurs in people with mental retardation or autism.
- Trial name
- NCT00065936
- Testing
- Naltrexone hydrochloride, Transcutaneous sensory nerve stimulation
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Suicide, Self Harm
An Adaptive Intervention for Adolescents at Risk for Suicide: A Pilot SMART
To inform the development of a technology-augmented adaptive intervention for adolescents at risk for suicide, the goal of this study is to conduct a Sequential, Multiple Assignment, Randomized Trial (SMART) pilot of a…
- Trial name
- NCT03838198
- Testing
- MI-Enhanced Safety Plan at Hospitalization (1st Component), MI-Enhanced Text Boosters (2nd Component), MI-Enhanced Booster Call (3rd Component)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol for Chinese Adolescents With Non-Suicidal Self-Injury: A Randomized Controlled Trial
This study is an open-label, randomized controlled trial evaluating the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) in reducing non-suicidal self-injury (NSSI) among…
- Trial name
- NCT07110181
- Testing
- a blended version of the Unified Protocol for Adolescents (UP-A), Standard psychiatric treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jian-Jun Ou
Major Depressive Disorder (MDD), Suicidal Ideation
Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation
Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).
- Conditions
- Major Depressive Disorder (MDD), Suicidal Ideation, Hospitalization in Children
- Trial name
- IMPACT-D (NCT07217444)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Suicide, Mental Health Disorder
A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- NCT05920252
- Testing
- Vira, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Ksana Health
Depression
EEG-Triggered rTMS and Group Therapy for Adolescents With Depression and Self-Harm
This randomized controlled trial aims to evaluate the efficacy of real-time EEG-triggered repetitive transcranial magnetic stimulation (rTMS) combined with group therapy versus rTMS alone in adolescents (aged 12-18 years)…
- Trial name
- NCT07047534
- Testing
- Real-time EEG-triggered Repetitive Transcranial Magnetic Stimulation (rTMS), Group Therapy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Hospital of Hebei Medical University
Nightmare, Suicidal Ideation
Cognitive-Behavioral Therapy for Children With Nightmares
The goal of this clinical trial is to assess the efficacy of CBT-NC intervention to determine its impact on mental health and suicidality in children ages 6-17.
- Conditions
- Nightmare, Suicidal Ideation, Children, Only
- Trial name
- NCT06033781
- Testing
- Cognitive Behavioral Therapy for Nightmares in Children
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of Oklahoma
Suicidal Ideation, Suicide Attempt
The Epidemiology of Suicide Attempts and Suicidal Thoughts in Flanders
The objective of this study is to collect data in Flanders on the incidence of suicide attempts and suicidal ideation across various healthcare settings.
- Conditions
- Suicidal Ideation, Suicide Attempt, Multicenter Study, Epidemiological Study
- Trial name
- BC-03869 (NCT07021404)
- Testing
- Semi-structured interview (Guideline for Suicide care and Evaluation =LOES)
- Where
- 33 sites in Belgium
- Volunteers
- 50,000 people
- Sponsor
- University Hospital, Ghent
Lesch-Nyhan Disease
Safety and Tolerability of the D1 Dopamine Receptor Antagonist Ecopipam in Patients With Lesch-Nyhan Disease
The purpose of this study is to determine the effects of ecopipam in patients with Lesch-Nyhan Disease (LND). Ecopipam specifically blocks the actions of one chemical in the brain that helps nerves talk to one another; ecopipam…
- Trial name
- NCT01065558
- Testing
- Ecopipam
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Psyadon Pharma
Suicide
Prevention of Recurrence of Suicide Attempt by Adolescent by Sending SMS (MEDIACONNEX)
MEDIACONNEX study propose a new way of connectedness for adolescents after a suicide attempt: it is based on the sending of SMS (or mail or other new media), over a period of 6 months after their suicide attempt (SA), in order to…
- Trial name
- MEDIACONNEX (NCT02762734)
- Testing
- MEDIA
- Where
- 5 sites in France
- Volunteers
- 225 people
- Sponsor
- Central Hospital, Nancy, France
Suicide, Major Depressive Disorder
Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients
This study will try to provide a better understanding of the psychological, cognitive and electrophysiological factors that contribute to suicide in depressed patients.
- Conditions
- Suicide, Major Depressive Disorder, Quantitative EEG (qEEG)
- Trial name
- NCT04104698
- Testing
- Quantitative EEG
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Suicidal Ideation and Behavior
Stepped-Care for Suicidal Youth and Children
The goal of this RCT study is to test the efficacy of a stratified stepped-care (SSC) model in reducing suicidal thoughts and behaviors (STB) in children and adolescents. The main questions it aims to answer are: 1.
- Trial name
- SURE-CARE (NCT07321171)
- Testing
- IPC-A-SCI (Interpersonal Counseling for Suicide Crisis Intervention), IPT-A-SCI (Interpersonal Psychotherapy for Adolescents with Suicidal Crisis Intervention)
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Shira Barzilay