Clinical trials: Sleep Apnea, Obstructive
Obstructive Sleep Apnea Syndrome
Inflammatory Mediators in Obstructive Sleep Apnoea Syndrome; Mechanisms of Production and the Effect of Long Term Antioxidants Administration
Obstructive Sleep Apnea Syndrome (OSAS) is associated with elevated plasma levels of IL-6 and TNF-α, which cannot be accounted for by obesity (Vgontzas et al Sleep Med Rev 2005;9:211-24, Ciftci et al Cytokine 2004;28:87-91].
- Trial name
- NCT01188005
- Testing
- n-CPAP, Oxygen supplementation, Vitamin A, Vitamin C, Vitamin E, Allopurinol, N-Acetylcysteine
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Athens
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Down Syndrome: Clinical Examination Issue
Obstructive sleep apnea (OSA) is a common condition of Down syndrome patients. In pediatric practice, there is no way to determine the children with an increased risk.
- Trial name
- NCT02732431
- Testing
- Sleep Symptom
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Fondation Lenval
Obstructive Sleep Apnea, Transverse Maxillary Deficiency
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children
OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) in children is a frequent respiratory disorder, whose prevalence is estimated at between 1.2 and 5.7%, and which, if left untreated, can cause severe medical complications.
- Trial name
- ASCOT (NCT07086612)
- Testing
- over nigtht ventilatory polysomnograph test
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Obstructive Sleep Apnea Syndrome
Cytokine Profiles in Children With Obstructive Sleep Apnea
The purpose of this study is to compare the cytokine profile of tonsillar and peripheral blood mononuclear cells in patients with obstructive sleep apnea (OSA) and to compare the blood mononuclear cell cytokine secretion profile…
- Trial name
- NCT00456573
- Testing
- tonsillectomy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Obstructive Sleep Apnea (OSA)
Prevalence of Obstructive Sleep Apnoea (OSA) Among 4-8 Years Old Children in the General Population
The purpose of this study is to estimated prevalence of obstructive sleep apnea (OSA) in 4-8 year old children. To date, most studies estimating prevalence of sleep apnea in young children are based on utilizing subjective…
- Trial name
- NCT05479201
- Testing
- Home based sleep test
- Where
- Iceland
- Volunteers
- 386 people
- Sponsor
- Akureyri Hospital
Sleep Apnea, Obstructive, Craniofacial Abnormalities
3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea
The purpose of this study is to determine whether patient-specific computer-aided design (CAD) and three-dimensional (3D) printing can be utilized to produce personalized, effective continuous positive airway pressure (CPAP)…
- Conditions
- Sleep Apnea, Obstructive, Craniofacial Abnormalities, Pediatric Disorder
- Trial name
- NCT02261857
- Testing
- Personalized continuous positive airway pressure (CPAP) mask
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Glenn Green
To Compare the Difference of AHI Variation Between LSG and Combined Surgery
Effects of Combined Surgery on Obstructive Sleep Apnea in Obese Patients: an Open-label Randomized Controlled Clinical Trial
This research is created for compare the difference of AHI variation between LSG and combined surgery on obstructive sleep apnea in obese patients , evaluate the risk of combined surgery and explore the correlative factor of the…
- Trial name
- NCT03227939
- Testing
- Laparoscopic sleeve gastrectomy（LSG）, Uvulopalatopharyngoplasty(UPPP) and Adenoidectomy/Tonsillectomy
- Volunteers
- 100 people
- Sponsor
- Bing Wang
Hypoxemia, Obstructive Sleep Apnea
The Prediction Model of Hypoxemia for Safe Bronchoscopy
The purpose of this study is to develop the hypoxemia prediction model during fiberoptic bronchoscopy under MAC(monitored anesthesia care) anesthesia.
- Trial name
- NCT01370993
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Bundang Hospital
Sleep Apnea, Home Respiratory Polygraphy Sleep Study
Home Respiratory Polygraphy in Childhood Sleep Apnea-Hypopnea Syndrome (CHILDSLEEP).
