Clinical trials: Solid Cancer
Cancer, Brain Tumor
Medical Treatment Decision Making Using Adaptive Conjoint Analysis
In the setting of progressive or recurrent cancer, adolescent and young adult (AYA) patients, parents, and healthcare providers (HCP) are faced with multiple therapeutic options.
- Conditions
- Cancer, Brain Tumor, Solid Tumor, Leukemia
- Trial name
- NCT02608307
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Solid Tumor, Adult, Healthy Donors
A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.
Primary Objective: This is a study to investigate the feasibility of harvesting, expanding, and selecting T lymphocytes from cancer patients and healthy volunteers.
- Conditions
- Solid Tumor, Adult, Healthy Donors, COVID-19 Donors
- Trial name
- NCT00571389
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- BioCytics, Inc.
Unspecified Childhood Solid Tumor, Protocol Specific
Telephone-Based Cancer Education With or Without Telephone-Based Counseling in Young Participants
RATIONALE: Telephone-based cancer education and counseling may help participants learn about ways of preventing cancer and choose a lifestyle that will help them stay healthy as they grow older.
- Trial name
- NCT00459238
- Testing
- counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Georgetown University
H1N1 Influenza Virus, Invasive Solid Tumors
Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors
This is a phase III, randomized, controlled, open label study with two vaccine regimens. The study will assess the relative safety and immunogenicity of vaccine regimens comparing adjuvanted versus non-adjuvanted formulations of…
- Trial name
- NCT01031719
- Testing
- adjuvanted A(H1N1) influenza vaccine, non-adjuvanted A(H1N1) influenza vaccine
- Where
- 3 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Chiltern Pesquisa Clinica Ltda
COVID-19 Infection, Malignant Solid Neoplasm
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
This study uses questionnaires to gain an understanding of how experiences during the COVID-19 pandemic, regardless of COVID-19 status, may have impacted health-related quality of life (HRQOL) and other areas such as…
- Trial name
- NCT04447222
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Survey Administration
- Where
- United States
- Volunteers
- 1,242 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Culturally Informed Patient Navigation Program (CFPN) to Reduce Delays Between Diagnosis and Treatment in American Indian and Alaska Native Cancer Patients Living in Rural California
This clinical trial develops and tests whether a culturally informed patient navigation program, Community-Focused Patient Navigation (CFPN), works to reduce delays between diagnosis and treatment in American Indian and Alaska…
- Trial name
- NCT07332312
- Testing
- Discussion, Educational Intervention, Electronic Health Record Review
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Unspecified Adult Solid Tumor, Protocol Specific
Promoting Physical Activity In After-School Programs for Urban Adolescents
RATIONALE: Physical activity may lower the risk of some types of cancer and other chronic diseases. PURPOSE: This clinical trial is studying ways to increase physical activity in urban adolescents who attend after-school programs.
- Trial name
- NCT00301158
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy Volunteers, Recurrent Glioma
MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
This first-in-human study will establish the human safety and radiation dosimetry of the system A amino acid transport substrate, (R)-3-[F-18]fluoro-2-methyl-2-(methylamino)propanoic acid ([F-18]MeFAMP), for positron emission…
- Conditions
- Healthy Volunteers, Recurrent Glioma, Brain Metastases From Extra-cranial Solid Tumors
- Trial name
- NCT05676489
- Testing
- [F-18]MeFAMP PET
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Carcinoma, Colorectal Carcinoma
Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
This trial assesses current biomarker testing practices for common solid cancers in precision oncology in the community setting.
- Conditions
- Breast Carcinoma, Colorectal Carcinoma, Community Practice, Lung Carcinoma
- Trial name
- NCT03804255
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors
The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in…
- Trial name
- NCT05138991
- Testing
- Echocardiogram Recording, Questionnaire Administration, Stress Cardiac Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Neuroblastoma, Sarcoma
Pediatric Solid Tumor Metabolism [A Prospective Study Exploring Metabolism of Solid Tumors in Pediatrics]
To explore metabolic phenotypes of children with extra-cranial solid tumors and compare these with their histopathological and genetic alterations to discover potential novel biomarkers and therapeutic targets to improve outcomes…
- Conditions
- Neuroblastoma, Sarcoma, Pediatric Cancer
- Trial name
- NCT03686566
- Testing
- 13C-glucose, No glucose infusion
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Solid Tumor
The Molecular Imaging Research of F-18 Labeled DX600 PET Probe
Angiotensin-converting enzyme 2 (ACE2) plays an important role in renin-angiotensin system (RAS) and has been reported to relate with cancer. Recently, it has also been proved as the key target for COVID-19 infection.
- Trial name
- NCT04542863
- Testing
- 18F-DX600 PET/CT
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Pediatric Solid Malignancies, Pediatric Hematological Malignancies
Neutrophil Extracellular Traps (NETs) Formation Following Chemotherapy and Their Role in Antitumor Activity
Examine neutrophil extracellular traps (NETs) formation, in relation to other neutrophil functions like chemotaxis, superoxide production, hydrogen peroxide production, and the presence of myeloperoxidase, in pediatric patients…
- Trial name
- NCT01533779
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Neoplasms, Hematologic Neoplasms
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
This study will collect biological samples for use in research experiments aimed at better understanding the clinical features of certain diseases.
- Conditions
- Neoplasms, Hematologic Neoplasms, Healthy Volunteers
- Trial name
- NCT00071045
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Minimal Residual Disease, Fertility Preservation
Contamination of Ovarian Tissue by RT-PCR in Participants With Solid Tumors
For prepubertal patients, cryopreservation of ovarian tissue is the only option available to preserve their fertility before cancer treatment.
- Trial name
- OVAMAR (NCT02400827)
- Testing
- malignant cells
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pediatric Solid Tumor, Unspecified, Protocol Specific
Liquid Biopsies in Pediatric Solid Tumors
This study is being done to determine if traces of tumor can be found in the blood before, during, and after patients stop treatment.
- Trial name
- NCT05068583
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
The Impact of COVID-19 on Pulmonary Procedures
This study investigates the changes in practice by pulmonary procedural programs across the United States as they faced the coronavirus pandemic.
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05022446
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Childhood Cancer, Hematopoietic and Lymphoid Cell Neoplasm
Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care
This clinical trial studies the effectiveness of a newly developed survivorship mobile application (app) designed for survivors, or their caregivers, of childhood cancer to help them better navigate long-term follow-up care.
- Conditions
- Childhood Cancer, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05641961
- Testing
- Survivorship mobile application, Questionnaires
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer, Solid Tumors
Collection of Pharmacokinetic Samples From People With Unanticipated Response, Significant Toxicity or Concern of Future Toxicity
Background: Certain drugs - even when they are meant to help people - cause side effects. These are unwanted effects of the drug. There are many reasons why a drug might cause side effects in one person and not in another.
- Conditions
- Cancer, Solid Tumors, Neoplasm
- Trial name
- NCT02154022
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)