Clinical trials: Speech and Language Disorder
Selective Mutism
The Efficacy of Integrated Behavioral Therapy for Selective Mutism
This study examines the efficacy of the Integrated Behavioral Therapy for Selective Mutism protocol (Bergman et al., 2013). Participants are 60 children, aged 4-8 years, diagnosed with Selective Mutism (SM).
- Trial name
- NCT04585048
- Testing
- Integrated Behavioral Therapy for Selective Mutism
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Dysarthria as Late Effect of Stroke
Efficacy of a Digital Therapeutic for People With Dysarthria After Stroke
This pilot trial will establish the feasibility of a new digitized speech rehabilitation developed for patients with post-stroke dysarthria.
- Trial name
- NCT05146765
- Testing
- Mobile application, Treatment as usual
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ewha Womans University Seoul Hospital
Developmental Delay, Child Development
Validity and Reliability of Indonesian Translated Ages and Stages Questionnaires - Third Edition (ASQ-3) as a Screening Tool for Developmental Delay in 1-12 Months Old Children
This study aimed to provide the validity and reliability of the Indonesian ASQ-3 questionnaires as a screening tool for developmentally delayed children aged less than one year old. This study was divided into 2 phases.
- Conditions
- Developmental Delay, Child Development, Child Development Disorder, Global Developmental Delay
- Trial name
- NCT05398900
- Where
- Indonesia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Developmental Language Disorder and Language Impairment, Deprivation
Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial.
The overall aim of this clinical trial is to evaluate an at scale version of 'Happy Talk' in a large scale effectiveness study (examining inputs, outputs and outcomes) based on a sample of children from socially disadvantaged…
- Trial name
- HappyTalk (NCT06460090)
- Testing
- Happy Talk
- Where
- 4 sites in Ireland
- Volunteers
- 840 people
- Sponsor
- University College Cork
Primary Progressive Aphasia
Preventing Language Decline in Dementia
This study will establish factors fundamental to the improvement in communication and quality of life for people with dementia known as primary progressive aphasia (PPA).
- Trial name
- NCT02541097
- Testing
- Language therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Baycrest
Dyslexia
Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years
Studies of dyslexia have shown altered oscillatory activity in the low gamma band (~25-35 Hz) in the left auditory cortex. Neural oscillations around 30 Hz constitute the basic sampling rate of speech, from which the ability to…
- Trial name
- RnDys (NCT05996497)
- Testing
- behavioral measures, Electrophysiological measures, Training 1
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Institut Pasteur
Stuttering
Genetic Factors Related to Stuttering
Stuttering is an abnormality in speech that affects the rhythm of speech. People who stutter know what they wish to say, but at the time are unable to say it because of involuntary repetition, unnecessary lengthening…
- Trial name
- NCT00001602
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Psychotic Disorders, Psychosis
Semantic and Syntactic Computerized Analysis of Free Speech
Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic…
- Conditions
- Psychotic Disorders, Psychosis, Schizophrenia and Related Disorders, Schizophrenia Prodromal
- Trial name
- ASESID (NCT03525054)
- Where
- 3 sites in France
- Volunteers
- 215 people
- Sponsor
- University Hospital, Brest
Selective Mutism
Randomised Controlled Treatment Study of Selective Mutism
Selective mutism (SM) describes inhibited and withdrawn children who are persistently mute in central situations despite ability to talk. SM may cause great suffering and create problems, both socially and related to learning.
- Trial name
- NCT01002196
- Testing
- Stimulus fading procedures, Guidance on defocused communication
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Regionsenter for barn og unges psykiske helse
Stuttering
Development and Pilot Testing of Virtually Simulated Intervention for Patients Having Stuttering
This study aims to develop and pilot test a culturally appropriate virtual reality (VR)-based speech restructuring intervention for individuals with stuttering in Pakistan.
