Clinical trials: Skin Condition
Molluscum Contagiosum
Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum, Phase 2
Cantharidin is cited in the dermatology and pediatric literature as a valuable treatment option. Treatment is often available in private practice offices, where a prescribing physician may offer a non-FDA approved treatment on an…
- Trial name
- NCT03017846
- Testing
- Cantharidin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Steven R Cohen
Breast Cancer, Breast Neoplasms
Delphinus SoftVue™ ROC Reader Study
The purpose of this multi-reader, multi-case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in…
- Trial name
- DMT SV RRS1 (NCT03698942)
- Testing
- Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Dermatitis, Atopic
NMF-CsA-Dupi Trial
The goal of this study is to investigate whether stratification of children with atopic dermatitis on the NMF biomarkers results in an improvement of effectiveness and efficiency in the use of systemic treatment (ciclosporin and…
- Trial name
- NCT04878770
- Testing
- Topical corticosteroids, Systemic cyclosporine, Systemic dupilumab
- Where
- Netherlands
- Volunteers
- 318 people
- Sponsor
- Erasmus Medical Center
Metastatic Breast Cancer
Trial to Evaluate the Therapeutic Benefit of Fulvestrant in Combination With ZACTIMA in Postmenopausal Women With Bone Predominant, Hormone Receptor Positive Metastatic Breast Cancer
The purpose of this study is to evaluate whether the combination of fulvestrant and ZACTIMA, versus fulvestrant plus placebo, results in a significant decrease in the bone marker, urinary N-Telopeptide (NTx) in postmenopausal…
- Trial name
- ZAMBONEY (NCT00811369)
- Testing
- Fulvestrant + ZACTIMA
- Where
- 13 sites in Canada
- Volunteers
- 126 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer, Sentinel Lymph Node
Sentinel Lymph Node Biopsy in Early Breast Cancer: a Real-world Multicenter Cross-sectional Study (CABS001 Study)
Objective: To investigate the current clinical practice of sentinel lymph node biopsy (SLNB) in patients with early stage breast cancer in China.
- Trial name
- NCT04156841
- Testing
- mapping agent, neoadjuvant chemotherapy
- Where
- China
- Volunteers
- 21,000 people
- Sponsor
- Xijing Hospital
Breast Cancer
Effectiveness of Reduced GCSF Dosing in Patients With a Low to Moderate Risk of Febrile Neutropenia
The study aims to confirm that a reduced dosage of GCSF is effective in preventing febrile neutropenia among patients with breast cancer, treated with chemotherapy and presenting with a low to moderate risk of developing febrile…
- Trial name
- PAPALDO (NCT01658956)
- Testing
- GCSF administration on days 8 and 12 after chemotherapy
- Where
- Belgium
- Volunteers
- 142 people
- Sponsor
- Jules Bordet Institute
RASopathy, Costello Syndrome
Prevalence and Characterization of Pain in RASopathies
RASopathies are a group of syndromes caused by variants in genes belonging to the RAS/MAPK pathway. Pain is a neglected topic in RASopathies but it is frequently complained by affected individuals.
- Conditions
- RASopathy, Costello Syndrome, Cardio-Facio-Cutaneous Syndrome, Noonan Syndrome
- Trial name
- 3717 (NCT06355622)
- Testing
- Characterization of pain
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diaper Rash
Evaluation of the Safety and Performance of LiNiDERM® in the Prevention of Infant Diaper Rash
Result of immaturity of the skin and factors promoting maceration and mechanical interactions, Irritant diaper dermatitis (IDD) can manifest as early as the third week of life.
- Trial name
- NCT03640897
- Testing
- Liniderm, Wipes, Water
- Where
- Poland
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Laboratoires Gilbert
Blister, Wound of Skin
Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.
This is a three-part, Phase I, first-in-human study designed to evaluate the safety, tolerability, and potential systemic exposure of multiple topical doses of TCP-25.
- Conditions
- Blister, Wound of Skin, Epidermolysis Bullosa, Varicose Ulcer of Lower Limb
- Trial name
- NCT05378997
- Where
- Sweden
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Xinnate AB
Acne
An Observational Clinical Study to Evaluate the Efficacy of the CeraVe Skin Care Line
This is an observational clinical study to evaluate the efficacy of the CeraVe Skin Care product line in improving mild to severe facial acne.
