Clinical trials: Spasticity
Cerebral Palsy, Spastic, Children, Only
Efficacy of a Long Term, High Intensity and Long Time Stretch Training Program on Viscoelasticity Plantarflexors Muscle in Children With Cerebral Palsy (CP).
Children with cerebral palsy present early in the childhood altered muscular properties, as soon as structural or stiffness. In the gastrocnemius muscle, altered muscular properties are characterized by short muscle belly length…
- Trial name
- LONGSTRETCH PC (NCT03565172)
- Testing
- isokinetic dynamometer with ultrasound, Visual Analog Scale (VAS), Stretching
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cerebral Palsy Spastic Diplegia
FES Assisted Cycling in Children With CP
This project proposes to assess if Functional Electrical Stimulation (FES) assisted cycling can improve the cycling ability, muscle strength, cardiovascular health, quality of life, self perception and functional mobility of…
- Trial name
- CP FES Cycling (NCT04688424)
- Testing
- FES, Cycling
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Equinus Deformity
Dynamic Evaluation of Ankle Joint and Muscle Mechanics in Children With Spastic Equinus Deformity Due to Cerebral Palsy
This research will lead to the first evaluation of intrinsic and dynamic joint and muscle mechanics of equinus in cerebral palsy. It would provide a direct cause and effect relationship between equinus and bone deformity.
- Trial name
- EQUINUS (NCT02814786)
- Testing
- MRI scanner, Gait analysis
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Spastic Cerebral Palsy
Dual Task Training in Spastic Cerebral Palsy
Cerebral palsy(CP) is a non-progressive disorder, undergoing mishap to the developing brain and it affect a person's ability to move and maintain balance and posture. Old name of CP is "Little's disease".
- Trial name
- NCT06407856
- Testing
- conventional therapy, Dual Task Training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Cerebral Palsy
Treadmill With Ankle Weights on Balance in Spastic Cerebral Palsied Children
The purpose of the study is to investigate the effect of treadmill training combined with ankle weights on balance in spastic cerebral palsied children.
- Trial name
- NCT05106829
- Testing
- Physical therapy program with treadmill training without using of ankle weights., Physical therapy program with treadmill training with using of ankle weights.
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Functional Electrical Stimulation, Cerebral Palsy
Functional Electrical Stimulation With Core Stabilization Exercises in Children With Spastic Diplegia
This study was done to: investigate the combined effect of functional electrical stimulation with core stabilization exercises on pelvic tilting in children with spastic diplegia.
- Conditions
- Functional Electrical Stimulation, Cerebral Palsy, Core Stability
- Trial name
- NCT07110025
- Testing
- designed physical therapy program, core stabilization exercise with neuromuscular electrical stimulation
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic
Effect of Motor Imagery Training on Gait and Balance in Children With Spastic Hemiplegia
This study aims to: Investigate the effect of motor imagery training on gait kinematics in children with spastic hemiplegia. Determine the effect of motor imagery training on balance in children with spastic hemiplegia.
- Trial name
- NCT04765917
- Testing
- Selected physical Therapy program, Motor imagery training program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Spasticity Due to Cerebral Palsy
Phase 1b Study of Tizanidine in Pediatric Patients With Cerebral Palsy
A Single-Dose, Phase 1b, Multicenter, Open-Label Study to Assess the Pharmacokinetics, Safety and Tolerability, and Pharmacodynamics of Tizanidine at 4 Different Oral Dose Levels in Pediatric Subjects 2 to 16 Years Old With Mild…
- Trial name
- NCT01405950
- Testing
- Zanaflex Capsules
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Acorda Therapeutics
Spastic Cerebral Palsy
Video Based Games Exercise Training in Individuals With Cerebral Palsy
Cerebral palsy (CP) is a non-progressive neurological disorder characterized by a persistent decline in sensory, cognitive or especially gross and fine motor functions during infancy or early childhood.
