Clinical trials: Spinal Decompression
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postoperative Pain, Postoperative Laminectomy Pain
Postoperative Analgesia in Laminectomy
Compare the analgesic effects of naproxen sodium codeine, paracetamol codeine and placebo on postoperative pain and tramadol (Contramal) consumption during the first 24 hour after a lumbar disk surgery.
- Trial name
- (PAL) (NCT02255955)
- Testing
- 550 mg naproxen sodium and 30mg codeine, 300 mg paracetamol and 30 mg codeine
- Volunteers
- 75 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Cervical Spondylotic Myelopathy
Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy
The primary purpose of this study is to compare anterior and posterior surgical approach in treatment of CSM in terms of surgical complications and neurological, functional, disease-specific and quality of life outcomes measures.
- Trial name
- CSM (NCT00285337)
- Testing
- Laminectomy and Laminoplasty
- Where
- 13 sites in United States, Canada
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- AOSpine North America Research Network
Indications and Effectiveness for Extended Posterior Circumferential Decompression
Safety and Effectiveness of Extended Circumferential Decompression for Thoracic Ossification of Posterior Longitudinal Ligament
The study was to evaluate the indications, efficiency and safety of the extended posterior circumferential decompression technique for the treatment of thoracic ossification of posterior longitudinal ligament (TOPLL) with dura…
- Trial name
- NCT04910737
- Testing
- extended posterior circumferential decompressive surgery
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Cord Injuries
Epidural Decompression Surgery Within 24 Hours After Acute Spinal Cord Injury Improves Spinal Nerve Function
To compare the effects of early (within 24 hours) and delayed (exceed 24 hours) epidural decompression surgery on the recovery of spinal nerve function in patients with acute spinal cord injury (complete and incomplete) at…
- Trial name
- NCT03103516
- Testing
- early epidural decompression group, delayed epidural decompression group
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking University People's Hospital
Spinal Cord Injuries
Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling
QUESTION. Does duroplasty improve outcome after spinal cord injury? WHAT DO WE STUDY? We will investigate whether performing a surgical procedure called duroplasty improves outcomes after spinal cord injury.
- Trial name
- DISCUS (NCT04936620)
- Testing
- Duroplasty, Spinal surgery
- Where
- 34 sites in Austria, Belgium and 10 more
- Volunteers
- 222 people
- Sponsor
- St George's, University of London
Tumor of Spinal Cord
Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection
Objective to construct the related early activity program for patients with lumbar intraspinal tumor after hemilaminectomy, and evaluate the postoperative limb function exercise according to the content of the program.
- Trial name
- NCT04968730
- Testing
- Postoperative rehabilitation nursing
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Arnold-Chiari Malformation, Type 1, Chiari Malformation Type I
Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia
The purpose of this study is to determine whether a posterior fossa decompression or a posterior fossa decompression with duraplasty results in better patient outcomes with fewer complications and improved quality of life in…
- Conditions
- Arnold-Chiari Malformation, Type 1, Chiari Malformation Type I, Type I Arnold-Chiari Malformation, Syringomyelia
- Trial name
- NCT02669836
- Testing
- Posterior fossa decompression, Dural Augmentation
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Washington University School of Medicine
Lumbar Spinal Stenosis, Surgery
Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis
Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment.
- Trial name
- NCT04254757
- Testing
- Two different treatment
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation
Efficacy of Navigable Percutaneous Plasma Disc Decompression Device (L'DISQ) in Patients With Severe Lumbar Disc Herniation
This study aims to assess the clinical outcome of percutaneous disc decompression using the L'DISQ in patients with severe lumbar disc herniation (LDH).
