Clinical trials: Sexually Transmitted Infection (STI)
Anogenital Human Papilloma Virus Infection
Comparison Between Efficacy of Topical 25%Podophyllin and Cryotherapy on Genital Warts
Human papilloma virus (HPV), is the major prevalent cause of sexually transmitted disease affecting genitalia, causing Condylomata Accuminata, also known as external genital warts or anogenital warts.¹ Occurring in men and women…
- Trial name
- NCT06809777
- Testing
- Topical 25% podophyllin, Cryotherapy
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Sheikh Zayed Medical College
HIV Infections
HIV Symptom Management Program for African American Mothers
African American mothers infected with HIV face unique challenges in management of their disease. The goal of this study was to determine the effectiveness of an HIV self-care and symptom management program designed to help…
- Trial name
- NCT00065819
- Testing
- HIV Symptom Education Program
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Papillomavirus Infections
Human Papillomavirus (HPV) Registration Study (Gardasil)(V501-023)(COMPLETED)
This is an immunogenicity and safety study of Gardasil (V501) in females 9 to 23 years of age in Korea.
- Trial name
- NCT00157950
- Testing
- Gardasil™
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections
A Study of Enfuvirtide (Fuzeon) in Patients With Advanced Human Immunodeficiency Virus-1 (HIV-1) Infection
This study will evaluate the safety and tolerability of subcutaneous Fuzeon in patients with advanced HIV-1 infection unable to construct an appropriate treatment regimen from currently available antiretroviral agents.
- Trial name
- NCT02569502
- Testing
- enfuvirtide
- Where
- Bulgaria
- Volunteers
- 6 people
- Sponsor
- Hoffmann-La Roche
HIV (Human Immunodeficiency Virus), Chlamydia
Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland
The main goal of the observational study is to evaluate participants' satisfaction with free HIV and sexually transmitted infection (STI) testing and counselling offered by the cities of Lucerne and Zurich, Switzerland to young…
- Conditions
- HIV (Human Immunodeficiency Virus), Chlamydia, Gonorrhea, Syphilis
- Trial name
- feSTI (NCT07516912)
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Zurich
HIV Infections
Pilot Study to Evaluate the Efficacy of Zidovudine in Preventing CD4+ Lymphocyte Decline in Patients With Primary HIV Infection. (One Treatment Arm Receives Placebo)
To evaluate the safety and efficacy of early treatment with zidovudine for preventing a decline in CD4+ lymphocyte counts in patients with primary HIV infection.
- Trial name
- NCT00000765
- Testing
- Zidovudine
- Where
- 9 sites in United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Mental Health
Stepped Care for Youth Living With HIV
Optimizing the HIV Treatment Continuum with a Stepped Care Model for Youth Living with HIV (YLH) aims to achieve viral suppression among YLH.
- Conditions
- HIV, Mental Health, Illicit Substance Use, Sexually Transmitted Infections (STI)
- Trial name
- NCT03109431
- Testing
- Level 1, Level 2, Level 3
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tuberculosis, HIV Infections
Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)
HIV-infected people have an increased risk of developing active tuberculosis (TB). At the time the study was designed, the standard course of treatment for TB was 6 to 9 months of isoniazid (INH).This study compared the safety…
- Trial name
- NCT01404312
- Testing
- Rifapentine (RPT), Isoniazid (INH), Pyridoxine (Vitamin B6)
- Where
- 45 sites in United States, Botswana and 8 more
- Volunteers
- 3,000 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Treponema Pallidum Infection, Chlamydia Trachomatis Infection
Improving Maternal and Child Health Through Point-of-care STI Testing
The goal of this clinical trial is to learn if point-of-care tests (POCTs) for sexually transmitted infections (STIs) improve the timely treatment of syphilis, chlamydia, gonorrhea, and trichomonas in pregnant women.
- Conditions
- Treponema Pallidum Infection, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginalis Vaginitis
- Trial name
- MATCH-POINT (NCT07290439)
- Testing
- Point-of-care STI tests, Standard of care STI testing
- Where
- United States
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections, AIDS
Test Albuvirtide in Experienced Patients
The purpose of this study is to evaluate the efficacy and safety of albuvirtide combined with lopinavir-ritonavir (LPV/r) in HIV-1-infected patients who failed first-line antiretroviral therapy (ART).
- Trial name
- TALENT (NCT02369965)
- Testing
- albuvirtide, lopinavir-ritonavir, tenofovir
- Where
- 12 sites in China
- Volunteers
- 418 people
- Sponsor
- Frontier Biotechnologies Inc.
HIV Infections
A Comparison of Zidovudine (AZT) and Stavudine in HIV-Infected Patients
To compare stavudine (d4T) and zidovudine (AZT) in slowing the progression of HIV disease. To compare the antiviral activity of d4T versus AZT as measured by plasma levels of p24 antigen and HIV viremia, and their relative…
- Trial name
- NCT00002307
- Testing
- Stavudine, Zidovudine
- Where
- 45 sites in United States, Puerto Rico
- Sponsor
- Bristol-Myers Squibb
HIV Infections
A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT
To evaluate and compare the long-term (48-177 weeks) safety, tolerance, and efficacy of two doses of zalcitabine ( dideoxycytidine; ddC ) taken orally every 8 hours in children with symptomatic HIV infection who have one of the…
- Trial name
- NCT00000653
- Testing
- Zalcitabine
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 140 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sexual Risk Behavior, Drug Use
eHealth Evidence-based Intervention (EBI) for Latino Youth in Primary Care
The purpose of this study is to test the relative effectiveness of a Hispanic-specific eHealth intervention, "e-Health Familias Unidas," in preventing and reducing drug use, sexual risk behaviors, and STIs among Hispanic youth in…
- Conditions
- Sexual Risk Behavior, Drug Use, Family Functioning
- Trial name
- NCT03009539
- Testing
- eHealth Familias Unidas Primary Care
- Where
- 12 sites in United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV Infections
Endothelial Dysfunction as a Risk Factor in HIV Study
Highly active antiretroviral therapy (HAART) has proven effective in altering the natural history of HIV infection in many patients. However, this therapy may not be sustainable because of the toxicities of the medications.
- Trial name
- NCT00039663
- Testing
- Pravastatin, Gemfibrozil, Rosiglitazone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Infection
Identigene STD Test Collection Kit Validation Study
The overall goal of the present study is to provide evidence of concordant test results using the Identigene STD Test Collection Kit for self-collection and transport of specimens to a qualified testing laboratory.
- Trial name
- NCT01471392
- Testing
- STD Diagnostic Kit (Identigene)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Identigene
Pregnancy Related, Sexually Transmitted Diseases
Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth
This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program.
- Conditions
- Pregnancy Related, Sexually Transmitted Diseases, Adolescent Behavior
- Trial name
- Yes and Know (NCT06581536)
- Testing
- Yes and Know curriculum, Nutrition Education for Adolescents
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- ETR Associates
HIV Infections
Evaluation of the Performance of Chembio Diagnostics Systems, Inc. DPP® HIV 1/2 Rapid Test
This study has been designed to evaluate the performance of the Chembio Diagnostics Systems, Inc. DPP® HIV 1/2 rapid test. The device is intended to qualitatively detect the presence of antibodies against HIV-1/2 in oral fluid…
- Trial name
- NCT01032902
- Testing
- In Vitro Diagnostic Device
- Where
- 5 sites in United States
- Volunteers
- 2,808 people, healthy volunteers welcome
- Sponsor
- Chembio Diagnostic Systems, Inc.
Neisseria Gonorrheae Infection
Master Protocol for Evaluating Multiple Infection Diagnostics for Ciprofloxacin-Resistant Neisseria Gonorrhoeae
The goal of this study is to learn if a few investigational tests can correctly find the gene mutation (mutant allele gyrA 91F) that predicts ciprofloxacin resistance in clinical specimens that harbor Neisseria gonorrhoeae.
- Trial name
- MASTERMINDRING (NCT06815536)
- Testing
- Investigational Reflex Test 1, Investigational Reflex Test 2, Investigational Reflex Test 3
- Where
- 8 sites in United States
- Volunteers
- 2,627 people
- Sponsor
- Duke University
HIV Infection
Engaging Care for HIV-infected Adolescent Females.
The proposed multi-site, longitudinal study will examine the correlation of substance use, mental health disorders, and social networks to engagement in care for HIV-infected adolescent females, aged 13 years, 0 months - 23…
- Trial name
- NCT00489034
- Testing
- Quantitative Interview, Ethnographic Interview, Gender Interview
- Where
- 5 sites in United States
- Volunteers
- 178 people
- Sponsor
- University of North Carolina, Chapel Hill
Human Immunodeficiency Virus, HIV
Nevirapine Dosing in Neonates for Prophylaxis of Mother-to-Child-Transmission (MTCT) of HIV Infection
The purpose of this study is to determine whether the current dose of nevirapine recommended in the Ontario Ministry of Health vertical transmission prevention protocol achieves therapeutic drug levels in newborn infants at high…
- Conditions
- Human Immunodeficiency Virus, HIV, Vertical Infection Transmission
- Trial name
- NCT02166502
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
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