Clinical trials: Sexuality
Bacterial Infections, Pneumonia, Pneumocystis Carinii
A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children
This study compares 2 different treatments administered to try to prevent serious bacterial infections (such as pneumonia) in HIV-positive children.
- Conditions
- Bacterial Infections, Pneumonia, Pneumocystis Carinii, HIV Infections
- Trial name
- NCT00000811
- Testing
- Azithromycin, Atovaquone, Sulfamethoxazole-Trimethoprim
- Where
- 75 sites in United States, Puerto Rico
- Volunteers
- 690 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Papillomavirus Infections
Safety, Tolerability and Immunogenicity of HPV (Human Papilloma Virus) Vaccine in Healthy Females 9 to 15 Years of Age in India (V501-029)
The purpose of this study is to evaluate the safety and tolerability of the Quadrivalent Human Papilloma Virus (HPV) vaccine in healthy females 9 to 15 years of age in India.
- Trial name
- NCT00380367
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Infections, Papillomavirus
Follow-up Study to Evaluate the Long-term Efficacy of the HPV Vaccine (580299) in Healthy Young Adult Women in Brazil
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. This Phase IIb study is designed to evaluate the the long-term efficacy, safety and immunogenicity of the 580299 HPV…
- Trial name
- NCT00518336
- Testing
- Blood sampling, Collection of cervical specimen, Cervarix
- Where
- 5 sites in Brazil
- Volunteers
- 433 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infection, Tuberculosis
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV
Tuberculosis (TB) is highly endemic in sub-Saharan Africa. The increased burden of TB in settings with high prevalence of the Human Immunodeficiency Virus (HIV) is associated with high rates of transmission of Mycobacterium…
- Conditions
- HIV Infection, Tuberculosis, Pneumocystis Jiroveci Pneumonia
- Trial name
- NCT00080119
- Testing
- Isoniazid (INH), Trimethoprim/Sulfamethoxazole (TMP/SMX)
- Where
- 6 sites in Botswana, South Africa
- Volunteers
- 1,354 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
HIV Infections
HIV Symptom Management Program for African American Mothers
African American mothers infected with HIV face unique challenges in management of their disease. The goal of this study was to determine the effectiveness of an HIV self-care and symptom management program designed to help…
- Trial name
- NCT00065819
- Testing
- HIV Symptom Education Program
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Fragile X Syndrome
Optical Imaging as a Tool for Monitoring Brain Function in Fragile X Syndrome
The objective of this project is to explore the potential of functional near- infrared spectroscopy (fNIRS) as innovative functional biomarker for clinical trial readiness in Fragile X Syndrome (FXS) that is still without cure.
- Trial name
- NCT06293027
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
HIV Infections
Evaluation of the Performance of Chembio Diagnostics Systems, Inc. DPP® HIV 1/2 Rapid Test
This study has been designed to evaluate the performance of the Chembio Diagnostics Systems, Inc. DPP® HIV 1/2 rapid test. The device is intended to qualitatively detect the presence of antibodies against HIV-1/2 in oral fluid…
- Trial name
- NCT01032902
- Testing
- In Vitro Diagnostic Device
- Where
- 5 sites in United States
- Volunteers
- 2,808 people, healthy volunteers welcome
- Sponsor
- Chembio Diagnostic Systems, Inc.
Pregnancy, Malaria
Safe Pregnancy by Infectious Disease Control
Malaria and sexually transmitted infections (STIs) are common in pregnant women in Africa and are important preventable causes of poor birth outcomes and maternal and infant mortality.
- Trial name
- NCT00489619
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 2,008 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Pregnancy Prevention, Sexual Behavior
Project Legacy Impact Evaluation Study
This study will design and rigorously evaluate the efficacy of Project Legacy, a five week positive youth development intervention to decrease sexual risk for unintended pregnancies and STIs among youth experiencing homelessness…
- Conditions
- Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
- Trial name
- NCT03366636
- Testing
- Project Legacy
- Where
- 12 sites in United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Bond, Pair
Comparison of 3D Printed Metal Fixed Retainer Versus Conventional Fixed Bonded Retainer
Despite the growing diversity of materials used for mandibular fixed retainers, the evidence base remains inconclusive. In particular, conflicting findings have been reported regarding the bond failure of titanium retainers…
- Trial name
- NCT07538869
- Testing
- bar 3d printed metal fixed retainer, conventional fixed retainer
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Amany Ibrahim
Sexual Violence
ConnectEd: A Randomized Controlled Trial Connecting Through Educational Training
The purpose of this randomized intervention pilot is to evaluate the relative efficacy of bystander training elements (delivery mode and integration of substance abuse prevention) among cohorts of incoming undergraduates at the…
- Trial name
- ConnectEd (NCT02786472)
- Testing
- Online Bystander Training, Online Substance Abuse Training, In-Person Bystander Training
- Where
- United States
- Volunteers
- 3,178 people, healthy volunteers welcome
- Sponsor
- Heather Bush
HIV/AIDS
REMUNE HIV/AIDS Vaccine Phase II Pediatric Safety & Efficacy Clinical Study
The primary objective is to compare \& evaluate between the treatment groups the changes in decline/reduction of HIV viral load \& increase changes in WBC white blood cell counts in the adult Remune dose vs the low dose Remune…
- Trial name
- NCT02291809
- Testing
- REMUNE
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Immune Response BioPharma, Inc.
CMV Viremia, CMV Disease
Expanded Access Protocol of ATA230 (Third-Party Donor-Derived CMV-CTLs) for the Treatment of CMV Viremia or Disease
This is an expanded access protocol designed to provide access of ATA230 to subjects with cytomegalovirus (CMV) viremia or disease, who are intolerant to, or failed, standard antiviral therapy and have no comparable treatment…
- Trial name
- NCT03010332
- Testing
- Cytomegalovirus-specific Cytotoxic T Lymphocytes (CMV-CTLs)
- Sponsor
- Atara Biotherapeutics
HIV/AIDS, STD
A Computer-Based Parent/Adolescent HIV Communication Intervention for Latinos
The purpose of this study is to examine the efficacy of a brief culturally appropriate and theory-based parental communication intervention designed to improve parent-adolescent sexual communication and reduce adolescent sexual…
- Conditions
- HIV/AIDS, STD, Pregnancy
- Trial name
- NCT01084421
- Testing
- Computer-based parent-adolescent HIV communication
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Kidney Failure, AIDS-Associated Nephropathy
Prevalence of Proteinuria and Chronic Kidney Disease in Pediatric HIV-Infected Patients
Among adults with Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS), Chronic Kidney Disease (CKD) has previously been reported to occur in approximately 10% of children with HIV-infection.
- Conditions
- Chronic Kidney Failure, AIDS-Associated Nephropathy, HIV Infections
- Trial name
- NCT00153621
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Children's National Research Institute
HIV Positive, Malnourished
IMPAACT P1092: Steady State PK in Malnourished HIV Infected Children
Children living with HIV from sub-Saharan Africa often present with severe malnutrition. In severe malnutrition, metabolic and/or gut structural derangement may lead to inadequate antiretroviral (ARV) absorption and/or erratic…
- Trial name
- NCT01818258
- Testing
- ZDV+3TC+LPV/r
- Where
- 5 sites in Malawi, Tanzania and 2 more
- Volunteers
- 52 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
HIV Infections
Outcomes of Anti-HIV Therapy During Early HIV Infection
The purpose of this study is to find out if it is effective to give aggressive anti-HIV therapy to patients who have been infected recently with HIV.
- Trial name
- NCT00001093
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sexually Transmitted Diseases
A Case Control Study of Women With Multiple Sexual Partners
Both population based surveys and more focused research studies indicate that increased numbers of sexual partners and partner concurrency contribute to increased risk for acquisition of sexually transmitted infection (STI)…
- Trial name
- NCT01578915
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Carcinoma, Cancer Survivor
Fractional CO2 Laser Therapy for Survivors of Breast Malignancies
This pilot clinical trial studies how well fraction carbon dioxide (CO2) laser therapy works in treating vaginal atrophy in patients with breast cancer.
- Conditions
- Breast Carcinoma, Cancer Survivor, Cervical Carcinoma, Dyspareunia
- Trial name
- NCT03307044
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
HIV (Human Immunodeficiency Virus), Alcohol Misuse
PNF RCT to Decrease Alcohol Use and Increase HIV Prevention
Randomized controlled trial to test the preliminary efficacy and mediating mechanism of a personalized normative feedback intervention on behavioral intentions, heavy alcohol use, and HIV/STI prevention among adolescents and…
- Conditions
- HIV (Human Immunodeficiency Virus), Alcohol Misuse, STI
- Trial name
- NCT07731932
- Testing
- PNF - HIV norms, PNF - Alcohol use norms, PNF - HIV and alcohol use norms
- Where
- Uganda
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
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