- Trial name
- L'DISQ (NCT05231759)
- Testing
- L'DISQ
- Volunteers
- 30 people
- Sponsor
- Korea University Anam Hospital
Failed Back Surgery Syndrome
Low Level Laser Therapy to Reduce Comorbidity in Spinal Surgery
Each year, more than one million individuals worldwide are submitted to laminectomies, with a failure rate higher than 40%. Postlaminectomy epidural adhesion is implicated as a main cause of ''failed back surgery syndrome'' and…
- Trial name
- LASPINE (NCT02529657)
- Testing
- Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Achondroplasia
A Clinical Trial to Evaluate Safety of Vosoritide in At-risk Infants With Achondroplasia
Study 111-209 is a Phase 2 randomized, open-label clinical trial of BMN 111 in infants and young children with a diagnosis of Achondroplasia at a heightened risk of requiring cervicomedullary decompression surgery
- Trial name
- NCT04554940
- Testing
- vosoritide
- Where
- 3 sites in Australia, United Kingdom
- Volunteers
- 20 people
- Sponsor
- BioMarin Pharmaceutical
Cervical Spinal Cord Injury
Laminectomy Alone Versus Laminectomy and Fusion for Traumatic Cervical Spinal Cord Injury Without Instability
The aim of study is to compare clinical and radiological outcomes of laminectomy alone to laminectomy and fusion in the treatment of traumatic cervical spinal cord injury without instability.
- Trial name
- NCT05360524
- Testing
- Laminectomy alone versus laminectomy and fusion
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Cervical Disc Prolapse
Functional Outcome After Combined Posterior Laminectomy and Anterior Cervical Discectomy and Fusion for Large Cervical Disc Prolapse
Cervical disc herniation (CDH) is the result of the displacement of the nucleus pulposus of the intervertebral disc, which may result in impingement of the traversing nerves as they exit the neural foramen or directly compressing…
- Trial name
- NCT06847503
- Volunteers
- 25 people
- Sponsor
- Assiut University
Tethered Cord Syndrome
Efficacy and Safety of Nerve Root Axial Decompression Surgery in The Treatment of Tethered Cord Syndrome
Background: Tethered cord syndrome (TCS) is a progressive clinical condition including a series of neurological dysfunctions and deformities attributable to abnormally increased tension on the spinal cord, which is lacking…
- Trial name
- NCT03262844
- Testing
- Conservative treatment, Capsule surgery
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Changzheng Hospital
Spinal Stenosis
The Coflex®COMMUNITY Study: An Observational Study of Coflex® Interlaminar Technology
The purpose of the coflexCOMMUNITY observational study is to collect information on patients with spinal stenosis undergoing back surgery with the coflex® implant, and to look at their outcomes and the cost-effectiveness of this…
- Trial name
- NCT02457468
- Testing
- coflex
- Where
- 28 sites in United States
- Volunteers
- 325 people
- Sponsor
- Predicted, Reported and Observed Outcomes Foundation
Chiari Malformation Type I, Tonsillectomy
PFDD Versus PFDRT in Chiari Decompression Surgery
The purpose of this study is to determine whether a posterior fossa decompression and duraplasty with or without tonsil manipulation results in better patient outcomes with fewer complications and improved quality of life in…
- Trial name
- NCT06079125
- Testing
- Posterior fossa decompression with duraplasty, PFDD with tonsillar resection/reduction
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Xuanwu Hospital, Beijing
Spinal Cord Injuries
Early Surgical Intervention Combined With Weight-supported Walking Training
To determine the efficacy of a novel combinatorial treatment involving early surgical intervention and long-term weight-bearing walking training in spinal cord injury (SCI) patients clinically diagnosed as complete or American…
- Trial name
- NCT04034108
- Testing
- Surgical intervention combined with weight-supported ambulation training
- Where
- 2 sites in China
- Volunteers
- 339 people
- Sponsor
- Kunming Tongren Hospital
Ossification of the Posterior Longitudinal Ligament
A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
The efficacy of laminoplasty and laminectomy with fusion for ossification of the posterior longitudinal ligament with high occupation rate in the cervical spine is not clear in the literature report so far.
- Trial name
- NCT05019001
- Testing
- Laminoplasty, Laminectomy With Fusion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital