Clinical trials: Sexual Dysfunctions
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Cancer Survivor, Depression
Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer
RATIONALE: Telephone counseling after radical prostatectomy may help African American prostate cancer survivors and their intimate partners cope with the problems and challenges of surgery, and may reduce distress and improve…
- Conditions
- Cancer Survivor, Depression, Gastrointestinal Complications, Male Erectile Disorder
- Trial name
- NCT00869739
- Testing
- telephone-based intervention, educational intervention, partner-assisted coping skills training
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Dyspareunia
Effect of Radiofrequency in the Treatment of de Novo Dyspareunia at 4 to 12 Months Postpartum.
This study evaluates if the application of resistive capacitive monopolar radiofrequency therapy associated with Thiele massage is effective when treating de novo dyspareunia at 4 to 12 months postpartum.
- Trial name
- NCT05417334
- Testing
- Resistive Capicitive Monopolar Radiofrequency
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Clinic of Barcelona
Gender Dysphoria
Chest Dysphoria in Transmasculine Spectrum Adolescents
The investigators hypothesize that masculinizing top surgery (e.g., mastectomy and chest masculinization) leads to an improvement in self-report chest dysphoria, gender dysphoria, and gender congruence in…
- Trial name
- NCT04195659
- Testing
- Mastectomy and chest masculinization
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Northwestern University
Gender Dysphoria, Gender Identity Disorder
TransCare - Genital Surgery for Trans Women in Centralized vs. Decentralized Health Care Delivery Settings
Trans (i.e., transgender, transsexual) individuals experience a gender that does not match their sex assigned at birth (Gender Incongruence), which can lead to distress called gender dysphoria (formerly known as transsexualism).
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT03872648
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Post Traumatic Stress Disorder, Rape Sexual Assault
Early Psychological Intervention After Rape
Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape.
- Conditions
- Post Traumatic Stress Disorder, Rape Sexual Assault, Sexual Dysfunctions, Psychological, Pelvic Floor Myalgia
- Trial name
- EIR (NCT05489133)
- Testing
- Modified prolonged exposure
- Where
- 4 sites in Norway
- Volunteers
- 166 people
- Sponsor
- St. Olavs Hospital
Genitourinary Syndrome of Menopause, Vaginal Atrophy
Vaginal Laser Therapy in Breast Cancer Survivors
This study evaluates the efficacy of vaginal CO2 laser therapy in breast cancer survivors with symptoms of Genitourinary Syndrome of Menopause.
- Conditions
- Genitourinary Syndrome of Menopause, Vaginal Atrophy, Breast Cancer, Dyspareunia
- Trial name
- NCT03738605
- Testing
- Microablative Fractional CO2 Laser Therapy
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Vaginismus
Spinal Anesthesia Facilitated Sexual Intercourse As A Treatment Option For Vaginismus
Painful sex continues to be a relationship issue and can lead to marital dys-harmony. Other consequences include infertility, low self-esteem, depression and anxiety.Our study shows that spinal anesthesia is an effective last…
- Trial name
- NCT04436172
- Testing
- spinal anesthesia
- Volunteers
- 20 people
- Sponsor
- Karachi Medical and Dental College
Erectile Dysfunction
Blood Types and Erectile Dysfunction
The researchers aimed to investigate the relationship between ABO blood types and erectile dysfunction.
- Trial name
- NCT02454946
- Volunteers
- 102 people
- Sponsor
- Ordu University
Erectile Dysfunction
Effects of Yohimbine and Naltrexone on Sexual Function
The purpose of this study is to evaluate the safety and effectiveness of the drugs yohimbine and naltrexone in treating men with erectile dysfunction (ED) (the inability to achieve or maintain penile erection for satisfactory…
- Trial name
- NCT00042536
- Testing
- Naltrexone HCL/ Yohimbine HCL
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Impulsive Behavior, Impulse Disorders
Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
The objective of this prospective observational cohort study is to answer the following clinically important questions: 1. In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration…
- Conditions
- Impulsive Behavior, Impulse Disorders, Gambling, Pathological, Eating, Binge
- Trial name
- CRIPS (NCT04811807)
- Testing
- Subthalamic Nucleaus Deep brain stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Ovariectomy, Hysterectomy
Surveillance Study of Women Taking Intrinsa®
The primary objective of the study is to assess the risks of testosterone transdermal patch use in a representative study population. The primary clinical outcome of interest is breast cancer.
- Conditions
- Ovariectomy, Hysterectomy, Hypoactive Sexual Desire Disorder
- Trial name
- EMPOWER (NCT00551785)
- Where
- Germany
- Volunteers
- 328 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Cervical Carcinoma, Dyspareunia
Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors
This randomized pilot trial studies how well fractional carbon dioxide (CO2) laser therapy works in minimizing genitourinary syndrome of menopause (GSM) in gynecological cancer survivors.
- Conditions
- Cervical Carcinoma, Dyspareunia, Endometrial Carcinoma, Ovarian Carcinoma
- Trial name
- NCT03372720
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Female Genital Mutilation, Sexual Dysfunctions, Psychological
Sexual Health of Women With Genital Mutilation Seen at the Saint-Denis Women's Center
This study looks at the sexual health of women who have experienced female genital mutilation (FGM) and who are receiving care at the Women's Center at Saint-Denis Hospital.
- Conditions
- Female Genital Mutilation, Sexual Dysfunctions, Psychological, Sexual Health, Violence Against Women
- Trial name
- NCT07027696
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Erectile Dysfunction, Penile Prosthesis; Complications, Infection or Inflammation
Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement
The purpose of this study is to assess whether intraoperative irrigation with Irrisept is not inferior to irrigation with multiple antibiotics during placement of a first time inflatable penile prosthesis device.
- Trial name
- NCT06489431
- Testing
- Chlorhexidine, Gentamicin, Rifampin
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Prostate Cancer
A Couple Support Intervention for Prostate Cancer
Even with careful prostate surgery, men find it difficult to have an erection. Our previous research shows that couples are not often supported to cope with the effects of surgery on their sexual relationships.
- Trial name
- NCT01842438
- Testing
- Behavioral: psychosexual intervention
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- University of Stirling
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Genitourinary Abnormality, Breast Cancer Female
GSM (Genitourinary Syndrome Of Menopause) Management In Breast Cancer Survivors
The impact of treatment for GSM on the quality of life will be examined for postmenopausal women (defined as last menstrual period > 1 year ago or 6 months ago with FSH >40) who have been diagnosed with breast cancer.
- Conditions
- Genitourinary Abnormality, Breast Cancer Female, Vaginal Abnormality, Urinary Tract Infections
- Trial name
- GSM (NCT03185169)
- Testing
- Replens and coconut oil
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Alta Bates Summit Medical Center
Gender Dysphoria
Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering From Gender Dysphoria
Gender dysphoria (GD) is a significant suffering lasting more than 6 months in a subject, with regard to the discrepancy felt between his or her gender identity and his or her birth sex.
- Trial name
- TRANSADO (NCT06351501)
- Testing
- hormonal treatment with cross sex hormones (testosterone or oestrogenes) started at 14 years old +/- 6 months, Cross sex hormones ( œstrogenes or testosterone) started at 15.5 years old +/- 6 months
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris