Clinical trials: Spasticity
Cerebral Palsy, Cerebral Palsy, Spastic
An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy
The study is to evaluate the effectiveness of hyperbaric treatments and the potential longer-term effects in children between the ages of 3 and 8 years with spastic cerebral palsy (CP).
- Trial name
- NCT00290186
- Testing
- Hyperbaric Oxygen Treatment, Hyperbaric Air Treatment
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Dayton Children's Hospital
Cerebral Palsy
Comparison of Constraint-Induced Movement Therapy And Bimanual Intensive Therapy Through Tele-rehabilitation For CP
Cerebral palsy is a neurological condition affecting movement and posture, caused by non-progressive brain disruptions occurring during fetal development.
- Trial name
- NCT06658275
- Testing
- Constraint-induced movement therapy, Hand Arm Bimanual Intensive Training -HABIT
- Volunteers
- 65 people
- Sponsor
- Riphah International University
Diplegic Cerebral Palsy
Dynamic Orthotic Garment in Diplegic Cerebral Palsy
This study aims to evaluate the effectiveness of dynamic orthotic garment (Thera togs) on foot pressure distribution, postural control, functional performance and endurance in children with spastic diplegic cerebral palsy (CP).
- Trial name
- NCT05271149
- Testing
- Routine Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Taibah University
Physical Therapy
Feasibility Of Oral Sensorimotor Stimulation On Oropharyngeal Dysphagia In Children With Spastic Cerebral Palsy
Children with CP encounter swallow and feeding impairments, especially in infancy and childhood with long meal times with late development of oral motor skills resulting in poor growth.
- Trial name
- NCT04524559
- Testing
- conventional physical therapy training, oral motor training.
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hereditary Spastic Paraplegia Type 5
PCSK9 Inhibitor Treatment for Patients With SPG5
Spastic paraplegia type 5 (SPG5) is a rare subtype of hereditary spastic paraplegia, a highly heterogeneous group of neurodegenerative disorders defined by progressive neurodegeneration of the corticospinal tract motor neurons.
- Trial name
- NCT04101643
- Testing
- evolocumab
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Gait Disorders in Children, Cerebral Palsy Spastic Diplegia
Comparison of Walking Parameters Between Idiopathic Toe Walking and Independent Walking Diparetic Cerebral Palsy
The aim of the observational study is to compare static, kinematic and kinetic parameters with normal gait parameters in cases with Idiopathic toe walking (ITW) and Diparetic Cerebral Palsy (DCP) who have Gross Motor Function…
- Trial name
- NCT06142721
- Testing
- 3D Gait Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Biruni University
Diplegic Cerebral Palsy With Spasticity, Motor İmagery Ability
Motor Imagery and Functional Performance in Diplegic Cerebral Palsy
The main purpose of this study was to examine the relationship between motor imagery capacity and functional mobility, walking and balance in children with diplegic type cerebral palsy.
- Trial name
- NCT07287215
- Testing
- Motor Imagery Ability Assessment, Mental Stopwatch Paradigm, Functional Mobility
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Inonu University
Cerebral Palsy
EXOPULSE Mollii Suit & Cerebral Palsy
Spasticity is a frequent and debilitating symptom in patients with cerebral palsy. It can alter the patients' balance, mobility, as well as their quality of life (QoL).
- Trial name
- EXOCEP (NCT06266286)
- Testing
- EXOPULSE MOLLII SUIT (active)
- Where
- 4 sites in France
- Volunteers
- 32 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Cerebral Palsy, Acquired Brain Injury
Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat
The use of robotic technologies in rehabilitation is an increasingly widespread practice in the health sector: the Lokomat is a medical device intended for walking rehabilitation, consisting of an exoskeleton, a treadmill and a…
- Conditions
- Cerebral Palsy, Acquired Brain Injury, Hereditary Spastic Paraplegia
- Trial name
- NCT05767268
- Testing
- Lokomat
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea
Muscle Spasticity
Spasticity Registry Evaluating Epidemiology, Treatment Patterns and Clinical Needs
This study will examine the epidemiology (incidence and control of a disease), burden, clinical need, and treatment patterns of spasticity in patients with a diagnosis of Cerebral Palsy (CP), Multiple Sclerosis (MS), Stroke…
- Trial name
- STRETCh (NCT02145650)
- Testing
- No Intervention
- Where
- United States
- Sponsor
- Allergan
Cerebral Palsy
The Effect of Botulinum Toxin Injection at Hip Adductor Muscles in Patients With Spastic Cerebral Palsy, Pilot Study
In children with cerebral palsy, secondary problems lead to hip dislocation. the purpose of this study is to find out the effects of botulinum toxin A on hip joint dislocation in cerebral palsy patients.
