Clinical trials: Sleep Disturbances and Insomnia
Gastroesophageal Reflux Disease, Chronic Insomnia
Effect of Rozerem on the Perception of GERD Symptoms in Patients With Chronic Insomnia.
To determine if administration of Rozerem in comparison to a placebo reduces or eliminates gastroesophageal reflux disease(GERD) symptoms in individuals with both GERD and chronic insomnia.
- Trial name
- Rozerem (NCT01128582)
- Testing
- Rozerem (ramelteon)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Southern Arizona VA Health Care System
Cerebral Palsy (CP), Pain
EFFECTS OF AROMATHERAPY AND REFLEXOLOGY ON PAIN, SLEEP, AND SATISFACTION IN CHILDREN WITH CEREBRAL PALSY
This randomized controlled trial was conducted to evaluate the effects of aromatherapy and foot reflexology on pain, sleep quality, and parental satisfaction in children with cerebral palsy.
- Conditions
- Cerebral Palsy (CP), Pain, Sleep Disorder (Disorder)
- Trial name
- AROMA-REF CP (NCT07519291)
- Testing
- Aromatherapy, Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hakkari Universitesi
Smartphone Addiction, Students, Nursing
Motivational Interview Based Intervention Program on Smartphone Addiction and Sleep Quality
Smartphones are the technological devices of our age that are constantly evolving and whose use is becoming more widespread day by day.
- Trial name
- NCT06098274
- Testing
- Motivational interviewing program based on transtheoretical model
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mustafa Yumusak
Emotional Disturbance, Emotional Regulation
AI-assisted GNW on Adolescent Emotional Distress
This cluster-randomized controlled trial aims to evaluate the efficacy of an AI-assisted Guided Narrative Writing (AI-GNW) in alleviating emotional distress among adolescents.
- Conditions
- Emotional Disturbance, Emotional Regulation, Insomnia
- Trial name
- NCT07105137
- Testing
- AI-GNW, NF-GNW, NWG
- Where
- China
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Peking University
Sleep Disturbance
Blocking Blue Light in Pregnancy, Effects on Melatonin Profile and Sleep
Sleep disturbances are common in pregnancy, and the incidence increases during the third trimester. Light and specially the blue wavelengths of light, is affecting sleep and the circadian rhythm.
- Trial name
- NCT03114072
- Testing
- Blue-blocking glasses, Light grey control glasses
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Attention-Deficit/Hyperactivity Disorder, Attention Deficit Disorder
Effect of Guanfacine Extended-Release on Attention Deficit Hyperactivity Disorder (ADHD)-Associated Insomnia
This study seeks to determine, using special sleep tests (polysomnography and actigraphy) if guanfacine extended release is able to improve nighttime sleep in children with ADHD - associated insomnia while improving daytime ADHD…
- Conditions
- Attention-Deficit/Hyperactivity Disorder, Attention Deficit Disorder, Insomnia, Sleep Disorders
- Trial name
- NCT01156051
- Testing
- Guanfacine extended-release tablets
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Children's Specialized Hospital
Insomnia, Delayed Sleep Phase
Effects of Cognitive Behavioural Therapy and Bright Light Therapy for Insomnia in Adolescents With Evening Chronotype
Insomnia is prevalent in adolescents. Together with an increase of evening preference (i.e. evening chronotype) in adolescent, sleep disturbance in adolescents are associated with a constellation of adverse outcomes.
- Trial name
- NCT04256915
- Testing
- Cognitive Behavioural Therapy for Insomnia (CBT-I) + Bright Light Therapy
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Insomnia, Anxiety
CBT-I Versus CBT-I+ACT for Youths With Insomnia and Anxiety
Insomnia in adolescents and youth is a long-standing public health concern due to its high prevalence and association with various physical and mental health problems.
- Conditions
- Insomnia, Anxiety, Youth
- Trial name
- NCT06156306
- Testing
- CBT-I, CBT-I combined ACT
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Chronic Insomnia, Transcranial Direct Current Stimulation
Clinical Efficacy and Mechanism of High Definition tDCS Based on dmPFC in the Intervention of Chronic Insomnia
To investigate the intervention effect of transcranial direct current stimulation (tDCS) on subjective and objective insomnia symptoms and daytime function of chronic insomnia patients.
