Clinical trials: Sodium Bicarbonate
Myofacial Pain, Myofacial Pain Syndrome
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…
- Conditions
- Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- BIC-LIDO-MPS (NCT07572994)
- Testing
- Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Pediatric Dentistry
The Efficacy of Analgesic Buffering With Sodium Bicarbonate for the Pediatric Dental Patient
As a dentist, administering anesthetic to patients, especially children, proves to be one of the most difficult parts of a procedure. Pain is one of the most common symptom in dentistry, and a serious concern for the dentist.
- Trial name
- NCT01883232
- Testing
- Onset Mixing Pen by Onpharma, 2% lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Epilepsy, Metabolic Acidosis
Use of Sodium Bicarbonate in Patients Treated With Topiramate
Effect of oral sodium bicarbonate therapy on renal tubular acidosis in epilepsy patients taking topiramate.
- Conditions
- Epilepsy, Metabolic Acidosis, Tubular Acidosis; Renal
- Trial name
- NCT03354507
- Testing
- Sodium bicarbonate
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster Children's Hospital
Metabolic Acidosis; Critically Ill Patients; Organ Dysfunction
Risk Potential for Organ Dysfunction Associated With Sodium Bicarbonate Therapy (SBT) in Critically Ill Patients
This study aimed to investigate whether hemodynamic status before SBT contributed to the effect of sodium bicarbonate infusion on the risk of neonatal organ dysfunction and mortality in critically ill patients with early…
- Trial name
- NCT04953013
- Testing
- sodium bicarbonate
- Where
- China
- Volunteers
- 664 people
- Sponsor
- Peking University Third Hospital
Non-erosive Reflux Disease, Reflux Disease, Gastro-Esophageal
Evaluation of the Efficacy and Safety of Eolo in Patients With NERD
Background: Non-erosive reflux disease (NERD) is a prevalent subtype of gastroesophageal reflux disease (GERD), often inadequately managed with proton pump inhibitors (PPIs) alone.
- Conditions
- Non-erosive Reflux Disease, Reflux Disease, Gastro-Esophageal, Nutraceutical
- Trial name
- NCT07041060
- Testing
- EOLO, PPI (proton pump inhibitor), Group C: Eolo
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Bologna
Wound Healing
Wound Healing of Incisional Wounds for Bilateral Hernia Repair
The purpose of this research study is to test the safety of an oxygen producing gel (produced by combining baking soda and hydrogen peroxide) and see what effects (good and bad) it has on skin incisions in children.
- Trial name
- NCT01008111
- Testing
- Dermabond, Hydrogen Peroxide Oxygen producing gel
- Where
- United States
- Sponsor
- Wake Forest University
Labour Dystocia
Oral Sodium Bicarbonate for the Prevention of Labour Dystocia
Sodium bicarbonate is often used by athletes to improve their muscle's ability to contract and power their activity. It works by decreasing the risk of lactic acid build-up, which causes cramping and fatigue.
- Trial name
- Labour-Aide (NCT06249061)
- Testing
- oral sodium bicarbonate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Liz Darling
Sport Performance, Acid Base Imbalance
Effects of Single Sodium Bicarbonate Supplementation on National-Level Finswimming Performance
This randomized, double-blind, placebo-controlled crossover trial will investigate the acute effects of sodium bicarbonate supplementation on performance, stroke biomechanics, and selected physiological and perceptual responses…
- Conditions
- Sport Performance, Acid Base Imbalance, Ergogenic Support, Sodium Bicarbonate
- Trial name
- NCT07135934
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- Czechia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Palacky University
Chronic Kidney Diseases, Bone Loss
Bone in CKD Alkali Response (BICARb Pilot Trial)
The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease.
