Clinical trials: Spinal Injuries
Spina Bifida, Cerebral Palsy
Grand Valley State University (GVSU) Skills on Wheels
Manual wheelchairs (MWCs) are widely used by children with physical disabilities, yet many of these children are unable to use their wheelchair independently. Instead, they depend on others to push them.
- Conditions
- Spina Bifida, Cerebral Palsy, Genetic Disease, Spinal Cord Injuries
- Trial name
- NCT05339932
- Testing
- Manual Wheelchair Skills Training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Cervical Radiculopathy, Cervical Myelomalacia
Cervical Spinal Cord Signal Abnormalities in Patients With Cervical Radicular Pain
This prospective observational study aims to determine the prevalence of cervical spinal cord signal abnormalities, including myelomalacia, among adult patients presenting to a tertiary pain clinic with cervical radicular pain.
- Trial name
- CSCS (NCT07823426)
- Testing
- Clinical and Cervical MRI Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries
Effectiveness of NEUROM and tDCS for Motor Recovery in Chronic Paraplegia
Traumatic Spinal Cord Injury (TSCI) is a catastrophic, unexpected, and devastating event that can occur along the spinal column (cervical, thoracic, and lumbar).
- Trial name
- NEUROM (NCT04790149)
- Testing
- Conventional Rehabilitation, NEUROM + tDCS, NEUROM
- Where
- Lebanon
- Volunteers
- 56 people
- Sponsor
- Lebanese University
Spinal Cord Injury
The Canadian Multicentre CSF Monitoring and Biomarker Study
The purpose of this study is to: 1. Measure the pressure in the spinal fluid surrounding the spinal cord to find out how well the spinal cord is being supplied with blood. 2.
- Trial name
- CAMPER (NCT01279811)
- Testing
- Crossover of vasopressors
- Where
- 6 sites in United States, Canada
- Volunteers
- 86 people
- Sponsor
- University of British Columbia
Stroke, Spinal Cord Injury
Computer Game-based Exercise Program Targeting Manual Dexterity for People With Spinal Cord Injury or Stroke.
Recovery programs of the upper extremity can be extensive, for many adults with neurological disorders/injuries, including maintenance exercises that need to be done continually to maintain function and to prevent secondary…
- Trial name
- NCT05071885
- Testing
- games based exercise
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Manitoba
Spinal Cord Injury, Acute, Professional-Patient Relations
Effectiveness of Psycho-emotional Support in Acute Spinal Cord Injury. ESPELMA Project
The purposes of the ESPELMA project are twofold: 1) To increase acute spinal cord injury patients' satisfaction with treatment while hospitalization and 2) To increase mastery among rehabilitation professionals with regard to the…
- Conditions
- Spinal Cord Injury, Acute, Professional-Patient Relations, Sensitivity Training Groups, Patient Non-Compliance
- Trial name
- ESPELMA (NCT01889940)
- Testing
- Training for professionals (Spinal Cord Injury Unit staff).
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Spinal Cord Injury
Eyegaze Systems for Spinal Cord Injury: A Feasibility Study
As technologies are advancing quickly in the healthcare setting, new solutions have become available helping disable people to enhance their ability to communicate.
- Trial name
- NCT01943656
- Testing
- Tobii™ Eyegaze System
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Buckinghamshire Healthcare NHS Trust
Spinal Cord Injuries
Neuro-navigated TMS for Chronic SCI Patients
Can neuro-navigated Transcranial Magnetic Stimulation be used as an additional outcome measure to EM-SCI assessments in a Spinal cord injury trial? Compare EM-SCI assessment with nTMS in ten chronic thoracic SCI patients Compare…
- Trial name
- NCT06075056
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College Hospital NHS Trust
Spinal Cord Injuries (SCI)
Spatiotemporal tSCS in Spinal Cord Injury
Spinal cord injury leads to long-lasting impairment, and currently, there is no cure for paralysis. Although transcutaneous spinal cord stimulation has shown promising results in recovering lost movements, its poor selectivity in…
- Trial name
- NCT07397559
- Testing
- No Stimulation, Conventional tSCS, Spatiotemporal tSCS
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injury
Investigating Kinematic and Electromyographic Changes After SCI and Their Relation to Clinical and Functional Outcome
The study aims at discerning specific gait patterns and elucidating locomotor control of spinal cord injured patients in order to find sensitive kinematic and electromyographic outcome measures that are able to reveal information…
- Trial name
- NCT02150629
- Where
- Switzerland
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Spinal Cord Injuries
Prospective Survey of Body Mass Index in People With Spinal Cord Injury.