- Trial name
- NCT07833969
- Testing
- Virtually Simulated Intervention
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Riphah International University
Selective Mutism
Web-Based CBT Protocol for Treatment of Selective Mutism
The main aim of this study is to examine the effectiveness of a web-based CBT protocol (entitled Meeky Mouse) in the treatment of children with Selective Mutism in Singapore.
- Trial name
- NCT02009839
- Testing
- Meeky Mouse program, Computer Games
- Where
- Singapore
- Volunteers
- 38 people
- Sponsor
- National Healthcare Group, Singapore
Primary Progressive Aphasia, Neurodegenerative Diseases
Home-Based Exercise in Primary Progressive Aphasia (HEPPA)
This pilot study aims to evaluate the feasibility of a novel home-based multicomponent exercise program in adults clinically diagnosed with Primary Progressive Aphasia
- Conditions
- Primary Progressive Aphasia, Neurodegenerative Diseases, Logopenic Progressive Aphasia, Semantic Dementia
- Trial name
- HEPPA (NCT06181500)
- Testing
- Home-based multicomponent exercise intervention program
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Montreal Heart Institute
Aphasia
Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia
Aphasia is a loss of language due to stroke or other brain injury. Word-finding in conversation is a universal and persistent difficulty in aphasia.
- Trial name
- NCT03550092
- Testing
- Abstract Semantic Association Network Training (AbSANT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Penn State University
Selective Mutism, Social Anxiety
Evaluating the Results of Physician and Parent Decisions to Treat Selective Mutism With Fluoxetine
The Department of Counseling, Educational Psychology, and Special Education and the Department of Psychiatry at Michigan State University have coordinated efforts to provide a diagnostic and treatment investigation for children…
- Trial name
- NCT05378711
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Michigan State University
Social Phobia
Treatment of Childhood Social Phobia
This 4-year study will compare the long-term effectiveness of behavioral treatment, fluoxetine (Prozac®), and placebo for treatment of social phobia in children and adolescents.
- Trial name
- NCT00043537
- Testing
- Social Effectiveness Therapy for Children (SET-C), Fluoxetine
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Developmental Stuttering, Evoked Potentials Auditory
Effect of Stuttering Remediation Exercises on Cortical Auditory Evoked Potentials
studying how the cortical auditory evoked potentials differ in children who stutter from who do not stutter and how these potentials change with therapy
- Trial name
- NCT05473572
- Testing
- Fluency shaping exercises
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alaa Mamdouh
Language Development Disorders, Speech and Language Disorder
Efficiency of Speech and Language Intervention on Achievement of Children With Developmental Language Disorder
Children with Developmental Language Disorder (DLD) have many linguistic difficulties in syntax, lexicon, morphology and phonology.
- Conditions
- Language Development Disorders, Speech and Language Disorder, Therapy
- Trial name
- DYSPHADEV (NCT04926311)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Stuttering, Down Syndrome
How Stuttering and Gestures Influence the Intelligibility of Individuals With Down Syndrome
This study wants to determine the relationship between spontaneous hand gestures, stuttering and intelligibility in individuals with Down syndrome. One third of these individuals has fluency problems, such as stuttering.
- Conditions
- Stuttering, Down Syndrome, Intelligibility, Speech, Gestures
- Trial name
- NCT03698539
- Testing
- hand gestures
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Spasticity
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected…
- Trial name
- Andreani1 (NCT02199015)
- Testing
- Lateral spinal cord surgical implant of electrodes
- Where
- 2 sites in Argentina, Germany
- Volunteers
- 40 people
- Sponsor
- Juan Carlos M. Andreani MD
Language and Speech Disorder, Psychiatric Nursing, Mental Health, Pet Therap
The Effect of Animal-Assisted Activity Programme Based on Human Caring Theory on Perceived Stress, Social Adaptation and Communication Skills of Children With Speech and Language Disorders
Animal-assisted practice is an intervention method explained with different mechanisms and theories that provides protection and development of health through human-animal interaction.
- Trial name
- NCT07512180
- Testing
- Nursing Care
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Şeyma Demiralay