- Trial name
- NCT03680196
- Testing
- medication Botulinum A injection.
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Ju Seok Ryu
Cerebral Palsy
The Effect of Instrument Assisted Soft Tissue Mobilization and Stretching Exercises in Cerebral Palsy
The aim of the study; To investigate the effects of Instrument Assisted Soft Tissue Mobilizations and Stretching Exercises on flexibility, spasticity, balance and functional mobility in patients with CP.
- Trial name
- IASTM (NCT05042570)
- Testing
- Instrument Assisted Soft Tissue Mobilization, Stretching Exercises, Control Group / NDT program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Spastic Diplegia
Phase II Randomized Study of Selective Dorsal Rhizotomy and Physiotherapy Vs Physiotherapy Alone for Spastic Diplegia
OBJECTIVES: I. Assess the efficacy and safety of selective dorsal rhizotomy and physiotherapy compared with physiotherapy alone in improving gross motor function and reducing spasticity in children with spastic diplegia.
- Trial name
- NCT00004751
- Testing
- Surgery, Physical therapy
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Unilateral Spastic Cerebral Palsy
Robotic Glove Training on Hand Function in Unilateral Cerebral Palsy
The purpose of the study is to investigate the effect of task-oriented robotic glove training on hand function in children with unilateral spastic cerebral palsy.
- Trial name
- NCT07482631
- Testing
- Conventional Physical Therapy Program, Robotic Glove Training
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Cerebral Palsy, Spastic
Effect of Robotic Assisted Therapy on Hand Functions, Grip Strength and Proprioception in Children With Hemiplegia
Statement of the problem: Does robotic assisted therapy have an effect on hand functions, grip strength and proprioception in children with hemiplegic cerebral palsy? Significance of the study: New technologies allow and promote…
- Trial name
- NCT07249866
- Testing
- Hand rehabilitation robotic gloves, occupational therapy
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Hereditary Spastic Paraplegia, Neurodegenerative Diseases
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders.
- Conditions
- Hereditary Spastic Paraplegia, Neurodegenerative Diseases, Pediatric Disorder, Spasticity, Muscle
- Trial name
- NCT05354622
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay, Spastic Paraplegia 7
Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias
Spastic ataxias are a group of diseases causing symptoms such as walking difficulties and balance impairments that lead to a high risk of falls. No pharmacological treatments exist to treat these diseases.
- Trial name
- NCT06261424
- Testing
- IMPACT - rehabIlitation prograM for sPAstiC aTaxias
- Where
- 5 sites in Canada
- Volunteers
- 84 people
- Sponsor
- Laval University
Cerebral Palsy, Gait Disorders, Neurologic
Precision Gait Retraining for Children With Cerebral Palsy
This project will develop the first sensor-based mobile Pelvic Assist Device (mPAD) that can deliver precise, adaptable, pelvic control to restore natural coordination of upper- and lower-limb movements during gait in children…
- Trial name
- NCT04717323
- Testing
- mPAD (or TPAD) Pelvic Assist Device, No Intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Spastic Cerebral Palsy
Halliwick and Aquatic Exercises in Spastic Cerebral Palsy
The aim of this research is to find and compare the effects of halliwick exercises and aquatic exercises on gross motor function, trunk stability and hand function in spastic cerebral palsy.
- Trial name
- NCT05322759
- Testing
- aquatic exercises, halliwick exercise programme
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University