Clinical trials: Sexually Transmitted Infection Risk
HIV Infections
A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection
AMENDED: As of 10/19/90 only Children 0 to 3 months are being enrolled. Original design: To determine whether the experimental drug recombinant CD4 (rCD4), which is produced through genetic engineering technology, is safe and…
- Trial name
- NCT00000984
- Testing
- CD4 Antigens
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Substance Abuse
Young Women's Health CoOp (Cooperative) in Cape Town
This supplement study is an adaptation of the larger NIH-funded parent study, the Women's Health CoOp+, which tests a combination biobehavioral HIV prevention approach to enhance standard HIV testing practices for alcohol and…
- Trial name
- YWHC (NCT02677025)
- Testing
- Young Women's Health CoOp (YWHC), HIV Counseling/Testing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RTI International
In Utero Drug Exposure
Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero
The Human Immunodeficiency Virus (HIV) has been recently linked to increased risk for cardiovascular diseases (CVDs). The prevalence of cardiovascular diseases and its risk factor, hypertension, are very high in African…
- Trial name
- ARTMOMSBABES (NCT04763668)
- Testing
- Pregnant HIV positive women on ARTs, Babies born to HIV positive mothers on ARTs
- Where
- South Africa
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Walter Sisulu University
HIV Infections, Sexually Transmitted Disease
Effect of HIV/STD Risk Reduction Program on South African Adolescents
This study will evaluate the effect of an HIV/STD risk-reduction program on the sexual behavior of South African adolescents.
- Trial name
- NCT00559403
- Testing
- HIV/STD Risk-Reduction, Health Promotion
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV-infection/Aids, Intimate Partner Violence
Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention
This study will develop and pilot test a couples-based intervention to help adolescent girls and young women living with HIV (WLHIV (15-24 years) living in Uganda access HIV care and improve the outcomes of their HIV treatment by…
- Conditions
- HIV-infection/Aids, Intimate Partner Violence, Domestic Violence, Alcohol Use Disorder
- Trial name
- NCT05947539
- Testing
- Kisoboka Mukwano ("It is possible, my love!") Intervention, Screening and Referral
- Where
- Uganda
- Volunteers
- 80 people
- Sponsor
- Arizona State University
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
HIV-infection/Aids
Healthy Teen Girls: HIV Risk Reduction
This project assesses the efficacy of an HIV prevention program with adolescent females incarcerated in the Mississippi training school for girls.
- Trial name
- NCT00787696
- Testing
- Cognitive-behavioral HIV/STD risk reduction
- Where
- United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Mississippi State University
Sexual Risk Behavior, Sexually Transmitted Infections
Optimizing the Floreciendo Sexual and Reproductive Health Workshop for Latina Teens and Female Caregivers: A Pilot
Floreciendo is a sexual and reproductive health workshop for Latina teens (ages 14-18 years) and their female caregivers (e.g., mothers, sisters, grandmothers).
- Conditions
- Sexual Risk Behavior, Sexually Transmitted Infections, Unplanned Pregnancy
- Trial name
- Floreciendo (NCT06223165)
- Testing
- Floreciendo (Foundations, Condoms & Contraception, Family Strengthening, and Gender & Relationships), Floreciendo (Foundations, Condoms & Contraception, and Family Strengthening), Floreciendo (Foundations, Condoms & Contraception, Gender & Relationships)
- Where
- 4 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Human Immunodeficiency Virus (HIV)
ComBaCaL HIV Prevention TwiCs
This cluster-randomized intervention is embedded in the ComBaCaL (Community-Based Chronic disease care Lesotho) cohort study (EKNZ ID AO_2022-00058, clinicaltrials.gov ID NCT05596773, Lesotho NH-REC ID 210-2022), a platform for…
- Trial name
- CoPrev (NCT07581600)
- Testing
- CoPrev model, Referral to the nearest responsible health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
HIV Infection
Connect to Protect Partnerships for Youth Prevention Interventions: Phase II
This is Phase II of a three stage project whose overall goals are to develop viable community-based HIV prevention interventions and to form and maintain the necessary community collaborations to support such Adolescent Trials…
- Trial name
- NCT00103896
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 16,706 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Condomless Sex, Human Immunodeficiency Virus (HIV)
Cape Town Young Women's Health CoOp
This two-arm cluster randomized trial tested a gender-focused comprehensive HIV testing and counselling (HTC) program, the Young Women's Health CoOp (YWHC) with a standard HTC program and targeted female adolescents (aged 16-19)…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infections (STIs), Alcohol and Drug Use
- Trial name
- NCT02974998
- Testing
- Young Women's Health CoOp (YWHC), Standard HTC
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Teen Pregnancy, Contraception Behavior
Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters
The goal of this randomized control trial (RCT) is to assess an innovative adolescent pregnancy prevention program among youth that are at the highest risk of adolescent pregnancy, to prevent pregnancy and Sexually Transmitted…
- Conditions
- Teen Pregnancy, Contraception Behavior, Sexually Transmitted Diseases, Reproductive Health
- Trial name
- NCT05889689
- Testing
- Relationship Smarts Plus & Mind Matters, Relationship Smarts Plus alone, Preparing Adolescents for Young Adulthood (PAYA).