- Trial name
- NCT06290492
- Testing
- transcranial direct current stimulation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- WANG KAI
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Autism Spectrum Disorders, Insomnia
Telephone Care Management to Address Sleep Problems in Young Children With Autism
The investigators will conduct a randomized controlled trial comparing a telephone based intervention (TCM) to usual care (UC). TCM will feature a registered nurse providing a series of phone calls to assist caregivers in…
- Trial name
- NCT01558180
- Testing
- Telephone Care Management, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nationwide Children's Hospital
Insomnia, Delayed Sleep Phase Disorder
Blue-blocking Glasses for Sleep Disorders in Child and Adolescent Psychiatry
Sleep problems and regulation difficulties are frequent in the child and adolescent psychiatry population. Insomnia and delayed sleep-wake phase disorders (DSPWD) are highly prevalent, and risk factors for developing more severe…
- Conditions
- Insomnia, Delayed Sleep Phase Disorder, Hyperarousal, Transdiagnostic Psychopathology
- Trial name
- BATCAT-pilot (NCT07433491)
- Testing
- Blue-blocking glasses (BB-glasses) or real darkness from 9 p.m. to desired wake-up time + night mode setting on mobile phone, Control
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Fonna
Taking Benzodiazepines for Any Reason for 3 Months, Benzodiazepine Dependence
Promoting Benzodiazepine Cessation Through an Electronically-delivered Patient Self-management Intervention
Benzodiazepines (e.g., Ativan, Xanax) are widely prescribed medications that are used mainly to treat anxiety and sleeping difficulties.
- Trial name
- EMPOWER-ED (NCT04572750)
- Testing
- EMPOWER-ED
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Sleep Initiation and Maintenance Disorders
A Study to Evaluate the Safety of DAYVIGO (Lemborexant) Tablets in Participants With Insomnia.
The purpose of the study is to evaluate the incidence of somnolence, parasomnia, narcoleptic symptoms, and suicidal ideation/suicidal behavior after administration of lemborexant (DAYVIGO) in daily practice.
- Trial name
- NCT04573556
- Testing
- Lemborexant
- Where
- 3 sites in Japan
- Volunteers
- 550 people
- Sponsor
- Eisai Co., Ltd.
Sleep Quality, Implementation
Cascading A Healthy Sleep Intervention In Vocational Education
Sleep is crucial for the mental, cognitive and physical health of adolescents. However, teenagers in 2024 sleep less and less and their sleep is of poorer quality.
- Trial name
- NCT07030556
- Testing
- Healthy Sleep Intervention, Co-creation process, Training for teachers
- Where
- Belgium
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Ghent
Insomnia
Gabapentin's Effects on Insomnia in Patients With Recent Concussion
In this open-label, pilot study the investigators will be assessing gabapentin's effects on insomnia and other concussion-related symptoms in patients with a recent concussion experiencing insomnia.
- Trial name
- NCT01421264
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- State University of New York at Buffalo
Attention Deficit Hyperactivity Disorder
Efficacy, Safety, and Tolerability of Ambien (Zolpidem) in the Treatment of Children Ages 6 to 17 With Attention Deficit Hyperactivity Disorder (ADHD)-Associated Insomnia
There has been an increased interest in the association between ADHD and sleep disorders over the past years. A high incidence of sleep disturbance, ranging from 10% to 70%, has been identified in ADHD children regardless of…
- Trial name
- Zolkids (NCT00318448)
- Testing
- Zolpidem (SL800750)
- Where
- 2 sites in United States, Canada
- Volunteers
- 201 people
- Sponsor
- Sanofi
Sleep Apnea, Obstructive, Insomnia
The IPAD Cohort Study: Insomnia and Positive Airway Pressure Adherence in Children and Adolescents
Positive Airway Pressure (PAP) is a treatment used to help people with sleep-disordered breathing, particularly those with obstructive sleep apnea (OSA).
- Trial name
- IPAD (NCT07176767)
- Testing
- Positive airway pressure therapy
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Lena Xiao
Insomnia
Comparison of the Effects of Support and Non-support Online CBT-I
Insomnia is the most prevalent sleep problem in children and adolescents and it has been found to predict the development of mental health problems in young adulthood.
- Trial name
- NCT05011929
- Testing
- Cognitive behavioral therapy
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Burnout Syndrome, Depression Disorder
The COMET Study: a Prospective COhort of MEdical residenTs to Assess Professional, Personal and Psychological Trajectories of Residents in General Internal Medicine
Introduction. Switzerland, like most Western countries, faces a paradox: an ageing, multimorbid population needs general internal medicine (GIM) physicians more than ever, yet fewer young doctors choose - and stay in - the…
- Conditions
- Burnout Syndrome, Depression Disorder, Insomnia, Perceived Stress
- Trial name
- COMET (NCT07707453)
- Where
- 3 sites in Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Fribourg