Clinical trials: Signs and Symptoms, Digestive
Pediatric Recurrent Headache & Abdominal Pain
Family Help Program: Pediatric Recurrent Headache and Abdominal Pain
The purpose of the Strongest Families (formerly Family Help Program)is to evaluate the effectiveness of the Strongest Families distance intervention compared to usual or standard care that is typically provided to children with…
- Trial name
- NCT00267618
- Testing
- FHP Pain
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Alpha-1-antitrypsin Deficiency
Czech AATD Registry
Alpha-1-antitrypsin deficiency is the most common congenital disease of the respiratory system, leading to early pulmonary emphysema or bronchiectasis. Pulmonary involvement significantly accelerates active cigarette smoking.
- Trial name
- NCT05178277
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Thomayer University Hospital
Constipation
Biofeedback Treatment for Functional Constipation
The purpose of this randomized, controlled trial is to examine how well biofeedback treatment works to improve constipation. The study is comparing two kinds of biofeedback treatment: 1) anorectal-specific biofeedback therapy and…
- Trial name
- NCT00502957
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Crohn's Disease, Genetic Predisposition
Abnormal Fecal Microbiota in Healthy Subjects at High Risk for Crohn's Disease
Transversal multicentric French study on the microbiota in patients with Crohn's disease and their first degree healthy relatives The primary objective is the comparison of microbiota between patients with CD, healthy controls…
- Trial name
- MAGIC (NCT02826330)
- Testing
- biomarkers
- Where
- 10 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Cholangitis, Secondary Biliary, Treatment Compliance
Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy
Application of multi-center, prospective study on the severity of postoperative cholangitis biliary atresia classification, according to the degree of cholangitis targeted therapy, to improve the therapeutic effect of…
- Conditions
- Cholangitis, Secondary Biliary, Treatment Compliance, Antibodies Drug Specific
- Trial name
- NCT04370145
- Testing
- Sulperazon, Teicoplanin, Meropenem Injection
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
Nausea and Vomiting, Postoperative
The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain
The hypothesis being tested in this study is that perioperative oral administration of dexamethasone, when compared to intravenous (IV) administration, offers a similar reduction in postoperative nausea and vomiting (PONV), and…
- Trial name
- NCT04563494
- Testing
- dexamethasone
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Colorado, Denver
Constipation, Peritoneal Dialysis Complication
Peritoneal Dialysis Pilot Study: Evaluating Polyethylene Glycol (PEG) for Constipation
Constipation is a common condition, which occurs one in four Canadians. Maintaining regular bowel movements is imperative because constipation can affect the quality of PD dialysate flow and result in an unwanted effect on the…
- Trial name
- NCT03148002
- Testing
- Current Bowel Protocol (senna/lactulose), PEG Bowel Protocol (PEG/lactulose)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Nova Scotia Health Authority
Diarrhea, Drug/Agent Toxicity by Tissue/Organ
N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma
RATIONALE: Drugs used in chemotherapy, such as irinotecan and temozolomide, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Diarrhea, Drug/Agent Toxicity by Tissue/Organ, Neuroblastoma
- Trial name
- NCT00093353
- Testing
- cefixime, irinotecan hydrochloride, temozolomide
- Where
- 13 sites in United States
- Volunteers
- 30 people
- Sponsor
- New Approaches to Neuroblastoma Therapy Consortium
Pancreatic Cancer Pain
EUS Guided Celiac Neurolysis
Hypothesis: Direct CGN enhances neurolytic drug delivery into celiac ganglia and increases the efficacy of neurolysis and subsequent pain control and survival in patients with pancreatic carcinoma.
- Trial name
- NCT01615653
- Testing
- EUS
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Mayo Clinic
Eating Disorders, Female Athlete Triad
Efficacy of the Female Athlete Body Project (FAB)
Given the cost of treating eating disorders and the substantial morbidity and mortality associated with these disorders, prevention of eating disorders has considerable public health significance.
- Trial name
- FAB (NCT01735994)
- Testing
- Healthy Weight, Brochure
- Where
- United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hepatitis C
An Observational Study of Maviret (Glecaprevir/Pibrentasvir) for Korean Chronic Hepatitis C Genotypes 1 to 6 Patients According to the Standard for Re-examination of New Drugs
Post-marketing surveillance study to evaluate the real world safety and effectiveness of Maviret (Glecaprevir/Pibrentasvir) administered under a normal, routine treatment practice by Korean patients with Chronic Hepatitis C…
- Trial name
- Maviret PMS (NCT03740230)
- Where
- 61 sites in South Korea
- Volunteers
- 3,134 people
- Sponsor
- AbbVie
Eating Disorders
Comparing the Effectiveness of Two Therapies to Treat Signs of Anorexia Nervosa in Adolescents
This study will compare the effectiveness of two therapies to treat early signs of anorexia nervosa in adolescents.
- Trial name
- NCT00418977
- Testing
- Family-Based Therapy ("Maudsley Method"), Individual Supportive Psychotherapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Crohn Disease
Therapeutic Optimization Study Based on MR Enterocolonography in Patients With Crohn's Disease
This randomized, controlled study aims to evaluate the impact of therapeutic intervention (step up) for the patients who are clinical remission with Magnetic Resonance Enterocolonography (MREC) active.
- Trial name
- NCT02332356
- Testing
- azathioprine or adalimumab and infliximab
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Tokyo Medical and Dental University
Colorectal Cancer
Association of Colorectal Cancer With Nutrition, Diet, Obesity, Diabetes Mellitus, and Genetic Alterations in Taiwan
We will explore the genetic (including APC, k-ras, p53, MSI, etc.) and environmental (including family history, life style, diet, nutritional status, DM, serum IGF-I, IGFBP-3, etc.) risk factors of colorectal tumorigenesis.
- Trial name
- NCT00172757
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Short Bowel Syndrome
Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients
This study will determine if air-displacement plethysmography (ADP) provides accurate measurement of body composition (percent body fat and fat-free mass) in pediatric patients with intestinal failure, as compared to body…
- Trial name
- NCT02561819
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Christopher Duggan
Eating Disorder NOS
ASSESSMENT OF ORAL HEALTH AND ORAL HEALTH-RELATED QUALITY OF LIFE IN PATIENTS AGED 12-18 YEARS WITH EATING DISORDERS
Although numerous instruments are available to assess oral health-related quality of life (OHRQoL) in adults, there is a paucity of studies evaluating the impact of oral health on quality of life in children and adolescents.
- Trial name
- NCT07896707
- Testing
- general oral health interventions and scales
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gastroparesis
Needs Assessment Evaluating Quality of Life Issues for Gastroparesis Patients and Caregivers
The project will involve conducting a Needs Assessment for Gastroparesis patients and their caregivers with the goal of identifying quality of life issues associated with this disease.
- Trial name
- NCT01329211
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Florida
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Constipation
Ultrafast MRI Imaging to Exclude Constipation
In haematological malignancy and in immunocompromised patients, constipation is a common symptom caused by a number of factors during treatment.
- Trial name
- FIESTA (NCT02658201)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Cirrhosis, Varices, Esophageal
Probiotics for Portal Hypertension
Chronic peripheral and splanchnic vasodilatation are the hallmark hemodynamic abnormality in cirrhosis and contribute to the pathogenesis of portal hypertension.
- Trial name
- NCT01134692
- Testing
- Propranolol, Norfloxacin, VSL#3
- Where
- India
- Sponsor
- Govind Ballabh Pant Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.