- Where
- United States
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Trinity Church Inc.
HIV Infections
Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus)
The purpose of this study is long-term evaluation of long-acting injectable cabotegravir (CAB LA) for HIV pre-exposure prophylaxis (PrEP) in eligible participants who have completed DAIDS (Division of AIDS) sponsored studies HPTN…
- Trial name
- PALISADE (NCT06134362)
- Testing
- CAB LA
- Where
- 33 sites in Argentina, Botswana and 10 more
- Volunteers
- 2,996 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV Infections, Sexually Transmitted Infection
User-friendly HIV Testing and Counseling Services
Multicenter cohort study of individuals reporting behavioral risks of HIV acquisition, recruited among those presenting for testing for HIV and other sexually transmitted infections.
- Conditions
- HIV Infections, Sexually Transmitted Infection, Hepatitis B, Chronic, Hepatitis C
- Trial name
- NCT04585165
- Where
- 6 sites in Thailand
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
Hepatitis C Virus, HIV Infections
Trends in Risk Factors for Mother-to-Child Transmission of Hepatitis C Among a Southern European Population
According to the centres taking part in the ALHICE survey, the number of HIV-HCV co-infected women is currently decreasing. This drop was first noted in 2006 and persisted in 2007.
- Conditions
- Hepatitis C Virus, HIV Infections, Pregnancy
- Trial name
- EPIALHICE B (NCT00894257)
- Where
- 3 sites in France
- Volunteers
- 142 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
HIV/AIDS
Adapting and Evaluating an EBI to Prevent HIV/AIDS Risk Among Apache Youth
The investigators seek to adapt, implement and evaluate a randomized controlled trial of an evidence based intervention delivered by Apache interventionists to reduce HIV/AIDS risk, targeting Apache adolescents.
- Trial name
- NCT01910714
- Testing
- Focus On Youth, Health Education Control Condition
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV, Sexual Risk
Young Women's CoOp Study
The purpose of this study is to test the efficacy of a cultural-, age- and gender-focused Human Immunodeficiency Virus (HIV) prevention intervention in reducing risk behaviors among African-American young women relative to…
- Conditions
- HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse
- Trial name
- YWC (NCT01224184)
- Testing
- Young Women's CoOp, Staying Healthy and Eating Well
- Where
- 2 sites in United States
- Volunteers
- 237 people
- Sponsor
- RTI International
HIV, Sexually Transmitted Diseases
LYNX: A Novel Mobile App to Support Linkage to HIV/STI Testing PrEP for Young Men Who Have Sex With Men
This study is testing the acceptability and feasibility of a highly interactive mobile application (app) to promote HIV/sexually transmitted infection (STI) testing and uptake of pre-exposure prophylaxis (PrEP) among young men…
- Conditions
- HIV, Sexually Transmitted Diseases, Risk Reduction, Pre-Exposure Prophylaxis
- Trial name
- NCT03177512
- Testing
- LYNX Mobile App
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
HIV Infections, Candidiasis, Oral
Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups
OBJECTIVES: I. Evaluate the development of oral manifestations of human immunodeficiency virus infection in relationship to the onset of immunologic alterations and systemic symptoms in different risk groups: gay/bisexual men…
- Trial name
- NCT00004781
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy
CHOICES-TEEN Randomized Controlled Trial
This randomized controlled trial will: 1) Test the efficacy of the CHOICES-TEEN (CT) intervention compared with an Attentional Control (AC) condition on reducing the risk of substance-exposed pregnancy (SEP) and HIV/STI among…
- Conditions
- Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy, Risk for Substance-Exposed Pregnancy, HIV Risk
- Trial name
- NCT05368571
- Testing
- CHOICES-TEEN, Health and Life Skills Education
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Danielle Parrish