- Trial name
- NCT07044024
- Testing
- CeraVe
- Volunteers
- 240 people
- Sponsor
- ChinaNorm
Estrogen Receptor-positive Breast Cancer, Progesterone Receptor Positive Tumor
Pilot Study Estradiol Followed by Exemestane Hormone Receptor + Metastatic Breast Cancer
RATIONALE: Estrogen can cause the growth of tumor cells. Hormone therapy using therapeutic estradiol may fight breast cancer by lowering the amount of estrogen the body makes.
- Conditions
- Estrogen Receptor-positive Breast Cancer, Progesterone Receptor Positive Tumor, Recurrent Breast Cancer, Stage IIIC Breast Cancer
- Trial name
- NCT01385280
- Testing
- therapeutic estradiol, exemestane, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Arizona
Acute Pain
Effectiveness of a Virtual Reality Game for Pediatric Pain and Anxiety Management During Skin Prick Testing
This study investigated the effectiveness of virtual reality (VR) distraction, compared to book distraction and no distraction, in reducing pain and anxiety during a medical procedure in a pediatric population: the skin prick…
- Trial name
- NCT05796596
- Testing
- Experimental: Virtual Reality (VR) distraction, Active Comparator: Distraction by the book
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- University of Liege
Breast Cancer
Digital Mammography Screening Trial (ACRIN6652)
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for cancer. It is not yet known which type of mammography is more effective in detecting breast cancer.
- Trial name
- DMIST (NCT00008346)
- Testing
- Full Field Digital Mammography, Screen Film Mammography
- Where
- 32 sites in United States, Canada
- Volunteers
- 49,528 people
- Sponsor
- American College of Radiology Imaging Network
Carbohydrate Ingestion
Role of Low Carbohydrate Nutrient in Healing of Infected Diabetic Foot
A low-carbohydrate diet, when combined with standard wound care and diabetes management, appears to accelerate the healing of infected diabetic foot, improve blood glucose control, reduce systemic inflammation and promoting…
- Trial name
- LCN (NCT06759688)
- Testing
- Carbohydrates restriction
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sarah Magdy Abdelmohsen
Cellulitis
Use of Corticosteroids in Children With Cellulitis
The aim of this study is to evaluate the efficacy of addition of corticosteroid therapy to antibiotic treatment during the first 48 hours of admission to the hospital in patients with cellulitis and its impact in the duration of…
- Trial name
- NCT02087527
- Testing
- Dexamethasone, Normal Saline
- Where
- Argentina
- Volunteers
- 19 people
- Sponsor
- Hospital General de Niños Pedro de Elizalde
Tinea Pedis
Clinical Equivalence of Two Butenafine Hydrochloride 1% Creams in Patients With Interdigital Tinea Pedis
To demonstrate comparable safety and efficacy of Taro Pharmaceuticals Inc. butenafine hydrochloride cream 1% (test product) and Lotrimin Ultra® cream (reference listed drug) in the treatment of interdigital tinea pedis, and to…
- Trial name
- NCT00835510
- Testing
- Butenafine cream 1% manufactured by Taro, Lotrimin Ultra (butenafine) 1%, Butenafine Vehicle manufactured by Taro
- Where
- 17 sites in United States, Belize
- Volunteers
- 548 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Breast Cancer
Study of Biomarkers in Tissue Samples From Patients With Breast Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01004796
- Testing
- cytogenetic analysis, microarray analysis, mutation analysis
- Sponsor
- University of Wisconsin, Madison
Cholesteatoma
Detection of Cholesteatoma Using Diffusion Magnetic Resonance Imaging
Cholesteatoma is a retraction pocket lined with squamous epithelium lined with keratin debris occurring within pneumatized spaces of the temporal bone.
- Trial name
- NCT03305796
- Testing
- Diffusion magnetic resonance imaging
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acne Vulgaris
A Clinical Trial Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris
The purpose of this study is to assess the effectiveness of IDP-110 in treating patients with acne vulgaris.
- Trial name
- NCT00663286
- Testing
- IDP-110, Clindamycin, Benzoyl peroxide
- Where
- 33 sites in United States
- Volunteers
- 1,399 people
- Sponsor
- Dow Pharmaceutical Sciences
Atopic Dermatitis
Study to Determine the Effect of an Anti-IgE Agent on Inflammatory Cells in the Skin of Atopic Dermatitis Patients
Elevated levels of immunoglobuline E in blood are said to promote the occurence of atopic dermatitis; in fact, many patients with atopic dermatitis have high IgE levels.
- Trial name
- NCT00822783
- Testing
- Omalizumab
- Where
- Austria
- Sponsor
- Medical University of Vienna
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