Clinical trials: Smoking Reduction
Smoking, Passive Smoking
Prevent Exposure to Tobacco Smoke at Home [Gesunde Atemluft zu Hause]
Background: Infants are at risk for tobacco-attributable diseases by being exposed to environmental tobacco smoke (ETS). International literature has shown that a home smoking ban can reduce ETS.
- Conditions
- Smoking, Passive Smoking, Exposure to Environmental Smoke
- Trial name
- GESA (NCT00647413)
- Testing
- bio-chemical feedback and expert system intervention ETS
- Where
- Germany
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Smoking Cessation
Promoting Smoking Cessation for Female Smokers in Hong Kong Through Training Female Youth SCRA
This project aims to promote quitting, and reduction for those who do not want to quit, among female smokers through training female youth as smoking cessation and reduction ambassadors (SCRA). The objectives are to: 1.
- Trial name
- NCT02755740
- Testing
- receiving age and gender-specific SC advice
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Smoking Reduction, Asthma in Children
Early Life Intervention in Pediatrics Supported by E-health - SMOKE
Unrestricted parental smoking habits are lifestyle risk behaviors associated with chronic, systemic inflammation, which promotes the pathogenesis of non-communicable diseases (NCDs).
- Conditions
- Smoking Reduction, Asthma in Children, Wheezing, Non-Communicable Disease
- Trial name
- ELIPSE-II (NCT06311162)
- Testing
- Life-Style app
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Smoking Reduction, Smoking Cessation
Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana
The main purpose of this experimental study is to compare the existing health education program for School Health and Education Program (SHEP) in the Junior High Schools with a new health education model (Smart-Kids') for the…
- Conditions
- Smoking Reduction, Smoking Cessation, Smoking, Tobacco, Smoking Behaviors
- Trial name
- NCT04891939
- Testing
- Health education lessons (Smart-Kid's program), School Health and Education Program (SHEP)
- Volunteers
- 2,314 people, healthy volunteers welcome
- Sponsor
- Ghana Health Services
Smoking, Sexual Behavior
Linking Lives: Building Quality Parent Components for School-Based Health Programs in Middle Schools
The purpose of this study is to develop and evaluate the effectiveness of a parent-based intervention that can be implemented in conjunction with existing school-based programs designed to prevent or reduce sexual risk behavior…
- Trial name
- NCT00136279
- Testing
- Linking Lives parent-based intervention
- Where
- United States
- Volunteers
- 9,510 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Cardiovascular Diseases, Coronary Heart Disease Risk Reduction
Providers for Smoking Prevention Programs
To conduct a randomized controlled smoking prevention trial to evaluate quality of implementation and effectiveness, as a function of provider type (school teacher vs. nurse) and training (mediated vs. interactive).
- Conditions
- Cardiovascular Diseases, Coronary Heart Disease Risk Reduction, Heart Diseases, Lung Diseases
- Trial name
- NCT00005331
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Secondhand Smoke, Thirdhand Smoke
A Cluster-RCT of SHS Among Primary School Students
This is a school- and family-based prospective trial among Primary/Grade 2-4 (P2-4) students in randomly selected 12 schools in Hong Kong.
- Conditions
- Secondhand Smoke, Thirdhand Smoke, Smoking
- Trial name
- SHS-cRCT (NCT03380234)
- Testing
- Worksheets, Whatsapp messages, Online quizzes
- Where
- Hong Kong
- Volunteers
- 3,432 people
- Sponsor
- The University of Hong Kong
Asthma, Pulmonary Function
VCSIP Follow-up Study
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function and decrease wheeze at 5 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIPRenewal (NCT03203603)
- Testing
- No active intervention
- Where
- 2 sites in United States
- Volunteers
- 242 people
- Sponsor
- Oregon Health and Science University
Asthma, Wheezing
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on…
- Conditions
- Asthma, Wheezing, In Utero Nicotine, Pulmonary Function
- Trial name
- VCSIP-ECHO (NCT03206710)
- Testing
- No current intervention
- Where
- 2 sites in United States
- Volunteers
- 395 people
- Sponsor
- Oregon Health and Science University
Hypertension, Hyperlipidemia
Cardiovascular Lifestyle Study: Effects and Expense of a Cardiovascular Risk Reduction Clinic in Primary Care
The purpose of this trial is to study the effects on risk reduction and expense of 3 approaches to the care of people with cardiovascular risk factors in a naturalistic primary care environment.
