Clinical trials: Sound Therapy
Asthma, Acute Asthma
Budesonide for Emergency Treatment of Acute Wheezing in Children
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in the emergency room.
- Trial name
- NCT00733317
- Testing
- 0.5 mg/ml budesonide nebules, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kecioren Education and Training Hospital
Speech Sound Disorder
Dynamic Assessment of Phonological Disorders
The goal of this clinical trial is to learn about (1) how speech skills can be measured and how various tests give speech therapists different types of information for children with speech sound disorder, and (2) whether changes…
- Trial name
- NCT06075303
- Testing
- Modified Cycles
- Volunteers
- 4 people
- Sponsor
- University of Montana
Speech Sound Disorder
AI-Assisted Treatment for Residual Speech Sound Disorders
The goal of this randomized-controlled trial is to determine how artificial intelligence-assisted home practice may enhance speech learning of the "r" sound in school-age children with residual speech sound disorders.
- Trial name
- NCT05988515
- Testing
- Speech-Language Pathologist-led Speech Motor Chaining, Artificial Intelligence-led Speech Motor Chaining (CHAINING-AI)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Speech Sound Disorders
New Therapeutical Perspectives in Cases of Phonological Disorders
The aim of this study is to verify phonological and auditory aspects of children submitted to traditional phonological therapy, phonological therapy using a software and placebo therapy in children with phonological disorders.
- Trial name
- NCT02935062
- Testing
- Traditional Phonological Therapy, Software Phonological Therapy- SIFALA
- Where
- 2 sites in Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Bronchiolitis, Wheezing
Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants
Determine the efficacy of nebulized salbutamol/hypertonic saline combination in moderate to severe bronchiolitis.
- Trial name
- NCT02233985
- Testing
- 0.9% Sodium Chloride, 3% Sodium Chloride
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Speech Sound Disorder, Language Development Disorders
Exploratory Trial of the "HiDongDong" Language Rehabilitation App for Articulation Delay.
The purpose of this study is to evaluate the effectiveness of the AI-based application "HiDongDong" in improving articulation development in children aged 2 to under 14 years with suspected articulation delays.
- Conditions
- Speech Sound Disorder, Language Development Disorders, Phonological Disorder
- Trial name
- NCT07613268
- Testing
- HiDongDong Intervention, Standard Care / Speech Therapist Intervention
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Seoul National University Bundang Hospital
Recurrent Wheezing, Wheezing Lower Respiratory Illness
A Study to Assess the Efficacy and Safety of Daily OM-85 in Young Children With Recurrent Wheezing
This study will assess the efficacy and safety of daily OM-85 treatment compared to placebo in children aged 6 months to 5 years with recurrent wheezing
- Trial name
- NCT05857930
- Testing
- OM-85
- Where
- 38 sites in United States, Australia and 2 more
- Volunteers
- 296 people
- Sponsor
- OM Pharma SA
Wheezing
Bronchodilators for Wheeze in Young Children Presenting to Primary Care: a Randomised, Placebo-controlled, Multicentre, Parallel Group Trial
Ten percent of infants are prescribed short-acting bronchodilators (i.e. salbutamol) for wheezing every year, yet evidence to support this treatment in children younger than two years old is scarce.
- Trial name
- KIWI (NCT04584034)
- Testing
- Salbutamol
- Sponsor
- UMC Utrecht
Speech Sound Disorder
Treatment Targets in Spanish and English Bilingual Speech Intervention
The goal of this clinical trial is to learn which speech treatment targets result in the greatest amount of speech learning in Spanish-English bilingual children with speech sound disorders.
- Trial name
- NCT06416306
- Testing
- Speech Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Philip Combiths
Speech Articulation Disorder, Developmental Articulation Disorder
Randomized Clinical Trial of Phonological Interventions
Recent research reveals genetic and symptomatic overlap among children with speech sound disorders (i.e., those who (misarticulate more sounds than would be expected for their age) and children with dyslexia (i.e., those who…
- Conditions
- Speech Articulation Disorder, Developmental Articulation Disorder, Phonological Impairment, Dyslexia
- Trial name
- ECRIP (NCT00818428)
- Testing
- Speech Production Intervention, Speech Perception Intervention, Articulation Parent Group
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- McGill University
Chronic Obstructive Pulmonary Disease
A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD)
A real world study to determine the effectiveness of a patient support service to aid COPD patients in their self management.
- Trial name
- Me&MyCOPD (NCT02300090)
- Testing
- Test Group, Control Group
- Where
- 23 sites in United Kingdom
- Volunteers
- 161 people
- Sponsor
- AstraZeneca
Speech Sound Disorder
staRt: Enhancing Speech Treatment With Smartphone-delivered Biofeedback
Previous research suggests that biofeedback can outperform traditional interventions for RSE, but no controlled studies have tested this hypothesis in the context of app-delivered biofeedback.
- Trial name
- staRt (NCT04474691)
- Testing
- Traditional articulation treatment, Visual-acoustic biofeedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York University
Stridor
Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children
The study aims to analyze and compare the clinical effects of using inhaled budesonide or intravenous dexamethasone in the treatment of postextubation stridor on children admitted to the pediatric intensive care units at Hospital…
- Trial name
- BUDEXA (NCT02056379)
- Testing
- Budesonide, Dexamethasone
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Israelita Albert Einstein
Pediatric Respiratory Diseases, Asthma
Analysis of Lung Sounds Collected by RESP Biosensor to Support Decision Making in Monitored Hospitalized Pediatric Patients
This observational clinical trial is designed to confirm whether RESP™ Biosensor could be deployed to support clinical decision making in challenging pediatric cases, minimize clinician-to-clinician variability in lung sound…
- Conditions
- Pediatric Respiratory Diseases, Asthma, RSV Infection, COVID-19
- Trial name
- NCT05661422
- Testing
- RESP™ Biosensor
- Where
- United States
- Sponsor
- Strados Labs, Inc.
Hyperacusis
Intervention for Reduced Sound Tolerance
Hyperacusis is the intolerance to sound levels that normally are judged acceptably loud to others. The presence of hyperacusis (diagnosed or undiagnosed) can be an important reason why some persons reject amplified sound from…
- Trial name
- NCT00890526
- Testing
- Sound Therapy (Tinnitus Retraining Therapy), Counseling (Tinnitus Retraining Therapy), No Counseling
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama, Tuscaloosa
Emotional Dysregulation, Therapeutic Alliance
Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth
Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public health systems.
- Conditions
- Emotional Dysregulation, Therapeutic Alliance, Depression Disorder, Anxiety Disorders
- Trial name
- HEAL-SLOJSC (NCT07364799)
- Testing
- Multi-sensory emotional regulation intervention (Heal)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- SoundHeal
Cleft Palate Children, Speech Sound Disorder
Speech Intervention Via Telepractice for Children With Repaired Cleft Palate
The goal of this interventional study is to see if online speech therapy works just as well as face-to-face speech therapy in children with cleft palate.
- Trial name
- NCT07434375
- Testing
- Speech therapy via teleprace, Face-to-face speech therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Texas Tech University Health Sciences Center
Congenital Hearing Loss
a Study in Subjects With Otoferlin Mutation-related Hearing Loss Using RNA Base-eDiting Therapy(SOUND)
The purpose of the study is to determine whether HG205 as CRISPR/Cas13 RNA base-editing therapy is safe and effective for the treatment of hearing loss caused by p.Q829X mutation in OTOF gene.
- Trial name
- NCT06025032
- Testing
- HG205
- Where
- China
- Sponsor
- HuidaGene Therapeutics Co., Ltd.
Asthma, Inflammation
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing
The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus…
- Trial name
- INSTAR (NCT03889743)
- Testing
- Dexamethasone treatment during 3 days
- Where
- 8 sites in Finland, Norway and 1 more
- Volunteers
- 280 people
- Sponsor
- St. Olavs Hospital
Asthma, Wheezing
AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department
AZ-SWED is a parallel group, double blind, placebo control efficacy clinical trial with two separate hypotheses. The trial compared the 5-day outcome of preschool children presenting to an Emergency Department (ED) with an acute…
- Trial name
- AZ-SWED (NCT04669288)
- Testing
- Azithromycin
- Where
- 8 sites in United States
- Volunteers
- 840 people
- Sponsor
- University of Arizona