Clinical trials: Siblings
Childhood Cancer, Siblings
Siblings to a Child With Cancer: Needs and Pre-loss Grief
Background and Aim: Siblings to a brother or sister with cancer have reported difficulties dealing with such things as their parents' suffering, loneliness in relation to their own feelings as well as uncertainty regarding their…
- Conditions
- Childhood Cancer, Siblings, Psychosocial Functioning
- Trial name
- NCT06854822
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Ersta Sköndal University College
Children With Medical Complexity (CMC), Siblings
Sibling Caregiver CMC Pilot Study
Children with medical complexity require intense caregiving from their parents and other health care providers, such as family doctors and medical specialists.
- Conditions
- Children With Medical Complexity (CMC), Siblings, Mental Health
- Trial name
- NCT07756502
- Testing
- Mental health assessment and diagnosis, psychotherapy, and treatment
- Volunteers
- 63 people
- Sponsor
- The Hospital for Sick Children
Autism Sibling
Sibwatch: Optimizing Intervention Options for Infants and Toddler Siblings of Autistic Children
This rigorous randomized controlled trial will evaluate the efficacy and acceptability of a preemptive, telehealth intervention (tele-ImPACT) in a large, representative sample of infant siblings of autistic children, who are…
- Trial name
- Sibwatch (NCT07069413)
- Testing
- tele-ImPACT
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of Texas at Austin
Autism Sibling, Autism Spectrum Disorder
Milieu Teaching-AV (MT-AV Pilot)
This project will look at whether a novel approach to language intervention that encourages looking to audiovisual speech cues for infants with autistic older siblings (Baby Sibs), who are highly likely be diagnosed with autism…
- Trial name
- MT-AV Pilot (NCT06794476)
- Testing
- Milieu Teaching-AV
- Where
- United States
- Sponsor
- Father Flanagan's Boys' Home
Autism Sibling
Optimizing Intervention Options for Toddlers With Early Social Communication Delays
Improving social communication outcomes for toddler siblings of children with autism, who are at high risk for multiple language and communication deficits beyond autism, has important public health implications.
- Trial name
- SibWatch (NCT05307094)
- Testing
- Improving Parents as Communication Teachers
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Promotion of Positive Sibling Relationships
Innovative Family Prevention With Latino Siblings in Disadvantaged Settings
The current study is a randomized intervention trial that tests the efficacy of a family-focused sibling relationship promotion program.
- Trial name
- SIBS (NCT03706014)
- Testing
- SIBS Program, Control
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Harvard University
Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay
Effects of a Short-term Parent Mediated Social Training on Developmental Trajectories in Infants
This study is being done to examine the feasibility and impact of the Infant Achievements caregiver coaching treatment on caregiver child-engagement strategies used during play with their infant.
- Conditions
- Younger Sibling of Child With Autism Spectrum Disorder, Signs of Developmental Delay, Signs of Communication Delay, Signs of Social Delay
- Trial name
- IA (NCT03404505)
- Testing
- Infant Achievements, Caregiver Education (CE)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Retinoblastoma, Cancer Survivor
Studying Health Outcomes After Treatment in Patients With Retinoblastoma
This trial studies health outcomes after treatment in patients with retinoblastoma. Gathering health information over time from patients and family members through vision assessments, samples of tissue and saliva, and…
- Conditions
- Retinoblastoma, Cancer Survivor, Biological Sibling, Intraocular Retinoblastoma
- Trial name
- RIVERBOAT (NCT03932786)
- Testing
- Biospecimen collection, Vision assessment, Questionnaire administration
- Where
- 11 sites in United States, Canada
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Siblings of Children With Chronic Illness
SIBS-Intervention for Siblings and Parents of Children With Chronic Illness
SIBS-RCT is a randomized controlled trial comparing the effect of a 5-session group intervention for siblings and parents of children with chronic illness to 12-week waitlist.
- Trial name
- SIBS-RCT (NCT04056884)
- Testing
- SIBS intervention
- Where
- Norway
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Cystic Fibrosis in Children, Siblings
Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, Resource Program: How Does it Work?
The goal of the clinical trial is to test whether a mental health program that is delivered through the Internet works well for children and adolescents with cystic fibrosis (CF) and their healthy siblings.
- Conditions
- Cystic Fibrosis in Children, Siblings, Mental Health, Internet-based Intervention
- Trial name
- iCF-PWR (NCT06020274)
- Testing
- Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, and Resource (iCF-PWR) program
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Regina
Cystic Fibrosis, Siblings
The Development and Evaluation of iCF-PWR for Healthy Siblings of Individuals With Cystic Fibrosis
The goal of the clinical trial is to test whether a mental health program that is delivered through the Internet works well for healthy children and adolescents with siblings with cystic fibrosis (CF).
- Conditions
- Cystic Fibrosis, Siblings, Mental Health, Internet-based Intervention
- Trial name
- NCT06012084
- Testing
- Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, and Resource (iCF-PWR) program
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Regina
Autism Spectrum Disorder, Siblings
Screening for Neurodevelopmental Disorders in Siblings of Children With Autism Diagnosed in Tertiary Centers
In this study, a selective and multi-stages screening for neurodevelopmental disorders (NDD) in siblings of children with a confirmed ASD is done.
- Conditions
- Autism Spectrum Disorder, Siblings, Neurodevelopmental Disorders
- Trial name
- FRATSA (NCT05512637)
- Testing
- Step 1 - Screening ; Step 2 - Clinical interview
- Where
- France
- Volunteers
- 384 people
- Sponsor
- University Hospital, Montpellier
Siblings, Childhood Cancer
SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer
This study aims to address barriers to psychosocial care for siblings of children with cancer by piloting a group-based telehealth program for adolescent siblings of youth with cancer.
- Conditions
- Siblings, Childhood Cancer, Pediatric Cancer, Posttraumatic Stress Disorder
- Trial name
- R03 CA259898 (NCT04889755)
- Testing
- SibACCESS
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Family Relationship, Sibling Relations
A Behavioral Intervention With Foster Families
The purpose of this study is to investigate a behavioral intervention with foster families.
- Conditions
- Family Relationship, Sibling Relations, Behavior, Social
- Trial name
- NCT05405972
- Testing
- The Connected Family Series - For Foster Families
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Disability, Intellectual, Disability Psychological
The Role of Family and Individual Factors in Going Through Adolescence - Perspective of a Healthy Child.
The goal of this observational study is to investigate the specificity of the growing up process in young people with disabled siblings.
- Conditions
- Disability, Intellectual, Disability Psychological, Disability, Developmental, Diabetes
- Trial name
- NCT06156124
- Testing
- Psychological tests and psychosocial questionnaires
- Where
- Poland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Advanced MDS Without Identical Sibling Donor
Haplo-identical/Mismatched Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome
Allogeneic hematopoietic stem cell transplantation (HSCT) is currently the only curative treatment for myelodysplastic syndrome (MDS), especially for advanced MDS (blast >5%).
- Trial name
- NCT01793675
- Testing
- transplant with haploidentical donor
- Where
- 8 sites in China
- Volunteers
- 116 people
- Sponsor
- Peking University People's Hospital
Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure
Long Term Minor Sibling Donor Well-Being
The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member. Primary Aims: 1.
- Conditions
- Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure, Disturbance of Emotions Specific to Childhood and Adolescence, Transmission, Blood, Recipient/Donor
- Trial name
- NCT00667784
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center