- Conditions
- Hypertension, Hyperlipidemia, Hyperglycemia, Cardiovascular Disease
- Trial name
- NCT00291824
- Testing
- Cardiovascular risk factors and willingness to change
- Where
- Canada
- Volunteers
- 670 people
- Sponsor
- Caroline Medical Group
Alcohol Use, Smoking
Choices-Teen: A Bundled Risk Reduction Intervention for Juvenile Justice Females
This pilot study will: 1) demonstrate the feasibility of delivering CHOICES-TEEN with master's level mental health professionals within a juvenile justice setting; 2) determine acceptance of CHOICES-TEEN as measured by client…
- Conditions
- Alcohol Use, Smoking, Contraception, HIV
- Trial name
- NCT02252471
- Testing
- Choices-Teen
- Volunteers
- 28 people
- Sponsor
- University of Houston
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Smoking
Effectiveness of Intervention on Reducing the Prevalence of Smoking Among Adolescents
In this multicenter cluster randomized controlled trial stratified by school baseline prevalence of smoking will be randomly allocated to the control or intervention group.
- Trial name
- ITACA (NCT01602796)
- Testing
- School intervention
- Where
- 20 sites in Spain
- Volunteers
- 2,226 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Smoking Cessation
Pennsylvania Adolescent Smoking Study (PASStudy)
The Pennsylvania Adolescent Smoking Study (PASStudy) will evaluate the effectiveness of Motivational Interviewing (MI) compared to Structured Brief Advice (SBA) to reduce cigarette smoking among adolescents who smoke.
- Trial name
- NCT00381329
- Testing
- Motivational Interviewing (MI), Structured Brief Advice (SBA)
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- Pennsylvania Department of Health
Smoking Reduction
Cathelicidin LL-37 Levels in the GCF and the Saliva of Smokers and Non-smokers With Stage III,IV Periodontitis
Periodontitis is considered an inflammatory disease that results in the disruption of oral hemeostasis and is associated with the presence of dental plaque influenced by genetic and environmental factors.
- Trial name
- NCT04861493
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Smoking Cessation, Smoking Reduction
Detour: a Smartphone Game to Help Youth Quit Smoking
The researchers are testing a mobile game (named Detour) to support smoking cessation in adolescents and young adults (16-25 years).
- Conditions
- Smoking Cessation, Smoking Reduction, Adolescent Behavior, Social Behavior
- Trial name
- NCT06675526
- Testing
- Detour, Self-help brochure
- Where
- Netherlands
- Volunteers
- 604 people
- Sponsor
- Behavioural Science Institute
Cardiovascular Diseases, Heart Diseases
Trial of Smoking Cessation Programs in Black Churches
To provide a comprehensive description of smoking beliefs and behavior among rural Blacks, and to test the effectiveness of smoking cessation strategies delivered through Black churches.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Heart Disease Risk Reduction
- Trial name
- NCT00005689
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Smoking Reduction, Tobacco Use
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
This pragmatic trial will evaluate the value of routinely providing proactive smoking cessation support to current smokers as a part of participating in lung cancer screening within Veterans Health Administration.
- Conditions
- Smoking Reduction, Tobacco Use, Tobacco Smoking, Tomography
- Trial name
- PROACT (NCT03612804)
- Testing
- Unsigned note to provider about cessation medication prescription, Proactive Telephone Counseling from VA Quitline
- Where
- 3 sites in United States
- Volunteers
- 944 people
- Sponsor
- VA Office of Research and Development
Smoking Cessation
Factorial Design to Assess Quit-line Connections
Improved strategies and scalable interventions to engage low-socioeconomic status (SES) smokers in tobacco treatment are needed.
- Trial name
- NCT03760107
- Testing
- Connect Smokers to Treatment 1, Connect Smokers to Treatment 2, Connect Smokers to Treatment 3
- Where
- United States
- Volunteers
- 3,723 people
- Sponsor
- Minnesota Department of Health