Clinical trials: Separation Anxiety
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence
Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD
Anxiety disorders in children and adolescents are common and confer significant disability. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost…
- Conditions
- Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD)
- Trial name
- ASTRO (NCT07024758)
- Testing
- Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety Disorder, Social Phobia
Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety disorders in community health centers.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
- Trial name
- NCT01416805
- Testing
- Computerized Cognitive Behavioral Therapy, Treatment as usual
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Generalized Anxiety Disorder (GAD), Anxiety, Separation
SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
This study will evaluate the safety and tolerability of SPD503 in subjects aged 6-17 years with GAD, SAD, or SoP based on treatment emergent adverse events (TEAEs), vital signs and ECGs.
- Conditions
- Generalized Anxiety Disorder (GAD), Anxiety, Separation, Phobia, Social
- Trial name
- NCT01470469
- Testing
- SPD503 (extended-release Guanfacine hydrochloride)
- Where
- 33 sites in United States
- Volunteers
- 83 people
- Sponsor
- Shire
Anxiety Disorders, Separation Anxiety Disorder
A Research Study of How Teens With and Without an Anxiety Disorder Make Decisions
The purpose of this trial is to study how teens with and without an anxiety disorder make decisions. This is a brain imaging study using functional magnetic resonance imaging (fMRI) in adolescents between the ages of 13 and 17.
- Conditions
- Anxiety Disorders, Separation Anxiety Disorder, Phobic Disorders
- Trial name
- NCT00104195
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions…
- Conditions
- Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety
- Trial name
- NCT04922502
- Testing
- Standard SPACE, Bibliotherapy, low therapist contact SPACE
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Separation Anxiety Disorder, Generalized Anxiety Disorder
Acoustic Neuromodulation (ANM) for Youth With Anxiety Disorders
The acoustic neuromodulation trial (ANM-T) is a two-phase, single-site, pilot randomized clinical trial examining the feasibility of completing a larger scale efficacy study of a novel treatment of non-linear modulated acoustic…
- Conditions
- Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia
- Trial name
- ANM (NCT02572973)
- Testing
- Acoustic Neuromodulation (ANM)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Separation, Family, Separation Anxiety
Use Of Midazolam In Premedication Of Pediatric Patients
: The aim of the study is to compare the effect of intranasal and oral midazolam administered for premedication to children of preschool age on hemodynamic parameters, sedation and separation from parents.
- Trial name
- NCT07021755
- Testing
- midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Anxiety Disorders, Anxiety, Separation
Explanatory Clinical Trial of a Novel Parent Intervention for Childhood Anxiety (SPACE)
Childhood anxiety disorders are very common, carry tremendous personal and societal costs, frequently do not respond adequately to treatment, and involving parents in treatment has so far not enhanced outcomes.
- Conditions
- Anxiety Disorders, Anxiety, Separation, Phobic Disorders
- Trial name
- SPACE (NCT02310152)
- Testing
- Parent-Based Treatment of Child and Adolescent Anxiety Disorders, CBT
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Yale University
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Social Anxiety Disorder, Separation Anxiety Disorder
Stepped Versus Stratified Care for Anxiety Disorders in Youth
The goal of this clinical trial is to compare stepped care to stratified care as overall healthcare models for children and adolescents aged 8-17 with anxiety disorders.
- Conditions
- Social Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Panic Disorder
- Trial name
- NCT06942429
- Testing
- Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 556 people
- Sponsor
- Region Skane
Separation Anxiety Disorder, Generalized Anxiety Disorder
Modular Cognitive Behavioral Therapy for the Treatment of Child Anxiety Disorders in Elementary School Settings
Although cognitive behavioral therapy (CBT) has been found to be efficacious in the treatment of child anxiety disorders, little progress has been made in the dissemination of such treatments to real-world practice settings.
- Conditions
- Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia
- Trial name
- KATES (NCT00569829)
- Testing
- cognitive behavioral therapy
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Anxiety Disorders, Social Anxiety Disorder
Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety
Anxiety is among the most prevalent, costly and disabling illnesses and tends emerge early in childhood. Cognitive behavioral therapy (CBT) is the first-line treatment for early life anxiety, but as many as 40% of young patients…
- Conditions
- Anxiety Disorders, Social Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder
- Trial name
- Anxiety-CBT (NCT02810171)
- Testing
- Cognitive Behavioral Therapy, Relaxation Therapy
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Separation Anxiety
Effects on Recovery of Children of Intravenous Formulation of Fentanyl Citrate and Midazolam Orally for Premedication
To study and compare the efficacy of intravenous formula of fentanyl citrate and midazolam administered orally for premedication in paediatric surgical patients.
- Trial name
- NCT05500599
- Testing
- Fentanyl Citrate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Social Phobia, Generalized Anxiety Disorder
Brain Markers of Anxiety Disorders and SSRI/CBT Treatment in Children and Adolescents
This study will attempt to identify gene and brain activity markers that predict whether children and adolescents with anxiety disorders will respond to selective serotonin reuptake inhibitor medications or Cognitive Behavioral…
- Conditions
- Social Phobia, Generalized Anxiety Disorder, Separation Anxiety Disorder
- Trial name
- NCT01160588
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety, Separation, Anxiety, Generalized
Partners in Caring for Anxious Youth
Pediatric onset anxiety disorders (generalized anxiety, social anxiety, separation anxiety) are highly prevalent, and if untreated, are impairing into adolescence and adulthood.
- Conditions
- Anxiety, Separation, Anxiety, Generalized, Anxiety, Social
- Trial name
- PCAY (NCT04598230)
- Testing
- Cognitive Behavioral Therapy (CBT), Combination therapy (COMB)
- Where
- 3 sites in United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Obsessive-compulsive Disorder, Social Phobia
Brief Behavioral Treatment for Anxiety in Young Children
Behaviorally and cognitive-behaviorally based therapeutic techniques (BT; CBT) that incorporate exposure therapy useful for treatment of anxiety disorders among typically developing children.
- Conditions
- Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia
- Trial name
- PLET (NCT02051192)
- Testing
- Parent-Led Exposure Therapy, Treatment As Usual
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of South Florida
Anxiety Disorders, Social Phobia
Child and Adolescent Anxiety Disorders (CAMS)
This randomized, controlled trial compared the efficacy of the medication sertraline (Zoloft®), cognitive-behavioral therapy, the combination of these treatments, and placebo for youth with anxiety disorders.
- Conditions
- Anxiety Disorders, Social Phobia, Generalized Anxiety Disorder
- Trial name
- NCT00052078
- Testing
- Sertraline (SRT), Cognitive Behavioral Therapy (CBT)
- Where
- 6 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University