Clinical trials: Severe Obesity
Morbid Obesity, Cardiovascular Disease
Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment
The purpose of this study is to determine the concentration of omega-3 fatty acids in plasma, blood and abdominal fat before and after bariatric surgery to provide guidance for future studies.
- Conditions
- Morbid Obesity, Cardiovascular Disease, Fatty Acid Levels
- Trial name
- NCT00558532
- Testing
- Bariatric Surgery
- Where
- United States
- Sponsor
- University of Cincinnati
Morbid Obesity
Neurohumoral Control of Intestinal Electrical and Mechanical Activity
A collaborative research project with Dr. Kathleen Keef (Department of Physiology, University of Nevada School of Medicine, Reno, Nevada) studying the role of putative neurotransmitters in human intestine.
- Trial name
- NCT00852553
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of California, Davis
Obesity, Surgery
Laparoscopic Sleeve Gastrectomy in Severely Obese Adolescents: Effects on Metabolism
Severe obesity (SO), defined as BMI≥95th percentile, has increased worldwide among adolescents. American studies estimated that 1.3-2.8% of 12-19-year-old individuals have a BMI >40 kg/m2 or a BMI >35 kg/m2 with at least one…
- Trial name
- NCT02594514
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo General Hospital
Pro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene Mutations
Genetic Testing and Phenotypic Characterization of Severely Obese Pediatric and Adult Volunteers
The purpose of this screening study is to identify people who have a rare genetic cause of obesity - specifically three genetic variants (a change in the DNA structure) of the POMC, PCSK1 and LepR genes that are currently known…
- Trial name
- NCT02849977
- Where
- 58 sites in United States, Canada and 5 more
- Volunteers
- 5,966 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Morbid Obesity
Effect of Gastric Balloon in Morbid Obesity: Prospective Study
The aim of this study is to compare the efficacy of gastric balloon in weight reduction among two different categories of morbidly obese people.
- Trial name
- NCT02128165
- Testing
- BMI more than 45 BMI, BMI less than 45 BMI
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Obesity, Extreme Obesity
Identification and Characterization of Youth With Extreme Obesity
While obese and extremely obese youth are at increased risk of health complications, especially the extremely obese group rarely seek medical care. One of the underlying reasons might be the lack of adequate treatment options.
- Trial name
- YES (NCT01625325)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Severe Obesity
Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass
The purpose of this study is to examine the effects of bile acids on GLP-1 secretion after Roux-en-Y gastric bypass.
- Trial name
- NCT02340247
- Testing
- Water, Ursodeoxycholic Acid, Chenodeoxycholic Acid
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital