Clinical trials: Sexual Behavior
HIV Infection
Impact of a Human Papilloma Virus (HPV) Vaccine in HIV-Infected Young Women
The purpose of this study is to evaluate the immunogenicity, safety, tolerability, and behavioral impact of an HPV-6, -11, -16, -18 vaccine in HIV-infected young women.
- Trial name
- NCT00710593
- Testing
- HPV vaccine for strains -6, -11, -16, and -18
- Where
- 14 sites in United States, Puerto Rico
- Volunteers
- 99 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV (Human Immunodeficiency Virus), Alcohol Misuse
PNF RCT to Decrease Alcohol Use and Increase HIV Prevention
Randomized controlled trial to test the preliminary efficacy and mediating mechanism of a personalized normative feedback intervention on behavioral intentions, heavy alcohol use, and HIV/STI prevention among adolescents and…
- Conditions
- HIV (Human Immunodeficiency Virus), Alcohol Misuse, STI
- Trial name
- NCT07731932
- Testing
- PNF - HIV norms, PNF - Alcohol use norms, PNF - HIV and alcohol use norms
- Where
- Uganda
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Attempted Rape of Female
Medico-legal Assessment of Sexual Violence-Assiut University
Medico legal assessment of sexual assaults allegations of females presented to hospital and any associated violence. Assessment of cases of pregnancy associated violence with other related complications that have both medical and…
- Trial name
- NCT05399563
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hypothalamic Obesity, Prader-Willi Syndrome
A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment
The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairment
- Conditions
- Hypothalamic Obesity, Prader-Willi Syndrome, PWS
- Trial name
- NCT06239116
- Testing
- Part C: RM-718, Part D: RM-718
- Where
- 7 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Sexual and Reproductive Health
Electronic Sexual Reproductive Health CDS Tool at the Children's Hospital of Philadelphia
Many studies show early detection of sexual activity in adolescents can improve their health management and that primary care pediatricians would benefit from supports to address adolescent health, including sexual and…
- Trial name
- NCT04974086
- Testing
- Sexually transmitted infection (STI) testing clinical decision support (CDS) tool
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Comprehensive Sexual Education
What Works to Prevent Violence Against Women and Girls in Madagascar
The study will evaluate a comprehensive sexual education program (CSE) delivered by Projet Jeune Leader (PJL), a women-led non-governmental program in Madagascar.
- Trial name
- NCT06598553
- Testing
- Projet Jeune Leader Comprehensive Sexual Education
- Where
- Madagascar
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hypothalamic Obesity
Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity
The proposed multicenter study will test the effect of glucagon-like peptide (GLP)-1 agonist exenatide once weekly extended-release (ExQW, Bydureon®) on clinical outcomes and metabolic parameters in a double-blind…
- Trial name
- ECHO (NCT02664441)
- Testing
- Exenatide
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Seattle Children's Hospital
Post Traumatic Stress Disorder, Anxiety
National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database
Trauma-informed treatment will improve emotional regulation and behavior.
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression, Conduct Disorder
- Trial name
- NCT01591694
- Where
- United States
- Volunteers
- 4,193 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Contraception Behavior, Sexual Behavior
Evaluating the Impact of CHOICE-AYA on Contraceptive Use, Continuation and Satisfaction
This is a prospective study involving two phases: 1) adaptation and 2) intervention, in adolescents aged 14-21 experiencing homelessness.
- Conditions
- Contraception Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- CHOICE-AYA (NCT05022134)
- Testing
- CHOICE-AYA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
HIV Infections, Men
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two…
- Conditions
- HIV Infections, Men, Treatment Adherence
- Trial name
- NCT05602376
- Testing
- U=U testing messaging scripts, U=U adherence messaging scripts
- Where
- 2 sites in South Africa
- Volunteers
- 3,642 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Fatigue Recovery, Basketball
Neuromuscular Effects of Acute Fatigue in Adolescent Basketball
The primary aim of this study is to investigate the effects of acute fatigue on neuromuscular control and performance parameters in professional adolescent basketball players and to determine the relationship between fatigue…
- Conditions
- Fatigue Recovery, Basketball, Gender, Neuromuscular Control
- Trial name
- NCT07467525
- Testing
- basketball practice
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Severe Malaria, Uncomplicated Malaria
Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX
Understanding the sexual conversion of the malaria parasite is essential to interrupt malaria transmission. A new tool is developed that, based on expression analysis of sexual stage biomarkers, will estimate sexual conversion…
- Conditions
- Severe Malaria, Uncomplicated Malaria, Asyptomatic Plasmodium Infection
- Trial name
- IMMETASEX (NCT06064591)
- Where
- 3 sites in Belgium, Burkina Faso and 1 more
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Sexual Violence
Preventing Sexual Violence Among Middle School Boys With a Strengths-Based Curriculum
This research will examine if participation in a strengths-based curriculum, the Brothers as Allies program adapted from the Council for Boys and Young Men, reduces risk for future sexual violence perpetration among middle…
- Trial name
- NCT03392597
- Testing
- Brothers as Allies, Programming-as-Usual
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- New York State Department of Health
Pediatric Cardiac Surgery, Gender
Gender Influence on Morbi-mortality in Pediatric Cardiac Surgery.
Recent studies show an important influence of gender on inflammatory reactions. Cardiac surgery is associated with a major systemic inflammatory response.
- Trial name
- NCT04452539
- Testing
- Paediatric cardiac surgery
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- Brugmann University Hospital
Anxiety Symptoms, Depressive Symptoms
Universal Preventive Resilience Intervention to Improve and Promote Mental Health for Teenagers
Adolescence is a period of many physical, mental, emotional, and social changes. It is also associated with risk behaviour conducts.
- Conditions
- Anxiety Symptoms, Depressive Symptoms, Behavioral Problem of Child, Mental Disorder in Adolescence
- Trial name
- UPRIGHT (NCT03951376)
- Testing
- UPRIGHT intervention
- Where
- 5 sites in Denmark, Iceland and 3 more
- Volunteers
- 4,460 people, healthy volunteers welcome
- Sponsor
- Biosistemak Institute for Health Systems Research
Sexuality
Randomized Controlled Trial of a Gender-transformative School-based Sexual Health Intervention
The goal of this randomized controlled trial (RCT) is to evaluate the effectiveness of a comprehensive gender-transformative intervention of sexual education (ENFOCATE -Focus-on) in adolescents, using a mixed experimental design.
- Trial name
- ENFOCATE (NCT05896540)
- Testing
- ENFOCATE
- Volunteers
- 609 people, healthy volunteers welcome
- Sponsor
- University of Chile
Sexually Transmitted Diseases, Sexually Transmitted Diseases, Viral
Psychoeduc Interv. Through Meta-universes on Condom's Use Self - Efficacy and Sexual Behavior in Students of UAChile
In Chile, sexually transmitted infections (STI)s, including HIV / AIDS, are the main causes of morbidity in adolescents and young adults.
- Conditions
- Sexually Transmitted Diseases, Sexually Transmitted Diseases, Viral, Sexually Transmitted Diseases, Bacterial
- Trial name
- MVSR (NCT03684668)
- Testing
- Psychoeducational intervention
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- Rosa Jimenez
Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity
Background: Androgen effects in humans are usually (but not always) mediated by the androgen receptor which is coded for by the androgen receptor gene (AR gene).
- Conditions
- Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS, Tumor Formation in AIS, CAIS, PAIS and MAIS, Sexual Function AIS, CAIS, PAIS and MAIS
- Trial name
- NCT04708431
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV, Substance Use Disorders
The Collaborative Care PrTNER Study
A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk…
- Conditions
- HIV, Substance Use Disorders, Substance Use, AIDS
- Trial name
- PrTNER (NCT06585631)
- Testing
- CC PrTNER
- Where
- 2 sites in United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Sexual Behavior, Unprotected Sex
Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care Intervention
The aim of this research protocol is to test the efficacy of a self-care intervention through a randomized controlled trial (RCT), for increasing protective sexual health behaviors among youth in the participating Native American…
- Conditions
- Sexual Behavior, Unprotected Sex, Gonorrhea, Chlamydia
- Trial name
- NCT03895320
- Testing
- Sexual Health Risk Assessment, Sexual Health Score, Sexual Health Messaging
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health