The aims of the study is to assess the diagnostic utility of home respiratory polygraphy (HRP) complemented with polysomnography (PSG) in childhood Obstructive Sleep Apnea-Hypopnea Syndrome (OSAS), as well as its usefulness in…
- Conditions
- Sleep Apnea, Home Respiratory Polygraphy Sleep Study, Childhood Sleep Apnea, Polysomnography
- Trial name
- CHILDSLEEP (NCT04340310)
- Testing
- Home respiratory polygraphy
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Universitario San Juan de Alicante
Obstructive Sleep Apnea Syndrome
Management of Obstructive Sleep Apnea (OSA) in Children and Maxillary and Mandibular Development
Assessment of the association of maxillary expansion using a rapid palatal expansion, use of a mandibular advancement appliance (MGA™) and of a device allowing sleep in a semi-seated position (Yoobreath™) in patients with…
- Trial name
- SAOS (NCT03267927)
- Testing
- Rapid palatal expansion, MGA™ system, Yoobreath™ system
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Rennes University Hospital
Obstructive Sleep Apnea
Prevalence of Sleep Apnoea in Adolescents
Obstructive sleep apnoea (OSA) is associated with a variety of important complications, namely cardiovascular, neurocognitive and metabolic disturbances. The prevalence of OSA is well studied in children and adults.
- Trial name
- NCT03895775
- Where
- Hong Kong
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Can Postoperative Outcomes be Predicted From Asking OSA Screening Questions Pre-operatively?
The proposed research will determine whether a 6-item screening questionnaire previously shown to correlate with moderate or severe OSA is useful for predicting postoperative outcomes in children undergoing surgery under general…
- Trial name
- NCT02930538
- Testing
- Survey
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Obstructive Sleep Apnea
Positional Therapy for Childhood Obstructive Sleep Apnoea
Obstructive sleep apnoea (OSA) in children is a prevalent sleep disorder associated with a wide spectrum of morbidities, including neurobehavioural, cardiovascular, and metabolic complications.
- Trial name
- NCT06453018
- Testing
- Positional device, Rematee Bumper Belt or Night Shift
- Where
- Hong Kong
- Volunteers
- 5 people
- Sponsor
- Chinese University of Hong Kong
Sleep Apnea, Obstructive
Establishment of a Diagnosis and Treatment System for Information Processing Damage in Children With OSAHS
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common childhood sleep disorder with an incidence of 3% . Studies have confirmed that OSAHS can cause multiple systemic dysfunction in children, especially affecting…
- Trial name
- NCT04080089
- Testing
- Surgical treatment, drug therapy, remote cognitive training
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Sleep Apnea Syndromes, Sleep Disorder
WatchPAT Device Validation Study Compared to Polysomnography
Validation study of a novel sleep Device compared to a traditional sleep study.
- Conditions
- Sleep Apnea Syndromes, Sleep Disorder, Sleep
- Trial name
- WPAT (NCT03188718)
- Testing
- WatchPAT Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pediatric Sleep Apnea
Collaborative Care Model for Allergic Rhinitis With Obstructive Sleep Apnea From Prevention to Treatment.
In this project,the investigators aim to establish a Collaborative Care Model of TCM and Western Medicine to improve the quality of life and symptoms of AR with OSA children and educate care-givers diet and massage information to…
- Trial name
- NCT04621513
- Testing
- laser acupuncture (RJ laser S/N 1813458), western medicine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Chronic Rhinosinusitis
Validation of the Chinese Version of the Sinus and Nasal Quality of Life Survey (SN-5)
The purpose of our study was to validate the Chinese version of the Sinus and Nasal Quality of Life Survey (SN-5)and correlation with the incidence of pediatric obstructive sleep apnea and asthma.
- Trial name
- NCT04836403
- Testing
- Sinus and nasal quality of life survey questionnaire (SN-5)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Cleft Palate
Sleep and Behavior in Children With Cleft Palate
The purpose of this study is to determine whether cleft palate repair increases the risk for obstructive sleep apnea in children and whether sleep apnea could explain learning and behavior difficulties that are often observed.
- Trial name
- NCT01046591
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Michigan
OSA, Opioid
Effect of Opioids on Central Control of Ventilation in Children With Obstructive Sleep Apnea
Children OSA exhibit varying responses to opioids. It is unknown if the degree of intermittent hypoxemia results in different opioid sensitivity
- Conditions
- OSA, Opioid, Adenotonsillectomy
- Trial name
- NCT05051189
- Testing
- Fentanyl Citrate
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Baylor College of Medicine
Obstructive Sleep Apnea
Fentanyl Test and A Short OSAS Screening Scale for Severe Obstructive Sleep Apnea
The aim of this study was to estimate and compare the value of the preoperative fentanyl test and the short OSAS screening scale to diagnose severe obstructive sleep apnea；and to observe the required amount of hydromorphone and…
- Trial name
- NCT03705780
- Testing
- the short OSAS scale, fentanyl test
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University