Clinical trials: Spinal Hypotension
CerebroSpinal Fluid (CSF) Leak
The Freiburg Registry on SpontanEous IntercrAnial Hypotension (SIH) & Post-duraL Puncture Headache (PDPH)
Spinal CSF leaks are considered as rare disease. They cause a variety of symptoms, mainly culminating in a chronic headache syndrome. Crucially, yet often disregarded, the disease holds the potential for cure.
- Trial name
- SEAL (NCT06711731)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Freiburg
Transient Tachypnea of Newborn and Fetal Acidosis
Impact Of Maternal Spinal Anesthesia-Induced Hypotension At Scheduled Cesarean Delivery On Risk Development Of Transient Tachypnea Of Newborn And Fetal Acidosis
We will evaluate the association between transient tachypnea of newborns and fetal acidosis development to the degree and duration of maternal hypotension and anesthesia to delivery time during spinal anesthesia at scheduled…
- Trial name
- NCT06383624
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Benha University
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Hypotension, Regional Anesthesia Morbidity
Spinal Anesthesia Related Hypotension in SARS-CoV-2 (COVID-19) Pregnant Patients
Since the onset of COVID-19, recommendations suggest the use of neuraxial anesthesia, if possible, over general anesthesia for cesarian section to avoid the risks of aerosolization associated with tracheal intubation and…
- Conditions
- Hypotension, Regional Anesthesia Morbidity, SARS-CoV2 Infection
- Trial name
- NCT05085652
- Testing
- spinal anesthesia induced hypotension in SARS-CoV-2 patients.
- Where
- Turkey (Türkiye)
- Volunteers
- 251 people
- Sponsor
- Ankara City Hospital Bilkent
Hypotension
Effect of Position During Spinal Anesthesia on Hemodynamic Change in Cesarean Section
Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic.
- Trial name
- NCT02253381
- Testing
- Right, Left
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Prince of Songkla University
Hypotension, Fluid Overload
Inferior Venacava Ultrasound to Guide Fluid Management for Prevention of Hypotension After Spinal Anesthesia.
Hypotension is common during spinal anesthesia and contributes to underperfusion and ischemia. Severe episodes of intraoperative hypotension is an independent risk factor for myocardial infarction, stroke, heart failure, acute…
- Trial name
- NCT04736498
- Testing
- Inferior venacava Ultrasonography (IVC USG) guided fluid management
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Tribhuvan University, Nepal
Neuromuscular Diseases (NMD), ALS (Amyotrophic Lateral Sclerosis)
Invasive Home Ventilation in Denmark
The aim of this study is to describe national trends over the past 10 years in patients receiving invasive home mechanical ventilation (HMV) in Denmark.
- Conditions
- Neuromuscular Diseases (NMD), ALS (Amyotrophic Lateral Sclerosis), Spinal Cord Injuries (SCI), Duchenne Muscular Dystrophy (DMD)
- Trial name
- HOMEVENT DK (NCT07467187)
- Where
- Denmark
- Volunteers
- 450 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypotension, Cesarean Section
Comparison of Hypotension During Spinal Anaesthesia for C-section
Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.
- Conditions
- Hypotension, Cesarean Section, Aortocaval Compression
- Trial name
- NCT05427968
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Rawalpindi Medical College
Cesarean Section Complications, Anesthesia Complication
Prophylactic Phenylephrine Co-administration During Caesarean Section
This single centre prospective alternating intervention study will aim to compare prophylactic phenylephrine given in the first litre of Ringers lactate as co-load in healthy patients having an elective caesarean section under…
- Trial name
- NCT04005664
- Testing
- Phenylephrine
- Where
- South Africa
- Volunteers
- 300 people
- Sponsor
- University of KwaZulu
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Obstetric Anesthesia, Spinal Anesthesia
ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia
The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a cesarean section under spinal…
- Conditions
- Obstetric Anesthesia, Spinal Anesthesia, Hypotension, Fluid Therapy
- Trial name
- NCT01415284
- Testing
- Hydroxyethylstarch 130/0.4
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Cesarean Section
Ondansetron Prior Spinal Anaesthesia
Since Ondansetron is commonly used during cesarean deliveries to treat nausea and vomiting, this study will observe the correlation between ondansetron administration and effect on hemodynamics in order to confirm that the use of…
- Trial name
- Ondansetron (NCT06431568)
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Cord Injuries, Orthostatic Hypotension
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
This study seeks to evaluate whether the speed (cadence) of lower extremity robotic movement has an impact on orthostatic hypotension and upright tolerance when training with the ErigoPro robotic tilt-stepper.
- Trial name
- NCT04029974
- Testing
- ErigoPro
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Methodist Rehabilitation Center
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Spinal Anesthesia, Cesarean Section
Predicting Spinal Hypotension in Cesarean Section
This prospective observational study investigates the predictive value of anthropometric and hemodynamic indices for spinal anesthesia-induced hypotension (SAIH) during cesarean section.
- Conditions
- Spinal Anesthesia, Cesarean Section, Hypotension
- Trial name
- prediction (NCT07499947)
- Where
- Turkey (Türkiye)
- Volunteers
- 321 people
- Sponsor
- TC Erciyes University
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Cesarean Section
Two Syringe Spinal Anesthesia Technique for Cesarean Section: A Simple Way to Achieve More Satisfactory Block and Less Hypotension
Background: Poor spinal anaesthesia block is common and is difficult to manage; so a technique to minimize its incidence is advisable. Hypotension is the commonest problem with spinal anesthesia.
- Trial name
- NCT02577432
- Testing
- fentanyl, Hyperbaric bupivacaine
- Volunteers
- 124 people
- Sponsor
- Dr. Soliman Fakeeh Hospital
Maternal Hypotension Syndrome, Cesarean
Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section
Spinal anesthesia is still the gold standard anesthetic method for elective and urgent cesarean section, the post spinal hypotension remains the most frequent complication of this procedure and is still responsible of…
- Trial name
- NCT03719625
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Neuromuscular Scoliosis
An Open-label Trial of Clevidipine for Controlled Hypotension During Spinal Fusion
The current study would prospectively evaluate the dosing requirements, efficacy and safety of clevidipine for controlled hypotension during spinal surgery in the pediatric population.
- Trial name
- NCT01645111
- Testing
- Clevidipine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nationwide Children's Hospital