Clinical trials: Skin Condition
Fabry's Disease
Analysis of the Nervous System in Patients With Fabry's Disease
Fabry's disease a genetic disorder (X-linked recessive) due to the absence of the enzyme ceramidetrihexosidase. The disease is characterized by abnormal collections of glycolipids in cells (histiocytes) within blood vessel walls…
- Trial name
- NCT00001491
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Breast Cancer
Cancer Of the BReast Asanas Study (COBRA)
Rationale: Women with hormone-receptor positive breast cancer are usually prescribed endocrine therapy for a period of 5-10 years. This treatment reduces the risk of recurrence and improves overall survival in these women.
- Trial name
- COBRA (NCT06480513)
- Testing
- live yoga, live remote yoga
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- UMC Utrecht
Epidermolysis Bullosa
Topical BPM31510 3.0% Cream in Patients With Epidermolysis Bullosa
This is a single-center study to investigate the effects of a topical cream on patients 12 years of age and older that have been diagnosed with epidermolysis bullosa.
- Trial name
- NCT02793960
- Testing
- topical BPM31510 3.0% Cream
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Shasa Hu
Atopic Dermatitis
Adjunctive Oral Iron Supplementation in Atopic Dermatitis
The present randomized controlled trial aims to evaluate the effect of adjunctive oral iron supplementation on disease severity and quality of life in adolescents with mild to moderate atopic dermatitis.
- Trial name
- NCT07613190
- Testing
- Oral iron
- Volunteers
- 124 people
- Sponsor
- Cairo University
Breast Cancer
Role of FGF21 in Breast Cancer
The present study aims to evaluate the serum level of FGF-21 in patients with breast cancer and its correlation with clinical, laboratory, and pathological data.
- Trial name
- NCT07113418
- Testing
- ELISA
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Condylomata Acuminata
Efficacy of Intralesional MMR Vaccine,Intralesional Candidal Antigen&Topical Podophyllin in Treatment of Genital Warts
This study compares the safety and efficacy of intralesional Candidal antigen versus Intralesional MMR vaccine versus podophyllin for treatment of genital warts.
- Trial name
- NCT03853785
- Testing
- MMR vaccine, Candida antigen, Topical Podophyllin
- Volunteers
- 45 people
- Sponsor
- Assiut University
Crohn Disease, Ulcerative Colitis
Expanded Access to Upadacitinib
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to upadacitinib prior to approval by the local regulatory agency. Availability will depend on territory eligibility.
- Conditions
- Crohn Disease, Ulcerative Colitis, Idiopathic Arthritis (Including sJIA, pJIA, or JPsA), Atopic Dermatitis
- Trial name
- NCT04159597
- Testing
- Upadacitinib
- Sponsor
- AbbVie
Acne Vulgaris
Non-cutting Laser Therapy in the Treatment of Acne
The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin.
- Trial name
- NCT00113425
- Testing
- V-Beam laser, Candela Corp., 595 nm wavelength
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Scabies
Comparison of the Efficacy and Safety of Ivermectin to Permethrin
Comparison of the efficacy and safety of a single administration of ivermectin to a single administration of permethrin for the treatment of scabies
- Trial name
- NCT00262418
- Testing
- Administration of ivermectin or permethrin
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- University Ghent
Head and Neck Cancer, Non-melanomatous Skin Cancer
Radiation Therapy in Treating Patients With Head and Neck Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which regimen of radiation therapy is more effective for head and neck cancer.
- Trial name
- NCT00021125
- Testing
- adjuvant therapy, radiation therapy
- Where
- United Kingdom
- Volunteers
- 460 people
- Sponsor
- Medical Research Council
Skin Ulcer, Photodynamic Therapy
Low Concentration ALA-PDT in Treatment of Skin Ulcer
Skin ulcer is a common disease with complicated etiopathogenes, which makes it hard to be cured. It has been reported that photodynamic therapy (PDT) can be used to treat skin ulcers which were caused by different diseases.
- Trial name
- NCT04689243
- Testing
- ALA-PDT, red light
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Sichuan Provincial People's Hospital
Juvenile Idiopathic Arthritis
Withdrawal of Etanercept After Successful Treatment of Juvenile Idiopathic Arthritis
The purpose of this study is to determine whether etanercept can be withdrawn successfully (i.e. no occurrence of flares) in juvenile idiopathic arthritis (JIA) patients in whom disease remission is reached. Goals: 1.