- Trial name
- NCT06073743
- Testing
- Conventional Physiotherapy, Video Game Based Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy, Spastic
Application of 3D Scanner to Measure Physical Size in Patients With Severe Cerebral Palsy
The aim of this study is to improve the manufacturing techniques of hip brace in preventing progressive hip displacement in patients with severe cerebral palsy, through the measurement of patient's physical size using a 3D…
- Trial name
- NCT05388422
- Testing
- Application of 3D scanner to measure physical size in patients with severe cerebral palsy
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Seoul National University Hospital
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Spastic Cerebral Palsy
Short Term Follow-up of a Botulinum Toxin Intervention in Children With Spastic Cerebral Palsy
This study investigates the effect of integrated Botulinum Neurotoxin A (BoNT) treatment on morphologic muscle and tendon properties, spasticity, joint stiffness, joint range of motion, muscle strength, gait and gross motor…
- Trial name
- NCT05126693
- Testing
- Botulinum Toxin treatment combined with a post-BoNT intensive physical therapy period guided by individualized treatment goals.
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy
Effect of Botulinum Toxin on Muscles of Children With Cerebral Palsy
Cerebral palsy (CP) is a group of non-progressive motor dysfunction but often changing, secondary to injury or brain abnormalities that occur in early stages of development.
- Trial name
- TOXIMUS_CP (NCT02853240)
- Testing
- Muscle biopsy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy, Spastic
The Effects of Intensive Therapy on Trunk and Lower Limbs in Children With Spastic Cerebral Palsy.
Research on the effects of physiotherapeutic interventions in children with CP has grown expansively, and shows a wide diversity of techniques and concepts that are used in variable intensity.
- Trial name
- NCT03449498
- Testing
- Qualitative functional therapy, Functional therapy
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- University Ghent
Dystonia
Theta-burst Transcranial Magnetic Stimulation
Theta-burst transcranial magnetic stimulation (TBS) is a type of repetitive transcranial magnetic stimulation (rTMS) method that reduces the excitability of a small region of brain for less than one hour.
- Trial name
- NCT00878787
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Southern California
Spastic Cerebral Palsy
Whole Body Vibration and BOSU Ball in Spastic Cerebral Palsy
Cerebral palsy is a non-progressive neurodevelopmental disorder, also known as littles disease. The most common cause of physical and mental disabilities in the pediatric population.
- Trial name
- NCT06407921
- Testing
- Whole Body Vibration, BOSU ball
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP)
Upper Extremity Strengthening Interventions in Children With UCP
This study aims to compare the effects of two different upper extremity strengthening exercise approaches-bilateral strengthening exercises based on Proprioceptive Neuromuscular Facilitation (PNF) patterns and plyometric…
- Trial name
- PNF vs PLY-UCP (NCT07116798)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Biruni University
Cerebral Palsy (CP)
Effects of Circuit Training and Task Oriented Training on Balance and Quality of Life in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is a group of permanent disorders affecting movement and posture, caused by non-progressive disturbances in the developing fetal or infant brain.
- Trial name
- NCT07799064
- Testing
- Group A Circuit Training, Group B Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- Ibadat International University, Islamabad
Spastic Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
Halliwick Concept on Motor Functions in Spastic CP
This randomized controlled trial will investigate the effect of hydrotherapy (halliwick concept) on motor functions in children with spastic cerebral palsy (CP). Minimum of 30 Spastic CP children will be recruited for this study.
- Trial name
- NCT05094921
- Testing
- Aquatic Halliwick method, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- October 6 University
Mitochondrial Encephalomyopathies, Hereditary Spastic Paraplegia
Natural History Study of Patients with HPDL Mutations
This study uses medical records that allow retrospective data extraction of clinical manifestation to assess the natural history of HPDL mutations
- Conditions
- Mitochondrial Encephalomyopathies, Hereditary Spastic Paraplegia, Spastic Paraplegia, White Matter Disease
- Trial name
- NCT05848271
- Testing
- Patient Registry, Dry blood spots sampling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego