Clinical trials: Smokers
Pregnancy Related, Tobacco Smoking
Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns
Despite public campaigns to prevent cigarette smoking, it's about 20% of women who keep on smoking during pregnancy, exposing their fetus to prenatal tobacco adverse effects.
- Conditions
- Pregnancy Related, Tobacco Smoking, Lung Smokers, Newborn
- Trial name
- NCT03047967
- Testing
- lung function tests, Nasal brushing
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Asthma
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction.
- Trial name
- NCT01225913
- Testing
- fluticasone/salmeterol in all asthmatics, budesonide/formoterol or fluticasone/salmeterol in all asthmatics
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gelb, Arthur F., M.D.
Lung Cancer
LDCT Screening in Non-smokers in Taiwan
This study utilizes the low dose computed tomography(LDCT) to detect the occurrence of early lung cancer among non-smokers in Taiwan.
- Trial name
- NCT02611570
- Testing
- LDCT
- Where
- 17 sites in Taiwan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Academia Sinica, Taiwan
Field Cancerization for Cannabis Smokers
Effect of Cannabis and Cigarette Smoking on Oral Mucosa
The aim of this study is to detect P53 expression in clinically normal oral mucosa of cigarette smokers, simultaneous cigarette and cannabis smokers and non-smokers as a surrogate marker for field cancerization.
- Trial name
- NCT03334279
- Testing
- Cigarette smokers, Simultaneous cigarette and cannabis smokers
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Motivational Intervention, Nicotine Anonymous
Motivation and Skills for Detained Teen Smokers
The long-term objective of this research is to increase the investigators understanding of effective smoking interventions for understudied adolescents at high risk for continued smoking into adulthood.
- Conditions
- Motivational Intervention, Nicotine Anonymous, Cognitive Behavior Therapy, Relaxation Therapy
- Trial name
- NCT01387516
- Testing
- Motivational Intervention, Relaxation Therapy, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Alcohol Use Disorder (AUD), Alcoholism
Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer
Individuals with substance use disorders (SUD) have to cope with drug-related cues and contexts, which can affect instrumental drug seeking as shown with Pavlovian to instrumental transfer (PIT) paradigms in animals and humans.
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders, Smoking, Tobacco
- Trial name
- ReCoDe (NCT05992272)
- Testing
- fMRI imaging (BOLD), sMRI (structure), Trier Social Stress Test
- Where
- 2 sites in Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Smoking Cessation
A Phase I Study to Evaluate the Pharmacokinetics of Multiple Doses of Varenicline in Healthy Adolescent Smokers
This study will investigate the multiple dose pharmacokinetics, safety, and tolerability of two dose strengths of varenicline in adolescents aged 12 to 16 years who regularly smoke at least three cigarettes per day.
- Trial name
- NCT00463918
- Testing
- varenicline
- Where
- 16 sites in United States, United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Pfizer
Tobacco Addiction
High Cessation Rates in Smokers Using Personal Vaporizers
E-cigarettes are proving to be an attractive long-term alternative to conventional cigarettes. Although they may also help smokers to remain abstinent during their quit attempt, recent clinical trials with first generation…
- Trial name
- VAPECIG (NCT02124200)
- Testing
- EGO/CE4, 9mg nicotine
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Catania
Electronic Cigarette Use, Plaque Induced Gingivitis
Efficacy of Oral Hygiene Instructions on Proinflammatory Cytokines Among Cigarette Smokers and Individuals Vaping Electronic Cigarettes During Plaque Induced Gingivitis (Clinical Trial)
To evaluate the level of proinflammatory cytokines in individual vaping electronic cigarette in gingivitis patients. Can vaping affects the proinflammatory cytokines level in diseased individuals? Group I: cigarette smoker with…
- Trial name
- NCT06177158
- Testing
- oral hygiene instructions
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pregnancy, Smoking
A Mood Management Intervention for Pregnant Smokers
This proposal is aimed at testing the following hypotheses: 1. Cessation rates will be significantly greater for smokers in a mood management condition versus a health \& wellness condition during pregnancy and at 3 and 6 months…
- Trial name
- NCT00505869
- Testing
- Health & Wellness Intervention, Questionnaire, Mood Management Intervention
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- M.D. Anderson Cancer Center
Smoking, Acne
Sebum Collection and Skin Barrier Function Analysis
The goal is this study is to evaluate how the skin surface lipid composition is correlated with overall sebum production, barrier function, and inflammatory disease status.
- Conditions
- Smoking, Acne, Atopic Dermatitis, Aging
- Trial name
- Sebum (NCT03112876)
- Testing
- Skin Surface Lipid Collection and Skin Barrier Function
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy
Clinical Trial to Assess Pharmacodynamic Effects on Segmental Endotoxin Induced Inflammatory Response of BI 1026706 Versus Placebo
The primary and secondary objectives of the current study are the assessments of anti-inflammatory pharmacodynamic effects on segmental endotoxin induced inflammatory response after 4 weeks treatment with BI 1026706.
- Trial name
- NCT02657408
- Testing
- BI 1026706
- Where
- Germany
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Smoking Cessation
Promoting Smoking Cessation for Female Smokers in Hong Kong Through Training Female Youth SCRA
This project aims to promote quitting, and reduction for those who do not want to quit, among female smokers through training female youth as smoking cessation and reduction ambassadors (SCRA). The objectives are to: 1.
- Trial name
- NCT02755740
- Testing
- receiving age and gender-specific SC advice
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Cardiovascular Diseases, Heart Diseases
Recycling of Chronic Smokers to Sustained Abstinence
To develop and to test a brief telephone intervention following clinic treatment for smoking cessation.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases
- Trial name
- NCT00005710
- Sponsor
- University of Minnesota
Nicotine Dependence
Enhancing a High School Based Smoking Cessation Program
The purpose of this study is to examine the the efficacy of adjunctive nicotine replacement therapy when used in combination with the contingency management (CM) + cognitive behavioral therapy intervention.
- Trial name
- NCT01145001
- Testing
- Cognitive Behavioural Therapy, Contingency Management, Nicotine Transdermal Patch
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Yale University
Nicotine Dependence
Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Smokers
Background: Multiple social, psychological, and environmental factors contribute to adolescents' use of cigarettes. Environmental smoking cues have been shown to play an important role in the maintenance of nicotine addiction and…
- Trial name
- NCT01148355
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Smoking Cessation Study In Healthy Adolescent Smokers
The study is designed to see if varenicline combined with age appropriate (adolescent) smoking cessation counseling will help teens quit smoking.
- Trial name
- NCT01312909
- Testing
- Varenicline 1mg BID, Varenicline 0.5mg BID
- Where
- 80 sites in United States, Canada and 4 more
- Volunteers
- 312 people
- Sponsor
- Pfizer
Asthma
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction.
- Trial name
- NCT00576069
- Testing
- budesonide/formoterol, fluticasone/salmeterol, mometasone/formoterol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Gelb, Arthur F., M.D.
Adult Women, Overweight
Effects of Flaxseed Flour in Appetite Sensations, Lipid Profile and Pressure Levels Among Overweighed and Obese Women
Inclusion of foods rich in fiber, such as flaxseed, is a nutritional strategy for treating obesity. The hypothesis of this study is to compare the effects of three types of flaxseed flour - whole brown flaxseed flour, brown…
- Conditions
- Adult Women, Overweight, Obese
- Trial name
- NCT01549626
- Testing
- Defatted flaxseed flour, Golden flaxseed flour, Whole brown flaxseed flour
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Smoking Cessation
Smoking Cessation: Financial Incentives
The aim of this intervention is to test if the investigator, by offering a financial incentive to smokers who abstinence from smoking, can: 1.
- Trial name
- NCT03849092
- Testing
- Financial incentives, Campaigns
- Where
- Denmark
- Volunteers
- 1,934 people
- Sponsor
- Glostrup University Hospital, Copenhagen