Clinical trials: Smoking Reduction
Asthma, Wheezing
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on…
- Conditions
- Asthma, Wheezing, In Utero Nicotine, Pulmonary Function
- Trial name
- VCSIP-ECHO (NCT03206710)
- Testing
- No current intervention
- Where
- 2 sites in United States
- Volunteers
- 395 people
- Sponsor
- Oregon Health and Science University
Cardiovascular Diseases, Coronary Heart Disease Risk Reduction
Providers for Smoking Prevention Programs
To conduct a randomized controlled smoking prevention trial to evaluate quality of implementation and effectiveness, as a function of provider type (school teacher vs. nurse) and training (mediated vs. interactive).
- Conditions
- Cardiovascular Diseases, Coronary Heart Disease Risk Reduction, Heart Diseases, Lung Diseases
- Trial name
- NCT00005331
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Hyperlipidemia
Cardiovascular Lifestyle Study: Effects and Expense of a Cardiovascular Risk Reduction Clinic in Primary Care
The purpose of this trial is to study the effects on risk reduction and expense of 3 approaches to the care of people with cardiovascular risk factors in a naturalistic primary care environment.
- Conditions
- Hypertension, Hyperlipidemia, Hyperglycemia, Cardiovascular Disease
- Trial name
- NCT00291824
- Testing
- Cardiovascular risk factors and willingness to change
- Where
- Canada
- Volunteers
- 670 people
- Sponsor
- Caroline Medical Group
Cardiovascular Diseases, Heart Diseases
Trial of Smoking Cessation Programs in Black Churches
To provide a comprehensive description of smoking beliefs and behavior among rural Blacks, and to test the effectiveness of smoking cessation strategies delivered through Black churches.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Heart Disease Risk Reduction
- Trial name
- NCT00005689
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Smoking Cessation
Smoking Reduction: Testing a Novel Approach to Cessation in Primary Care Practice Settings
Traditional models of smoking cessation focus on delivering advice and counseling to quit and providing assistance to patients ready to quit smoking, but do not actively intervene with patients who are not ready to quit (NRTQ).
- Trial name
- NCT03128554
- Testing
- Intervention with Training and Materials
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Vaping Cessation
Nicotine Patch Plus Nicotine Mouth Spray Versus Nicotine Reduction for Vaping Cessation
This research focuses on maximizing the chances of successfully quitting vaping. A large, pragmatic community-based clinical trial is planned in New Zealand to build on existing evidence from previous vaping and smoking cessation…
- Trial name
- EQUIT3 (NCT06832098)
- Testing
- Nicotine patches plus nicotine mouth spray, Nicotine Tapering Plan
- Where
- New Zealand
- Volunteers
- 774 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Smoking Cessation
Factorial Design to Assess Quit-line Connections
Improved strategies and scalable interventions to engage low-socioeconomic status (SES) smokers in tobacco treatment are needed.
- Trial name
- NCT03760107
- Testing
- Connect Smokers to Treatment 1, Connect Smokers to Treatment 2, Connect Smokers to Treatment 3
- Where
- United States
- Volunteers
- 3,723 people
- Sponsor
- Minnesota Department of Health
Asthma, Pulmonary Function
VCSIP Follow-up Study
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function and decrease wheeze at 5 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIPRenewal (NCT03203603)
- Testing
- No active intervention
- Where
- 2 sites in United States
- Volunteers
- 242 people
- Sponsor
- Oregon Health and Science University
Smoking Reduction, Tobacco Use
Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
This pragmatic trial will evaluate the value of routinely providing proactive smoking cessation support to current smokers as a part of participating in lung cancer screening within Veterans Health Administration.
- Conditions
- Smoking Reduction, Tobacco Use, Tobacco Smoking, Tomography
- Trial name
- PROACT (NCT03612804)
- Testing
- Unsigned note to provider about cessation medication prescription, Proactive Telephone Counseling from VA Quitline
- Where
- 3 sites in United States
- Volunteers
- 944 people
- Sponsor
- VA Office of Research and Development
Smoking, Tobacco, Smoking Behaviors
The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy Evaluation
Few countries have legislation to reduce the number and types of tobacco retail outlets. The Netherlands plans to ban tobacco sales in supermarkets in 2024.
- Conditions
- Smoking, Tobacco, Smoking Behaviors, Smoking Cessation, Smoking Reduction
- Trial name
- NCT05554120
- Testing
- Supermarket tobacco sales ban
- Where
- Netherlands
- Volunteers
- 1,530 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center