Clinical trials: Smell Disorder
Olfaction, Diet
The Effects of Acute Caloric Deprivation on Odour Identification and Food Reward
The purpose of this study is to determine how the modality of energy depletion can differently impact appetite hormones, ad libitum food intake, food hedonics, and olfaction.
- Conditions
- Olfaction, Diet, Exercise, Energy Depletion
- Trial name
- DEXDER (NCT02653378)
- Testing
- DIET, EX
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Covid19, Neurological Injury
Radiofrequency Intervention in Neurological Pathologies Post COVID-19
The sequelae that occur in post-COVID-19 patients are multiple and, at a therapeutic level, these represent a new challenge within the general context of the pandemic that the world is suffering.
- Conditions
- Covid19, Neurological Injury, Olfactory Disorder, Gustatory Agnosia
- Trial name
- NCT04920890
- Testing
- Radiofrequency therapy with manual therapy
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinica Gema Leon
Cystic Fibrosis With Other Manifestations, Sinusitis
Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell
Aim of the study is to detect the prevalence of chronic rhinosinusitis, pathogen colonization of the lower and upper airways and, in a sub-cohort the sense of smelling in patients with cystic fibrosis.
- Trial name
- NCT00803881
- Testing
- nasal lavage and sputum collection
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Jena
Olfactory Disorder, Taste Disorders
Prospective Registery of Smell/Taste Clinic Ear/Nose/Throat
Smell/taste disorders are common conditions with a significant impact on quality of life. In September 2021, a specific consultation for patients with smell and taste disorders was initiated at the ENT-HNS (ear, nose, and throat…
- Conditions
- Olfactory Disorder, Taste Disorders, Smell Dysfunction, Smell Disorder
- Trial name
- ProspeRo'Scent (NCT06456008)
- Testing
- Standard of care
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cystic Fibrosis in Children, Cystic Fibrosis
Sinus Disease in Young Children With Cystic Fibrosis
This is a prospective, observational study examining the impact of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators on chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) in young…
- Conditions
- Cystic Fibrosis in Children, Cystic Fibrosis, Chronic Rhinosinusitis (Diagnosis), Olfactory Disorder
- Trial name
- NCT06191640
- Testing
- Ivacaftor or elexacaftor/tezacaftor/ivacaftor
- Where
- 6 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Bacterial Vaginoses
Evaluate the Safety of a Single Oral Dose of Solosec™ (Secnidazole) 2g for the Treatment of Adolescent Girls With BV
A multi-center, open-label study to evaluate the treatment of one oral dose of 2g Solosec™ (Secnidazole) in adolescent girls with BV
- Trial name
- NCT03937869
- Testing
- Secnidazole
- Where
- 9 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lupin Research Inc
Post-covid-19 Persistent Smell and Taste Disorders
Clinical Characteristics and Treatment of Anosmia and Ageusia Due to SARS-CoV2 Variants
The SARS-CoV-2 pandemic has consisted of multiple surges of infection because of continuous viral mutations. The WHO and CDC have defined the main SARS-CoV-2 variants based on international and national data for the circulation…
- Trial name
- NCT06208540
- Testing
- Cerebrolysin, olfactory and gustatory trainings
- Where
- 2 sites in Egypt
- Volunteers
- 160 people
- Sponsor
- Sherifa Ahmed Hamed
Complete Spinal Cord Injuries
Transplantation of Autologous Olfactory Ensheathing Cells in Complete Human Spinal Cord Injury
The purpose of this experimental therapy is an assessment of the safety and feasibility of transplantation of autologous olfactory ensheathing glia and olfactory fibroblasts obtained from the olfactory mucosa in patients with…
- Trial name
- NCT01231893
- Testing
- olfactory mucosa ensheathing cell grafting, rehabilitation, rehabilitation
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Wroclaw Medical University
Autism, Smell Dysfunction
Ultramicronized Palmitoylethanolamide for Smell, Taste in Children With Autism Spectrum Disorder.
Autism Spectrum Disorder (ASD) is frequently associated with atypical sensory processing across visual, auditory, olfactory, and gustatory domains, variably affecting quality of life and requiring personalized treatment.
- Conditions
- Autism, Smell Dysfunction, Taste Alterations, Sensorial Disturbance
- Trial name
- SmeTasAu (NCT07631455)
- Testing
- supplement (Paidinil® HD, Epitech Group SpA, Saccolongo, Padova, Italy) containing 12% umPEA, Lactobacillus and Omega Fatty acids
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Campania Luigi Vanvitelli
Glaucoma
Assessment of the Ability to Distinguish Odors in Glaucoma Patients
Glaucoma is one of the leading causes of blindness worldwide. The key feature of glaucoma is damage to the optic nerve head with loss of retinal ganglion cells and local tissue remodeling.
- Trial name
- NCT00304824
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Taste Alterations, Smell Disorder
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents
Childhood cancer is a serious and life-changing disease that affects thousands of children every year worldwide. In addition to the disease itself, cancer treatments such as chemotherapy often cause difficult side effects.
- Conditions
- Taste Alterations, Smell Disorder, Eating Behavior Changes
- Trial name
- QUALISENS (NCT07490093)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Leon Berard