- Trial name
- BICARb (NCT05918029)
- Testing
- Potassium Citrate Extended Release Oral Tablet, Potassium Citrate and Citric Acid Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Albert Einstein College of Medicine
Oral Mucositis, Chemotherapy Effect
Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemotherapy
This study was planned as a randomized controlled experimental study in order to compare the effects of oral care with saline and black mulberry syrup in addition to sodium bicarbonate on oral mucositis level in children aged…
- Trial name
- NCT06525402
- Testing
- Sodium Bicarbonate Group (Usual care), Saline Group, Black Mulberry Syrup Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Allergic Rhinitis
Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study
The main objective of RinASol project is to assess in patients with seasonal Allergic Rhinitis the effect of hypertonic saline solution NACL 3%+NAHCO3 vs the effect of standard saline solution on nasal inflammation by means of…
- Trial name
- RinASol (NCT02729012)
- Testing
- hypertonic saline solution (NACL 3%+NAHCO3), Saline Solution (NACL 0,9%)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Stefania La Grutta, MD
Oral Mucositis
Effect of Black Mulberry Lollipop on Prevention of Oral Mucositis in Children
THE EFFECT OF BLACK MULBERRY LOLLIPOP AND SODIUM BICARBONATE USED IN ORAL CARE ON PREVENTION OF ORAL MUCOSITIS AMONG CHILDREN RECEIVING CHEMOTHERAPY DUE TO CANCER
- Trial name
- NCT04800549
- Testing
- Oral Mucositis
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sapanca Ilce Devlet Hastanesi
Supplementation, Sport
Sodium Bicarbonate Supplementation in Combat Sports Athletes
The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on physical and specific performance capacity, as well as concentrations of the selected biochemical blood…
- Trial name
- NCT03406065
- Testing
- Sodium bicarbonate supplementation
- Where
- Poland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Obstructed Labor
Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
The goal of this clinical trial is to determine a universal safe and effective dose of sodium bicarbonate for use among women with Obstructed labour to treat acidosis.
- Trial name
- SoBicOL-II (NCT06579690)
- Testing
- 8.4% sodium bicarbonate solution, 0.9% Normal Saline
- Where
- Uganda
- Volunteers
- 472 people
- Sponsor
- Busitema University
Upper Gastrointestinal Bleeding
Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill
Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage.
- Trial name
- NCT00045799
- Testing
- Omeprazole sodium bicarbonate immediate release PWD/FS, Cimetidine IV
- Where
- 58 sites in United States
- Volunteers
- 354 people
- Sponsor
- Bausch Health Americas, Inc.
Sarcoma, Oral Mucositis
Caphosol in Sarcoma Patients With Mucositis
The goal of this clinical research study is to find out if Caphosol® (calcium phosphate) mouthwash is more effective than a baking soda solution at preventing and treating mucositis, in patients with sarcoma who are to be treated…
- Trial name
- NCT00965172
- Testing
- Caphosol, Baking Soda
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Healthy, Athlete
Effects of Sodium Bicarbonate on Endurance Performance
This study is investigating whether taking sodium bicarbonate, a common supplement used by endurance athletes, can improve cycling performance during prolonged exercise and in a time trial.
- Conditions
- Healthy, Athlete, Well-trained Athletes, Performance
- Trial name
- SBEP (NCT07171047)
- Where
- Austria
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Salzburg
Verifying the Correct Position of Intravenous Catheters
Intravenous Sodium Bicarbonate Verifies Intravenous Position of Catheters in Children
Sodium bicarbonate injected into a blood vessel transforms to carbon dioxide and water. The increase in carbon dioxide production can be detected by measuring the exhaled carbon dioxide in the lungs.
- Trial name
- NCT01409083
- Testing
- intravenous sodium bicarbonate
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Sheba Medical Center
Ventilator-Associated Pneumonia
Oropharyngeal Care With Colostrum, Chlorohexidine and Sodium Bicarbonate in Preventing Ventilator-associated Pneumonia in Preterm Neonates
comparing the effect of oral care with colostrum, chlorohexidine and sodium bicarbonate in prevention of ventilator-associated pneumonia in preterm neonates.
- Trial name
- NCT07482007
- Testing
- Oropharyngeal Care with Colostrum, Chlorhexidine Oral Care, Sodium Bicarbonate oral care
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Cardiogenic Shock, High Risk PCI
Impella Real-World Surveillance of Patients Using Sodium Bicarbonate
The population enrolled in this study are all subjects who received an Impella in which a bicarbonate-based purge solution was used.
- Trial name
- NCT05820451
- Testing
- Impella CP, 2.5, 5.0 and 5.5 with Sodium Bicarbonate used as purge solution, Impella RP with Sodium Bicarbonate used as purge solution
- Where
- 20 sites in United States
- Volunteers
- 312 people
- Sponsor
- Abiomed Inc.