This study is a prospective national survey of body mass index, and includes all patients with a new spinal cord injury hospitalized at Clinic for Spinal Cord Injuries, Rigshospitalet and Spinal Cord Injury Center of Western…
- Trial name
- NCT03369080
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Cord Injury, Incomplete Spinal Cord Injury
Evaluation of Robotic Exoskeletons Therapy for Gait Rehabilitation in Patients With Incomplete Spinal Cord Injury.
The objective of the study is to assess the efficacy of the Exo-H2 robotic exoskeleton for walking rehabilitation of people with incomplete spinal cord injury.
- Trial name
- NCT03477123
- Testing
- Walking therapy with Exo-H2 exoskeleton
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo
Spinal Cord Injuries (SCI), Spinal Cord Injury
Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation
This clinical trial primarily aims to evaluate the safety and feasibility of a combined therapeutic approach for chronic spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Traumatic Spinal Cord Injuries, Spinal Cord Disease
- Trial name
- GNR-SCI-01 (NCT06981338)
- Testing
- Allogeneic Wharton's jelly mesenchymal stem cells (WJ-MSCs)
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut Guttmann
Cervical Spinal Cord Injury
Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
The purpose of this study is to determine the efficacy and safety of VX-210 in subjects with Acute Traumatic Cervical Spinal Cord Injury.
- Trial name
- NCT02669849
- Testing
- VX-210
- Where
- 39 sites in United States, Canada
- Volunteers
- 70 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Athletic Injuries
Effects of Lumbosacral Chiropractic on the Olympic Style Weightlifting Athletes
It is known that low back injuries experienced by weightlifting athletes cause a decrease in performance. The effects of spinal manipulative therapy, which has been found to positively affect performance in various sports, are…
- Trial name
- NCT04668729
- Testing
- Chiropractic Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis
European Home Mechanical Ventilation Registry
The European Home Mechanical Ventilation Registry (EHMVR) will enable a thorough evaluation of HMV by documenting the characteristics of HMV patients and their treatment.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis, Spinal Cord Injury, Muscular Dystrophies
- Trial name
- EHMVR (NCT02315339)
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- ResMed
Spasticity as Sequela of Stroke, Spastic Cerebral Palsy
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurgery dorsal rhizotomy." It uses very accurate beams of radiation to…
- Conditions
- Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
- Trial name
- SPASM (NCT06070233)
- Testing
- stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Ohio State University
Cerebral Palsy, Mobility Limitation
Robotic Walking for Children Who Cannot Walk
A common problem among children with nervous system disorders is difficulty walking on their own. This has impacts beyond mobility including short and long-term health conditions associated with physical inactivity and different…
- Conditions
- Cerebral Palsy, Mobility Limitation, Brain Injuries, Spinal Cord Injuries
- Trial name
- RoWaCaWa (NCT05473676)
- Testing
- Robotic Training Period
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Calgary
Scoliosis
Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury
The purpose of this study is to determine whether full-time high dose prophylactic bracing (23 hours or more per day) is more effective than low dose bracing (12 hours or less per day) in preventing or delaying spinal curve…
- Trial name
- NCT00256672
- Testing
- Thoraco-Lumbar-Sacral-Orthoses (TLSO) / Flex-Foam
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Shriners Hospitals for Children
Hip Fracture
Analgesia for Positioning Hip Fracture Patients for Spinal Anesthesia
The purpose of this study is to compare two analgesic methods performed preoperatively to assist positioning patients for performance of spinal anesthesia, namely fascia iliaca blockade and intravenous fentanyl.
- Trial name
- NCT02037633
- Testing
- Fentanyl, Fascia iliaca compartment block, ropivacaine
- Where
- Greece
- Volunteers
- 41 people
- Sponsor
- Asklepieion Voulas General Hospital