- Trial name
- ABC-STOP (NCT01287715)
- Testing
- etanercept
- Where
- 10 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasmus Medical Center
Penile Skin, Buccal Mucosal Graft
Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture
The aim of this study is to analyze the outcomes of dorsal onlay buccal mucosal graft (BMG) and penile skin graft (PSG) urethroplasty in the management of long segment bulbar urethral stricture.
- Conditions
- Penile Skin, Buccal Mucosal Graft, Augmentation, Urethroplasty
- Trial name
- NCT07074717
- Testing
- Buccal Mucosal Graft (BMG) Urethroplasty, Penile Skin Graft (PSG) Urethroplasty
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Atopic Dermatitis
Clobetasol Topical Oil for Children With Moderate to Severe Atopic Dermatitis
Open-Label Study designed to evaluate the HPA axis suppression potential of Clobetasol Topical Oil and pharmacokinetic safety / systemic exposure to clobetasol when Clobetasol Topical Oil is applied to pediatric subjects with…
- Trial name
- NCT03847389
- Testing
- Clobetasol propionate 0.05% Topical Oil
- Where
- 6 sites in United States
- Volunteers
- 8 people
- Sponsor
- Hill Dermaceuticals, Inc.
Hereditary Angioedema (HAE)
Efficacy Study of DX-88 (Ecallantide) to Treat Acute Attacks of Hereditary Angioedema (HAE)
The purpose of this study is to evaluate the efficacy and safety of DX-88 (ecallantide) versus placebo in the treatment of moderate to severe acute attacks of hereditary angioedema.
- Trial name
- NCT00457015
- Testing
- ecallantide, Phosphate Buffer Saline (PBS), pH 7.0
- Where
- 45 sites in United States, Canada and 1 more
- Volunteers
- 96 people
- Sponsor
- Shire
Melanoma
An Investigational Immuno-therapy Study of Nivolumab Combined With Ipilimumab Compared to Nivolumab by Itself After Complete Surgical Removal of Stage IIIb/c/d or Stage IV Melanoma
The purpose of this study is to determine whether an investigational immunotherapy Nivolumab, when combined with Ipilimumab, is more effective than Nivolumab by itself, in delaying the return of cancer in patients who have had a…
- Trial name
- CheckMate 915 (NCT03068455)
- Testing
- nivolumab, ipilimumab
- Where
- 124 sites in United States, Australia and 17 more
- Volunteers
- 1,844 people
- Sponsor
- Bristol-Myers Squibb
Potentially Malignant Lesions, Oral Lichen Planus
Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions
The aim of this study is to evaluate salivary expression of lncRNA DQ786243 as a potential marker for diagnosis of oral potentially malignant lesions compared to normal controls and its effect on salivary expression of miRNA146a.
- Conditions
- Potentially Malignant Lesions, Oral Lichen Planus, Leukoplakia, Oral
- Trial name
- NCT05730855
- Testing
- Real-time Polymerase Chain Reaction technique
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Acne Vulgaris
Study of Two Different 10.0% Benzoyl Peroxide Creams for Mild to Moderate Acne Vulgaris
This study is a split face, paired-comparison, pilot study of 10 subjects. Participants in this study will be patients seen at Children's Memorial Hospital, who are clinically diagnosed with mild to moderate acne vulgaris.
- Trial name
- NCT00787943
- Testing
- Topical benzoyl peroxide 10.0% cream - Formulation 1, Topical benzoyl peroxide 10.0% cream - Formulation 2
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Identification of Jaundice in Newborns Using Smartphones
Neonatal jaundice is a common and most often harmless condition. However, when unrecognized it can be fatal or cause serious brain injury. Three quarters of these deaths are estimated to occur in the poorest regions of the world.
- Trial name
- NCT04182555
- Testing
- Bilirubin estimates from Smartphone Application, Bilirubin concentration measured in standard blood samples, Bilirubin estimates from standard transcutaneous device
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Breast Cancer
Mutation of BRCA1/2 and Other Potential Genes in Triple-negative Breast Cancer
The study is to determine the prevalence of potential chemo-response related genes mutation in TNBC patients between pCR and SD/PD group, which achieved after NAC; and to evaluate potential relationship between these gene…
- Trial name
- NCT02670668
- Testing
- Mutation analysis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.