Clinical trials: Sinus Surgery
Pilonidal Sinus, Pilonidal Disease
Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone)
The goal of this randomized clinical trial is to establish the efficacy of 'pit picking with laser therapy' versus 'pit picking alone' on both short and long-term outcomes in patients of 12 years and older with primary pilonidal…
- Conditions
- Pilonidal Sinus, Pilonidal Disease, Pilonidal Sinus of Natal Cleft, Pilonidal Disease of Natal Cleft
- Trial name
- LA POPA (NCT06140199)
- Testing
- Pit-picking surgery, Pit-picking surgery with Sinus Laser assisted Closure
- Volunteers
- 482 people
- Sponsor
- dr. IJM Han-Geurts
Fistula Vagina, Fistula;Rectal
Rectovaginal Fistula Repair
This study is a prospective evaluation of quality-of-life after rectovaginal fistula repair at our institution
- Trial name
- NCT05006586
- Where
- Sweden
- Volunteers
- 55 people
- Sponsor
- Uppsala University
Cushing Syndrome
Modified Desmopressin (mDesmo) Using Cold-Kit for PET/CT
The incidence of Cushing syndrome (CS) is 1.2-3.2 cases per million per year, of which adrenocorticotropic Hormone (ACTH)-dependent disease comprises approximately 70-80% of cases.
- Trial name
- Ga-68 mDesmo (NCT06962202)
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pilonidal Sinus
The Most Frequently Preferred Surgical Method In The Treatment Of Sacrococcygeal Pilonidal Disease
There is no consensus on which procedure is the ideal surgical method in the treatment of sacrococcygeal pilonidal disease (SPD).
- Trial name
- NCT04599517
- Where
- Turkey (Türkiye)
- Volunteers
- 6,748 people
- Sponsor
- Konya Meram State Hospital
Chronic Rhinosinusitis With Nasal Polyps
Efficacy of Long-Term Low Dose Macrolide Therapy in Preventing Early Recurrence of Nasal Polyps After Endoscopic Sinus Surgery
This randomized controlled trial evaluated the effectiveness of long-term, low-dose clarithromycin (250 mg/day) in reducing symptoms, improving endoscopic and radiologic scores, and preventing early recurrence of nasal polyps…
- Trial name
- NCT07316959
- Testing
- clarithromycin 250 mg
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fatima Jinnah Medical University
Vaginal Fistula, Vesico Vaginal Fistula
Feasibility of the Menstrual Cup for VVF
This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana.
- Conditions
- Vaginal Fistula, Vesico Vaginal Fistula, Obstetric; Injury
- Trial name
- FMCVVF (NCT03414060)
- Testing
- Menstrual Cup
- Where
- Ghana
- Volunteers
- 11 people
- Sponsor
- University of Ghana Medical School
Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia
Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study
Esophageal atresia (EA) is one of the most common gastrointestinal congenital anomalies that affects 1 in 2500 to 1 in 4000 live births.
- Conditions
- Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia, Esophageal Strictures
- Trial name
- BITES (NCT07100379)
- Testing
- Endoscopic Balloon Dilation
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Hypospadias
The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery.
Post-operative tissue oedema is one of the main causes of failure of hypospadias repair. Severe oedema may disrupt the suture line, invite infection and result in repair failure.
- Trial name
- NCT04196400
- Testing
- steroid betamethasone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Rhinosinusitis (Diagnosis)
Adrenaline Solution Irrigation and Bleeding During Sinus Surgery
Intranasal irrigation with normal saline is routinely used in sinus surgery to clean the tip of the nasal endoscope and clear the surgical field from blood.
- Trial name
- NCT04551703
- Testing
- Adrenaline saline irrigation
- Volunteers
- 60 people
- Sponsor
- Jordan University of Science and Technology
Spinal Cord Vascular Diseases
Surgical Intervention of Spinal Arteriovenous Malformations and Fistulas
Spinal arteriovenous fistulas (AVFs) and arteriovenous malformations (AVMs) are complex neurosurgical lesions that are very challenging to manage.
- Trial name
- SUIT-SAVM (NCT03024749)
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Hongqi Zhang, MD
Pilonidal Sinus, Surgical Wound
Ghnnam Excision Technique for Pilonidal Sinus
Pilonidal disease is a common disorder of the sacrococcygeal region. It comprises a variety of problems, including infection/abscess and the development of a chronic sinus cavity.here we try a minimmally invasive method for…
- Conditions
- Pilonidal Sinus, Surgical Wound, Dressing by Cyanoacrylate
- Trial name
- NCT01399320
- Testing
- cyanoacrylate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Coronary Artery Disease, Atheromatosis
Prognostic Indices of Atheromatosis Severity and Coronary Artery Bypass Surgery Outcomes for Patients With Coronary Artery Disease
Coronary artery disease is a multifactorial disease. Traditional risk factors, such as obesity, diabetes, hypertension, stimulate the onset of an inflammatory process in the prone vessel and perivascular adipose tissue, which has…
- Trial name
- NCT06242171
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Onassis Cardiac Surgery Centre
Crohn Disease
Comparison of Quality of Life With or Without Automatic Seton Placement in Perianal Crohn's Fistula
In patients with Crohn's disease, anal fistulas are usually treated in three stages: 1) close examination of the fistula and drainage with a seton, 2) pharmacological treatment of the inflammatory component, and 3) closure of the…
- Trial name
- SOPA (NCT05330416)
- Testing
- Group Reference Strategy, Group Test Strategy
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Acquired Adult Flatfoot Deformity, Flat Foot
Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity
Background: Adult acquired flatfoot deformity (AAFD) is a deformity of the foot which leads to pain and an altered gait pattern. There are several different surgical interventions available for treatment of AAFD.
- Conditions
- Acquired Adult Flatfoot Deformity, Flat Foot, Flexible Flatfoot
- Trial name
- NCT06211504
- Testing
- ProStop, sinus tarsi implant (STI), Conventional surgery
- Where
- 10 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Region Skane
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital
Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula
Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery
The study is primarily a descriptive study examining the physiological, ventilatory, surgical, and recovery effects of patients ≤ 6 months of age who undergo thoracoscopic surgery and to determine the accuracy of transcutaneous…
- Conditions
- Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula, Esophageal Atresia
- Trial name
- NCT02033772
- Testing
- Thoracoscopic surgery
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Arlyne Thung
Fibrolipoma of Filum Terminale, Lipomyelomeningocele
Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence
Purpose of study : to determine the preventive effect of acetazolamide administration, prone positioning, and the combination of both following the neurosurgical interventions in lumbosacral region for cerebrospinal fluid (CSF)…
- Conditions
- Fibrolipoma of Filum Terminale, Lipomyelomeningocele, Split Cord Malformation, Dermal Sinus
- Trial name
- NCT01867268
- Testing
- Acetazolamide, prone positioning, Acetazolamide+ prone positioning
- Where
- Iran
- Volunteers
- 144 people
- Sponsor
- Tehran University of Medical Sciences
Jaw, Edentulous, Jaw, Partially Edentulous
Prospective Registry of Immediate/Delayed Loading of Implants in the Cranial Bone-grafted Severely Atrophic Jaw
Edentulism is often associated with a negative psychosocial impact. The concept of prosthetic rehabilitation in which a prosthesis is supported by osseointegrated implants, was first introduced in the late 1960s by Brånemark et…
- Trial name
- ILICRAN (NCT02664298)
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Sint-Jan AV
Gastroschisis, Congenital Diaphragmatic Hernia
An Exploratory Physiological Study of Post-operative Recovery in Surgical Neonates and Dimethylarginine:Arginine Levels
The SuNDiAL study will measure levels of two naturally occurring amino acids: Arginine and Asymmetric Dimethylarginine (ADMA) in neonates undergoing abdominal surgery in the first 5 days of life due to congenital abdominal…
- Conditions
- Gastroschisis, Congenital Diaphragmatic Hernia, Duodenal Atresia, Oesophageal Atresia With Tracheo-Oesophageal Fistula
- Trial name
- SuNDiAL (NCT06731855)
- Testing
- Abdominal Surgery for congenital gut malformation in the first 5 days of life.
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Liverpool Women's NHS Foundation Trust
Hypospadias, Hypospadias, Coronal
Caudal Anesthesia Versus Local Anesthesia in Hypospadias
Hypospadias is among the most common congenital genital malformations in boys and is typically treated through surgical intervention.
- Conditions
- Hypospadias, Hypospadias, Coronal, Caudal Anesthesia, Children
- Trial name
- NCT06417060
- Testing
- Caudal block anesthesia, Dorsal penile block anesthesia
- Where
- 3 sites in North Macedonia, Russia and 1 more
- Volunteers
- 200 people
- Sponsor
- Necmi Kadıoğlu Hospital