Clinical trials: Sore-throat
Tonsillitis
Children Recovering From Tonsil Surgery
Children recovering from tonsil surgery following day surgery Tonsil surgery - self-care and treatment - the TONIST-study The main objective of this study is to evaluate the effect and experience of acupuncture, acupressure…
- Trial name
- TONIST (NCT03292068)
- Testing
- Acupuncture, acupressure, Timbal diet, Extended telephone counseling
- Where
- Sweden
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Lund University
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Acute Respiratory Tract Infection, Otitis Media
Broad Implementation of Outpatient Stewardship
Reducing inappropriate antibiotic use is a key strategy to mitigate antibiotic resistance and adverse health effects associated with antibiotic exposure.
- Conditions
- Acute Respiratory Tract Infection, Otitis Media, Pharyngitis, Acute Sinusitis
- Trial name
- BIOS (NCT05127161)
- Testing
- Broad Implementation of Outpatient Stewardship (BIOS) intervention
- Where
- 5 sites in United States
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Laryngopharyngeal Reflux, Throat Pain
Anti-reflux Control to Decrease Post Tonsillectomy Pain
The study aims to determine if treating pediatric patients (age 7-17) for four weeks with omeprazole prior to tonsillectomy will decrease post tonsillectomy pain.
- Trial name
- NCT01777854
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Obstructive Sleep Apnea, Tonsillitis
Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery
A RCT to compare hydromorphone versus fentanyl for pain control following tonsillectomy or adenotonsillectomy surgery.
- Trial name
- NCT04230681
- Testing
- Hydromorphone, Fentanyl
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Tonsillitis, Tonsillectomy
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic…
- Trial name
- NCT03625011
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Streptococcus Group A
Molecular Epidemiology of Streptococcus Pyogenes Among Children in Bamako, Mali
The purpose of this study is to learn more about sore throats caused by the germ Group A Streptococcus (GAS) or "Strep". When "Strep" causes a sore throat, it can be treated with medicines called antibiotics.
- Trial name
- NCT00305123
- Where
- Mali
- Volunteers
- 1,757 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
OSAS, Recurrent Tonsillitis
ASSESMENT OF TONSIL VOLUME WITH ULTRASONOGRAPHY IN BOTH CHILDREN AND ADULTS
The tonsil volume is an important factor in the decision of the tonsillectomy operation. For this reason, it is important to evaluate the tonsil size before the surgery.
- Trial name
- NCT04030156
- Testing
- tonsillectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Tonsillitis, Hypertrophy
Immune Response To Intranasal Influenza Vaccination
This research during the last decade has focused on the kinetics of the systemic and local immune response to parenteral influenza vaccine in humans.
- Trial name
- NCT01866540
- Testing
- FLUENZ
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Obstructive Sleep Apnea, Tonsillitis
Pediatric Pain Optimization After Tonsillectomy
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.
- Conditions
- Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
- Trial name
- NCT05244226
- Testing
- Fentanyl/Hydromorphone, Methadone
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Sore Throat, Cough, Hoarseness
Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure
Endotracheal Tube (ETT) is frequently used for GA (general anesthesia) to deliver oxygen and volatile anesthetic agents to the patient and serves as a channel for anesthetic gases.
- Trial name
- NCT07315490
- Testing
- Xylocaine
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PAEC General Hospital, Islamabad
Acute Otitis Media (AOM), Strep Pharyngitis
Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma
This study evaluates the diagnostic performance, usability, and clinical utility of the Medentum Diagnostik platform, a multisensor device with integrated software and artificial intelligence, in pediatric patients with asthma…
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Trial name
- NCT07500532
- Testing
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medentum Innovations
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Fever, Sore Throat
Thermographic Characteristics of Sore Throat by Thermographic Camera
Thermographic cameras are used to determine temperature and temperature differences. Attempts have been made to use the thermographic camera as a diagnostic tool in clinical practice.
- Trial name
- thermography (NCT01782183)
- Testing
- Thermal camera by Flir -HM series.
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Doron Carmi
Tonsillitis
Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy
The primary purpose of this study is: 1. To compare dexmedetomidine with fentanyl in terms of intra-operative hemodynamics and post-operative analgesia. 2. To determine an analgesic dose response relationship for dexmedetomidine.
- Trial name
- DexT&A (NCT00654511)
- Testing
- Fentanyl, Dexmedetomidine
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Tonsillitis
Effectiveness of Tonsil Fossa Closure in Pain Relief After Tonsillectomy in Children
Objective: Postoperative pain is the main complaint in children undergoing tonsillectomy. An inexpensive method and with few evidence in the literature on effectiveness in reducing pain is the closure of the tonsillar fossa by…
- Trial name
- NCT02676583
- Testing
- Tonsillectomy
- Where
- Brazil
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Marco Aurelio Fornazieri
Streptococcus Group A
Incidence of Group A Strep Pharyngitis in School Children in Fiji
The purpose of this study is to find out how often group A Streptococcus (GAS) occurs in school-age children of Central Fiji. This bacterium often causes pharyngitis (sore throat) and can also cause pyoderma (skin infection) or…
- Trial name
- NCT00284882
- Where
- Fiji
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Rheumatic Heart Disease in Children
School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions
The overall objective of the PREVENT trial is to evaluate the effectiveness of an integrated, school-based program for the prevention of rheumatic heart disease (RHD) in regions with an endemic pattern of RHD.
- Trial name
- PREVENT (NCT06720272)
- Testing
- School nurse program
- Where
- 2 sites in Nepal, Zambia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Thomas Pilgrim